{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T14:43:40Z","timestamp":1773672220054,"version":"3.50.1"},"reference-count":19,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Vertebral hydatidosis is a rare and severe form of echinococcosis with limited treatment options when surgery is not feasible. Radiotherapy has traditionally been considered ineffective, but emerging evidence suggests a potential role in disease control. We report the case of a 71-year-old man with chronic vertebral hydatidosis affecting fifth lumbar vertebra and the sacrum, causing nerve compression and soft tissue extension. Because of the inoperability of the lesion, the patient underwent radiology-guided drainage, followed by radiotherapy (54 gray in 27 fractions), resulting in significant clinical and radiological improvement, with no recurrence after 1 year. This case highlights radiotherapy as a promising adjunctive treatment in inoperable hydatidosis. The combination of radiotherapy with minimally invasive techniques may offer an effective therapeutic alternative. Further research is needed to establish its role in the management of complex cases.<\/jats:p>","DOI":"10.4269\/ajtmh.25-0181","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T14:31:31Z","timestamp":1753799491000},"page":"836-838","source":"Crossref","is-referenced-by-count":1,"title":["Non-Surgical Exceptional Management of Inoperable Hydatidosis with Radiotherapy: Case Report and Review of Literature"],"prefix":"10.4269","volume":"113","author":[{"given":"Maria F.","family":"Ramirez-Hidalgo","sequence":"first","affiliation":[{"name":"Tropical Medicine Section, Department of Internal Medicine, Arnau de Vilanova University Hospital, Lleida, Spain;"},{"name":"Nosocomial Infections Unit, Arnau de Vilanova University Hospital, Lleida, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moises","family":"Mira-Flores","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Arnau de Vilanova University Hospital, Lleida, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Lourdes","family":"Diaz","sequence":"additional","affiliation":[{"name":"Department of Radiology, Interventional Radiology Section, Arnau de Vilanova University Hospital, Lleida, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Tueros-Farfan","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Arnau de Vilanova University Hospital, Lleida, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pau","family":"Sol\u00e9 Florensa","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Arnau de Vilanova University Hospital, Lleida, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saray","family":"Mormeneo-Bayo","sequence":"additional","affiliation":[{"name":"Microbiology Section, Arnau de Vilanova University Hospital, Lleida, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Jover-S\u00e1enz","sequence":"additional","affiliation":[{"name":"Nosocomial Infections Unit, Arnau de Vilanova University Hospital, Lleida, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","article-title":"WHO\/OIE Manual on Echinococcosis in Humans and Animals: A Public Health Problem of Global Concern.","author":"Eckert","year":"2001"},{"key":"b2","series-title":"J Antimicrob Chemother","first-page":"821","article-title":"Treatment challenges associated with bone echinococcosis","volume":"69","author":"Steinmetz","year":"2014"},{"key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e2450","article-title":"Spinal cystic echinococcosis\u2013A systematic analysis and review of the literature","volume":"7","author":"Neumayr","year":"2013"},{"key":"b4","series-title":"Acta Trop","first-page":"1","article-title":"Expert consensus for the 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