{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T23:07:14Z","timestamp":1782169634259,"version":"3.54.5"},"reference-count":15,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>We report the case of two girls from a rural community in the Peruvian Amazon who were exposed to the rabies virus, with fatal outcomes in both cases. The reemergence of rabies in this endemic area after more than 11 years of successful control through massive immunization policies is highlighted in this report. In these cases, exposure occurred through contact with a domestic cat, although bat bites remain the most common source of rabies transmission in the region. Adopting a One Health approach and reinforcing periodic mass immunization campaigns are essential to prevent further outbreaks in endemic rabies zones.<\/jats:p>","DOI":"10.4269\/ajtmh.25-0032","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T11:34:41Z","timestamp":1750764881000},"page":"584-587","source":"Crossref","is-referenced-by-count":1,"title":["Reemergence of Human Rabies in an Endemic Peruvian Amazon Region"],"prefix":"10.4269","volume":"113","author":[{"given":"C\u00e9sar","family":"S\u00e1nchez-\u00c1lvarez","sequence":"first","affiliation":[{"name":"Hospital Nacional Dos de Mayo, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Chiappe-Gonzalez","sequence":"additional","affiliation":[{"name":"Instituto de Investigaciones en Ciencias Biom\u00e9dicas, Universidad Ricardo Palma, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristhian","family":"Resurrecci\u00f3n Delgado","sequence":"additional","affiliation":[{"name":"Instituto de Investigaciones en Ciencias Biom\u00e9dicas, Universidad Ricardo Palma, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Paz-Majluf","sequence":"additional","affiliation":[{"name":"Hospital Nacional Dos de Mayo, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rotciv","family":"Arteaga-Vega","sequence":"additional","affiliation":[{"name":"Hospital Nacional Dos de Mayo, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"L\u00f3pez-Fuentes","sequence":"additional","affiliation":[{"name":"Hospital Nacional Dos de Mayo, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Jos\u00e9","family":"Montenegro-Idrogo","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Universidad Cient\u00edfica del Sur, Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Anim Dis","first-page":"15","article-title":"Rabies in a postpandemic world: Resilient reservoirs, redoubtable riposte, recurrent roadblocks, and resolute recidivism","volume":"3","author":"Rupprecht","year":"2023"},{"key":"b2","series-title":"Expert Rev Vaccines","first-page":"629","article-title":"Current status of human rabies prevention: Remaining barriers to global biologics accessibility and disease elimination","volume":"18","author":"Rupprecht","year":"2019"},{"key":"b3","series-title":"Bol Inst Nac Salud","first-page":"45","article-title":"Situaci\u00f3n de la rabia en el Per\u00fa, INS, 2015\u20132017","volume":"24","year":"2018"},{"key":"b4","article-title":"Experiencia de Control de Rabia Silvestre en Amazonas","year":"2021"},{"key":"b5","series-title":"Bull World Health Organ","first-page":"210","article-title":"Pre-exposure rabies prophylaxis: A systematic 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Gelephu, Bhutan, 2023: A case report","volume":"12","author":"Dorji","year":"2023"},{"key":"b11","series-title":"J Venom Anim Toxins Incl Trop Dis","first-page":"6","article-title":"Rabies review: Immunopathology, clinical aspects and treatment","volume":"13","author":"Consales","year":"2007"},{"key":"b12","series-title":"PLoS Negl Trop Dis","first-page":"e0006271","article-title":"Rabies in the Americas: 1998\u20132014","volume":"12","author":"Freire de Carvalho","year":"2018"},{"key":"b13","series-title":"Rev Soc Bras Med Trop","first-page":"e003002024","article-title":"Human rabies during the COVID-19 pandemic: Insights into rabies worldwide and Brazil","volume":"57","author":"Farias","year":"2024"},{"key":"b14","series-title":"PLoS Negl Trop Dis","first-page":"e0009414","article-title":"The impact of the COVID-19 pandemic on rabies reemergence in Latin America: The case of Arequipa, Peru","volume":"15","author":"Raynor","year":"2021"},{"key":"b15","series-title":"Acta 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