{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T14:34:15Z","timestamp":1793716455999,"version":"4.6.1"},"reference-count":10,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    Intestinal schistosomiasis is an uncommon disease that can present with a range of clinical symptoms and colonoscopic findings, depending on the affected organ, disease extent, and duration. Because these manifestations are not disease-specific, diagnosis can be difficult without clinical suspicion. In addition to fecal examinations to detect parasite eggs, computed tomography (CT) plays a crucial role in diagnosing intestinal schistosomiasis because it can reveal hallmark calcification patterns that are strongly suggestive of\n                    <jats:italic>Schistosoma<\/jats:italic>\n                    infection. A case of a 50-year-old Filipino female patient who presented with persistent abdominal pain is reported in the current study. She had experienced chronic abdominal pain for 10 years, which had acutely worsened over the past several days before presentation, accompanied by diarrhea. A previous colonoscopy performed at a local hospital revealed a 2 cm ulcer at the ileocecal valve. She was subsequently referred to the study institution for further evaluation of possible inflammatory bowel disease and other differential diagnoses. A CT scan performed before the colonoscopy revealed map-like hepatic calcifications and curvilinear calcifications in the bowel wall, suggestive of schistosomiasis. A subsequent colonoscopy with rectal biopsy and molecular analysis of paraffin-embedded tissue confirmed the presence of\n                    <jats:italic>Schistosoma japonicum<\/jats:italic>\n                    infection. The patient responded well to praziquantel.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.25-0229","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T17:44:33Z","timestamp":1755193473000},"page":"1022-1024","source":"Crossref","is-referenced-by-count":1,"title":["A Case of Intestinal Schistosomiasis with Concurrent Hepatic and Gastrointestinal Involvement Diagnosed by Computed Tomography"],"prefix":"10.4269","volume":"113","author":[{"given":"Seong-Jung","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, South Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Jeong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, South Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Chul","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Pathology, College of Medicine, Chosun University, Gwangju, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da Hae","family":"Kwak","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, South Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Min","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, South Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"World J Gastroenterol","first-page":"723","article-title":"Endoscopic findings and clinicopathologic characteristics of colonic schistosomiasis: A report of 46 cases","volume":"16","author":"Cao","year":"2010"},{"key":"b2","series-title":"Radiol Infect Dis","first-page":"150","article-title":"Human schistosomiasis: A diagnostic imaging focused review of a neglected disease","volume":"2","author":"Sah","year":"2015"},{"key":"b3","series-title":"J Clin Pathol","first-page":"487","article-title":"Improving the specific diagnosis of trematode, cestode and nematode infections by a multiplex single-tube real-time PCR assay","volume":"72","author":"Wong","year":"2019"},{"key":"b4","series-title":"Gut","first-page":"439","article-title":"Schistosomal colonic disease","volume":"31","author":"Mohamed","year":"1990"},{"key":"b5","series-title":"N Engl J Med","first-page":"1212","article-title":"Schistosomiasis","volume":"346","author":"Ross","year":"2002"},{"key":"b6","series-title":"Lancet","first-page":"86","article-title":"Schistosomiasis in expatriates returning to Britain from the tropics: A controlled study","volume":"1","author":"Harries","year":"1986"},{"key":"b7","series-title":"BMC Gastroenterol","first-page":"12","article-title":"The clinical features of chronic intestinal schistosomiasis-related intestinal lesions","volume":"21","author":"Qin","year":"2021"},{"key":"b8","series-title":"BMJ","first-page":"d2651","article-title":"Diagnosis and management of schistosomiasis","volume":"342","author":"Gray","year":"2011"},{"key":"b9","series-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi","first-page":"200","article-title":"[CT manifestation of abdomen and its pathology of patients with chronic schistosomiasis]","volume":"24","author":"Shen","year":"2012"},{"key":"b10","series-title":"Front Public Health","first-page":"1558564","article-title":"Prevention and control of schistosomiasis in the Philippines from a health education perspective","volume":"13","author":"Yao","year":"2025"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/5\/article-p1022.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/5\/article-p1022.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/5\/article-p1022.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:22:58Z","timestamp":1762352578000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/5\/article-p1022.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,5]]},"references-count":10,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.25-0229","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,5]]}}}