{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:09:10Z","timestamp":1780499350458,"version":"3.54.1"},"reference-count":22,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    We report a case of lymphocutaneous nocardiosis in a 73-year-old male lung transplant recipient after traumatic soil exposure abroad. The patient traveled from Portugal to Brazil to undergo lung transplantation and, 3 months later, while receiving immunosuppressive therapy (with prednisolone, mycophenolate mofetil, and tacrolimus), sustained a nasal laceration after a fall onto soil-contaminated ground in Brazil. A persistent ulcerated facial lesion subsequently developed and was initially misdiagnosed as sporotrichosis, leading to treatment with itraconazole. Despite partial improvement, the patient later developed progressive bilateral parotid and submandibular lymphadenopathy. After returning to Portugal, imaging revealed necrotic cervical lymph nodes. Fine-needle aspiration specimens tested positive for\n                    <jats:italic>Nocardia<\/jats:italic>\n                    spp. by polymerase chain reaction, and\n                    <jats:italic>Nocardia asiatica<\/jats:italic>\n                    was isolated and identified by MALDI-TOF and 16S rRNA sequencing. Pulmonary and central nervous system involvement were excluded. Antifungal therapy was discontinued and trimethoprim-sulfamethoxazole initiated, resulting in progressive clinical improvement. This case underscores the importance of considering nocardiosis in transplant recipients with cutaneous lesions and lymphadenopathy after soil exposure, particularly in settings where other endemic infections may bias initial diagnostic assumptions, and emphasizes the importance of microbiological confirmation.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.25-0374","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T15:22:38Z","timestamp":1776352958000},"page":"1089-1091","source":"Crossref","is-referenced-by-count":0,"title":["Nocardia asiatica Lymphadenitis in a Lung Transplant Recipient Following Travel"],"prefix":"10.4269","volume":"114","author":[{"given":"Rafael","family":"Rocha","sequence":"first","affiliation":[{"name":"Infectious Diseases Department, S\u00e3o Jo\u00e3o Hospital, S\u00e3o Jo\u00e3o Local Health Unit, Porto, Portugal;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Ara\u00fajo-Andrade","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department, S\u00e3o Jo\u00e3o Hospital, S\u00e3o Jo\u00e3o Local Health Unit, Porto, Portugal;"},{"name":"Biomedicine Department \u2013 Anatomy Unit, Faculty of Medicine of the University of Porto, Porto, Portugal;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Conde de Bertiandos Hospital, Alto Minho Local Health Unit, Ponte de Lima, Portugal;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diogo","family":"Silva","sequence":"additional","affiliation":[{"name":"Clinical Pathology Department, S\u00e3o Jo\u00e3o Hospital, S\u00e3o Jo\u00e3o Local Health Unit, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipa","family":"Ceia","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department, S\u00e3o Jo\u00e3o Hospital, S\u00e3o Jo\u00e3o Local Health Unit, Porto, Portugal;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lurdes","family":"Santos","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department, S\u00e3o Jo\u00e3o Hospital, S\u00e3o Jo\u00e3o Local Health Unit, Porto, Portugal;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"issue":"3","key":"b1","series-title":"Clin Infect Dis","first-page":"338","article-title":"Nocardia infection in solid organ transplant recipients: A multicenter European case-control study","volume":"63","author":"Coussement","year":"2016"},{"issue":"4","key":"b2","series-title":"Curr Opin Organ Transplant","first-page":"383","article-title":"Update on Nocardia infections in solid-organ transplantation","volume":"25","author":"Saullo","year":"2020"},{"issue":"8","key":"b3","series-title":"Curr Infect Dis Rep","first-page":"27","article-title":"Updates on Nocardia skin and soft tissue infections in solid organ transplantation","volume":"21","author":"Hemmersbach-Miller","year":"2019"},{"key":"b4","series-title":"Med Mycol","first-page":"126","article-title":"Sporotrichosis between 1898 and 2017: The evolution of knowledge on a changeable disease and on emerging etiological agents","volume":"56","author":"Lopes-Bezerra","year":"2018"},{"issue":"2","key":"b5","series-title":"J Fungi (Basel)","first-page":"56","article-title":"Nodular lymphangitis (sporotrichoid lymphocutaneous infections). 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