{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:39:49Z","timestamp":1788482389018,"version":"build-2803163510"},"reference-count":38,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,7]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>Oz virus (OZV) was first isolated from ticks in Japan in 2018, and human infections with OZV were reported in 2023. However, serosurveillance for OZV infections, compared with that for severe fever with thrombocytopenia syndrome (SFTS), is rarely performed among wild animals. We conducted a retrospective study on the epidemiology of SFTS virus and OZV infections in wild animals. Serum samples were collected from 289 deer, 158 raccoons, and 381 wild boars in this study. The positivity rates for the anti-OZV IgG antibody in deer (10.3%), raccoons (12%), and wild boars (12.1%) showed no difference. Both OZV and SFTS virus IgG antibodies were detected in wild animals. Wild animals in Oita Prefecture had anti-OZV antibodies, suggesting that human cases will occur in the future. We recommend educating the public about the tick-borne pathogen risks in this area and implementing tick bite prevention strategies.<\/jats:p>","DOI":"10.4269\/ajtmh.25-0386","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T15:13:24Z","timestamp":1763046804000},"page":"194-196","source":"Crossref","is-referenced-by-count":1,"title":["Wildlife Exposure Rates to Oz Virus vs. Severe Fever with Thrombocytopenia Syndrome Virus in Oita Prefecture, Japan"],"prefix":"10.4269","volume":"114","author":[{"given":"Takehiro","family":"Hashimoto","sequence":"first","affiliation":[{"name":"Hospital Infection Control Center, Oita University Hospital, Oita, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaaki","family":"Yahiro","sequence":"additional","affiliation":[{"name":"Department of Advanced Medical Sciences, Oita University Faculty of Medicine, Oita, Japan;"},{"name":"Department of Microbiology, Oita University Faculty of Medicine, Oita, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minami W.","family":"Okuyama","sequence":"additional","affiliation":[{"name":"Oita University Faculty of Medicine, Oita, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakirul","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oita University Faculty of Medicine, Oita, Japan;"},{"name":"Research Center for Global and Local Infectious Diseases, Oita, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Kimitsuki","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oita University Faculty of Medicine, Oita, Japan;"},{"name":"Research Center for Global and Local Infectious Diseases, Oita, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazufumi","family":"Hiramatsu","sequence":"additional","affiliation":[{"name":"Hospital Infection Control Center, Oita University Hospital, Oita, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Nishizono","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oita University Faculty of Medicine, Oita, Japan;"},{"name":"Research Center for Global and Local Infectious Diseases, Oita, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Virus Res","first-page":"57","article-title":"Characterization of a novel Thogotovirus isolated from Amblyomma testudinarium ticks in Ehime, Japan: A significant phylogenetic relationship to Bourbon virus","volume":"249","author":"Ejiri","year":"2018"},{"key":"b2","series-title":"Ann Trop Med Parasitol","first-page":"49","article-title":"Arthropod-borne viral infections of man in Nigeria, 1964\u20131970","volume":"69","author":"Moore","year":"1975"},{"key":"b3","series-title":"Vopr Virusol","first-page":"724","article-title":"Dhori virus\u2014A causative agent of human disease. 