{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T16:17:17Z","timestamp":1767802637827,"version":"3.49.0"},"reference-count":30,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,7]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Angiostrongylus cantonensis<\/jats:italic>\n                    meningitis is a parasitic disease of the central nervous system. Its diagnosis is challenging because it shows nonspecific clinical signs. In Mayotte, France, cases are reported annually, mainly in children. The key indicator is the presence of eosinophilic meningitis. We report the case of an 11-month-old infant seen in Mayotte with altered consciousness and fever. Lumbar puncture revealed an elevated white blood cell count in the cerebrospinal fluid (CSF) with a 100% lymphocytic formula. A brain computed tomography suggested tuberculosis but did not exclude parasitic infection. Blood tests showed significant eosinophilia. Empirical treatment of tuberculous meningitis was started. A second lumbar puncture showed 13% eosinophils, and the polymerase chain reaction for\n                    <jats:italic>A. cantonensis<\/jats:italic>\n                    was positive. This atypical case of lymphocytic meningitis could have caused a diagnostic error. In cases with strong clinical suspicion and absence of initial eosinophilic meningitis, it is essential to repeat CSF analysis and consider antiparasitic therapy.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.25-0213","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T17:04:04Z","timestamp":1762448644000},"page":"142-144","source":"Crossref","is-referenced-by-count":0,"title":["Angiostrongyliasis in an Infant Presenting as Lymphocytic Meningitis"],"prefix":"10.4269","volume":"114","author":[{"given":"Valentina Elisabeth Helene","family":"Bielli","sequence":"first","affiliation":[{"name":"UCLouvain University, Brussels, Belgium;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soraya","family":"Daoudi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, CHM Mamoudzou, Mayotte, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis","family":"Collet","sequence":"additional","affiliation":[{"name":"CHM Mamoudzou, Mayotte, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Delmas","sequence":"additional","affiliation":[{"name":"Pediatric and Prenatal Imaging Department, CHU Bordeaux, Bordeaux, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdourahim","family":"Chamouine","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, CHM Mamoudzou, Mayotte, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Am J Trop Med Hyg","first-page":"608","article-title":"Review of cases of angiostrongyliasis in Hawaii, 2007\u20132017","volume":"101","author":"Johnston","year":"2019"},{"key":"b2","series-title":"Rev Francoph Lab","first-page":"45","article-title":"L\u2019angiostrongylose humaine: une maladie tropicale n\u00e9glig\u00e9e","volume":"2016","author":"Epelboin","year":"2016"},{"key":"b3","series-title":"Am J Trop Med Hyg","first-page":"723","article-title":"Case report: Angiostrongylus cantonensis meningoencephalitis in a 9-month-old baby in Vietnam","volume":"103","author":"Pham Thu","year":"2020"},{"key":"b4","series-title":"PLoS Negl Trop Dis","first-page":"e0004635","article-title":"Angiostrongylus cantonensis infection on Mayotte Island, Indian Ocean, 2007\u20132012","volume":"10","author":"Epelboin","year":"2016"},{"key":"b5","series-title":"Pediatr Infect Dis J","first-page":"194","article-title":"Eosinophilic meningitis in a previously healthy 13-year-old child","volume":"32","author":"Thyssen","year":"2013"},{"key":"b6","series-title":"Clin Microbiol Rev","first-page":"322","article-title":"Update on eosinophilic meningoencephalitis and its clinical relevance","volume":"22","author":"Graeff-Teixeira","year":"2009"},{"key":"b7","series-title":"Parasitology","first-page":"227","article-title":"Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: Updated recommendations","volume":"148","author":"Ansdell","year":"2021"},{"key":"b8","article-title":"Preliminary Guidelines for the Diagnosis and Treatment of Neuroangiostrongyliasis (Rat Lungworm Disease) in Hawaii.","year":"2018"},{"key":"b9","series-title":"Pathogens","first-page":"624","article-title":"Neuroangiostrongyliasis: Updated provisional guidelines for diagnosis and case definitions","volume":"12","author":"Graeff-Teixeira","year":"2023"},{"key":"b10","series-title":"Am J Trop Med Hyg","first-page":"176","article-title":"Real-time polymerase chain reaction detection of Angiostrongylus cantonensis DNA in cerebrospinal fluid from patients with eosinophilic meningitis","volume":"94","author":"Qvarnstrom","year":"2016"},{"key":"b11","series-title":"Clin 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