{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:34:56Z","timestamp":1762353296567,"version":"build-2065373602"},"reference-count":27,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    Hydatid disease, caused by the parasitic tapeworm\n                    <jats:italic>Echinococcus<\/jats:italic>\n                    , remains a significant public health issue, especially in regions where livestock farming is prevalent. This retrospective study, conducted in the microbiology department of a tertiary care center in North India, is designed to assess the epidemiological trends of hydatid disease over the past 5 years in a tertiary care hospital, focusing on incidence, demographic patterns, clinical characteristics, and diagnostic improvements. During the study period, 843 patients were tested for\n                    <jats:italic>Echinococcus<\/jats:italic>\n                    IgG antibodies. Among them, 400 cases were confirmed positive and 443 were negative for\n                    <jats:italic>Echinococcus<\/jats:italic>\n                    IgG antibodies. Data were retrieved from the hospital\u2019s information system, focusing on ELISA results for\n                    <jats:italic>Echinococcus<\/jats:italic>\n                    IgG antibodies. Demographic variables, such as age, sex, and clinical and histopathological parameters, were recorded for the patients. Of 400 positive cases, 54% were male, and 46% were female, with a mean age of 45 years. The highest incidence was found in the 31- to 40-year-old age group. Biochemical analysis revealed significant differences between the positive and negative groups across all parameters (\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.01). Of 60 patients, the liver was the most predominant organ involved (in 53.3% of cases), followed by the lungs (in 26.7% of cases), and then the spleen and gallbladder (in 6.7% of cases each). Less common sites included the retroperitoneal organs, heart, and renal organs (1.7% of cases each). This study underscores the importance of early detection and heightened clinical suspicion, as well as the value of serological testing in diagnosing and managing this parasitic infection.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.24-0853","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T15:46:15Z","timestamp":1758642375000},"page":"1052-1056","source":"Crossref","is-referenced-by-count":0,"title":["Hydatid Disease Over the Last 5 Years: Experiences from a Tertiary Care Center in India"],"prefix":"10.4269","volume":"113","author":[{"given":"Urvashi","family":"Goyal","sequence":"first","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nidhi","family":"Tejan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashima","family":"Jamwal","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ram","family":"Naval","sequence":"additional","affiliation":[{"name":"Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerlin","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irfan","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akash","family":"Pal","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Health Informatics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ujjala","family":"Ghoshal","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences, Kalyani, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chinmoy","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Awadhesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Cureus","first-page":"e63174","article-title":"Primary hydatid cysts in the extremities: A systematic review of the literature","volume":"16","author":"Paspala","year":"2024"},{"key":"b2","series-title":"Sci Rep","first-page":"26094","article-title":"The prevalence of hydatid cyst in raw meat products: A global systematic review, meta-analysis, and meta-regression","volume":"14","author":"Fakhri","year":"2024"},{"key":"b3","series-title":"Vet Med Int","first-page":"8859116","article-title":"Review on epidemiology and public health significance of hydatidosis","volume":"2020","author":"Gessese","year":"2020"},{"key":"b4","series-title":"Heliyon","first-page":"e01897","article-title":"A retrospective study of hydatid cysts in patients undergoing liver and lung surgery in Tehran, Iran","volume":"5","author":"Moradi","year":"2019"},{"key":"b5","series-title":"J Lab 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hydatidosis","volume":"44","author":"Uriarte","year":"1991"},{"key":"b20","series-title":"N Am J Med Sci","first-page":"10","article-title":"Hydatid cyst of spleen: A diagnostic challenge","volume":"5","author":"Rasheed","year":"2013"},{"key":"b21","series-title":"Lancet","first-page":"1295","article-title":"Echinococcosis","volume":"362","author":"McManus","year":"2003"},{"key":"b22","series-title":"Iran J Public Health","first-page":"1277","article-title":"Human cystic echinococcosis in Zanjan area, Northwest Iran: A retrospective hospital-based survey between 2007 and 2013","volume":"44","author":"Kohansal","year":"2015"},{"key":"b23","series-title":"Updates Surg","first-page":"279","article-title":"Unusual locations of hydatid disease: A 33-year experience analysis on 233 patients","volume":"67","author":"Lianos","year":"2015"},{"key":"b24","series-title":"Surg Infect (Larchmt)","first-page":"349","article-title":"Unusual locations of hydatid disease: Diagnostic and surgical management of a case series","volume":"11","author":"Ca\u011flayan","year":"2010"},{"key":"b25","series-title":"BMC Surg","first-page":"9","article-title":"Diagnostic problems with parasitic and non-parasitic splenic cysts","volume":"9","author":"Adas","year":"2009"},{"key":"b26","series-title":"J Postgrad Med","first-page":"112","article-title":"Primary retroperitoneal hydatid cyst (a report of 3 cases and review of the literature)","volume":"28","author":"Sekar","year":"1982"},{"key":"b27","series-title":"Int J Curr Microbiol Appl Sci","first-page":"195","article-title":"Role of serology in diagnosis of human hydatidosis: Experience from a tertiary care hospital","volume":"5","author":"Madiyal","year":"2016"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/5\/article-p1052.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/5\/article-p1052.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/5\/article-p1052.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:25:40Z","timestamp":1762352740000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/5\/article-p1052.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,5]]},"references-count":27,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.24-0853","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2025,11,5]]}}}