{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T15:09:04Z","timestamp":1771859344393,"version":"3.50.1"},"reference-count":17,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>High rates of human T cell lymphotropic virus type 1 (HTLV-1) and human T cell lymphotropic virus type 2 (HTLV-2) infections have been reported among Andean and Amazonian Peruvian indigenous populations in Peru. The Shipibo-Konibo people are the third-largest Amazonian indigenous group living in Peru. By using data from two observational studies conducted in the Shipibo-Konibo community, we estimated that the risk of all-cause death at 12 years was 3.11 times higher (95% CI: 1.58\u20136.10) for people with HTLV-1 infection compared with those with HTLV-2 infection or without HTLV-1 and HTLV-2 infections.<\/jats:p>","DOI":"10.4269\/ajtmh.25-0082","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T11:34:42Z","timestamp":1750764882000},"page":"573-575","source":"Crossref","is-referenced-by-count":2,"title":["Human T Cell Lymphotropic Virus Type 1 and Human T Cell Lymphotropic Virus Type 2 Mortality in the Shipibo-Konibo People"],"prefix":"10.4269","volume":"113","author":[{"given":"Isaac E.","family":"Alva","sequence":"first","affiliation":[{"name":"Alexander von Humboldt Tropical Medicine Institute, Universidad Peruana Cayetano Heredia, Lima, Peru;"},{"name":"Intercultural Citizenship and Indigenous Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magaly M.","family":"Blas","sequence":"additional","affiliation":[{"name":"Intercultural Citizenship and Indigenous Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicanor","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Neurology, Daniel Alcides Carrion National Hospital, Callao, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Sal y Rosas","sequence":"additional","affiliation":[{"name":"Pontificia Universidad Cat\u00f3lica del Per\u00fa, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"de la Cruz","sequence":"additional","affiliation":[{"name":"Pontificia Universidad Cat\u00f3lica del Per\u00fa, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph R.","family":"Zunt","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Washington, Seattle, Washington;"},{"name":"Department of Global Health, University of Washington, Seattle, Washington;"},{"name":"Department of Medicine, University of Washington, Seattle, Washington;"},{"name":"Department of Epidemiology, University of Washington, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Gotuzzo","sequence":"additional","affiliation":[{"name":"Alexander von Humboldt Tropical Medicine Institute, Universidad Peruana Cayetano Heredia, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Rev Panam Salud Publica","first-page":"44","article-title":"HTLV in the Americas: Challenges and perspectives","volume":"19","author":"Carneiro-Proietti","year":"2006"},{"key":"b2","series-title":"Clin Microbiol Rev","first-page":"577","article-title":"Epidemiology, treatment, and prevention of human T-cell leukemia virus type 1-associated diseases","volume":"23","author":"Gon\u00e7alves","year":"2010"},{"key":"b3","series-title":"Lancet Infect Dis","first-page":"133","article-title":"Association between HTLV-1 infection and adverse health outcomes: A systematic review and meta-analysis of epidemiological studies","volume":"20","author":"Schierhout","year":"2020"},{"key":"b4","series-title":"Front Microbiol","first-page":"1217134","article-title":"Long-term prevalence follow-up (1967-2022) of HTLV-2 among vulnerable indigenous populations in the Amazon region of Brazil","volume":"14","author":"Ishak","year":"2023"},{"key":"b5","series-title":"PLoS Negl Trop Dis","first-page":"e2272","article-title":"Familial transmission of human T-cell lymphotrophic virus: Silent dissemination of 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Sci","first-page":"587","article-title":"Human T cell lymphotropic viruses (HTLV-I\/II) in South America: Should it be a public health concern?","volume":"9","author":"Carneiro-Proietti","year":"2002"},{"key":"b11","series-title":"Rev Panam Salud Publica","first-page":"7","article-title":"HTLV in the Americas","volume":"19","author":"Proietti","year":"2006"},{"key":"b12","series-title":"Trop Med Int Health","first-page":"934","article-title":"Human T-cell lymphotropic virus type 1 and associated diseases in Latin America","volume":"24","author":"Eusebio-Ponce","year":"2019"},{"key":"b13","series-title":"Rev Inst Med Trop Sao Paulo","first-page":"1","article-title":"Origin and prevalence of human T-lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2) among indigenous populations in the Americas","volume":"57","author":"Paiva","year":"2015"},{"key":"b14","series-title":"Am J Trop Med Hyg","first-page":"954","article-title":"HTLV-1 and -2 infections among 10 indigenous groups in the 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