5 cases of laboratory infection","volume":"32","author":"Butenko","year":"1987"},{"key":"b4","series-title":"Emerg Infect Dis","first-page":"760","article-title":"Novel Thogotovirus associated with febrile illness and death, United States, 2014","volume":"21","author":"Kosoy","year":"2015"},{"key":"b5","article-title":"Oz Virus Infection in Human","year":"2023"},{"key":"b6","series-title":"Am J Trop Med Hyg","first-page":"1547","article-title":"Distribution of severe fever with thrombocytopenia syndrome virus and antiviral antibodies in wild and domestic animals in Oita Prefecture, Japan","volume":"106","author":"Hashimoto","year":"2022"},{"key":"b7","series-title":"Emerg Infect Dis","first-page":"436","article-title":"Zoonotic infection with Oz virus, a novel Thogotovirus","volume":"28","author":"Tran","year":"2022"},{"key":"b8","series-title":"Mem Inst Oswaldo Cruz","first-page":"501","article-title":"Calculation of the ELISA\u2019s cut-off based on the change-point analysis method for detection of Trypanosoma cruzi infection in Bolivian dogs in the absence of controls","volume":"111","author":"Lardeux","year":"2016"},{"key":"b9","series-title":"Emerg Infect Dis","first-page":"720","article-title":"Oz virus infection in 6 animal species, including macaques, bears, and companion animals, Japan","volume":"31","author":"Matsuu","year":"2025"},{"key":"b10","series-title":"J Vet Med Sci","first-page":"982","article-title":"Roles of raccoons in the transmission cycle of severe fever with thrombocytopenia syndrome virus","volume":"84","author":"Tatemoto","year":"2022"},{"key":"b11","series-title":"Ticks Tick Borne Dis","first-page":"102115","article-title":"Seroprevalence of severe fever with thrombocytopenia syndrome virus in medium-sized wild mammals in Miyazaki, Japan","volume":"14","author":"Kaneko","year":"2023"},{"key":"b12","series-title":"JMA J","first-page":"295","article-title":"Severe fever with thrombocytopenia syndrome: Japan under threat from life-threatening emerging tick-borne disease","volume":"3","author":"Crump","year":"2020"},{"key":"b13","series-title":"Pathogens","first-page":"116","article-title":"Tick diversity and distribution of pathogen in ticks collected from wild animals and vegetation in Africa","volume":"14","author":"Yessinou","year":"2025"},{"key":"b14","series-title":"Vet Med Sci","first-page":"877","article-title":"Serological and molecular survey of tick-borne zoonotic pathogens including severe fever with thrombocytopenia syndrome virus in wild boars in Miyazaki Prefecture, Japan","volume":"8","author":"Kirino","year":"2022"},{"key":"b15","series-title":"Intern Med","first-page":"2861","article-title":"Tick-borne disease with Yezo virus and Borrelia miyamotoi coinfection","volume":"63","author":"Suzuki","year":"2024"},{"key":"b16","series-title":"J Infect Chemother","first-page":"333","article-title":"The first case of imported Borrelia miyamotoi disease concurrent with Lyme disease","volume":"23","author":"Oda","year":"2017"},{"key":"b17","series-title":"Open Forum Infect Dis","first-page":"ofad377","article-title":"Coinfection with severe fever with thrombocytopenia syndrome and scrub typhus in Korea","volume":"10","author":"Chatterjee","year":"2023"},{"key":"b18","series-title":"J Infect Chemother","first-page":"802","article-title":"Seroprevalence of severe fever with thrombocytopenia syndrome (SFTS) virus antibodies in humans and animals in Ehime prefecture, Japan, an endemic region of SFTS","volume":"24","author":"Kimura","year":"2018"},{"key":"b19","series-title":"Vet Med Sci","first-page":"600","article-title":"A retrospective survey of the seroprevalence of severe fever with thrombocytopenia syndrome virus in wild animals in Japan","volume":"7","author":"Okada","year":"2021"},{"key":"b1","series-title":"Virus Res","first-page":"57","article-title":"Characterization of a novel Thogotovirus isolated from Amblyomma testudinarium ticks in Ehime, Japan: A significant phylogenetic relationship to Bourbon virus","volume":"249","author":"Ejiri","year":"2018"},{"key":"b2","series-title":"Ann Trop Med Parasitol","first-page":"49","article-title":"Arthropod-borne viral infections of man in Nigeria, 1964\u20131970","volume":"69","author":"Moore","year":"1975"},{"key":"b3","series-title":"Vopr Virusol","first-page":"724","article-title":"Dhori virus\u2014A causative agent of human disease. 5 cases of laboratory infection","volume":"32","author":"Butenko","year":"1987"},{"key":"b4","series-title":"Emerg Infect Dis","first-page":"760","article-title":"Novel Thogotovirus associated with febrile illness and death, United States, 2014","volume":"21","author":"Kosoy","year":"2015"},{"key":"b5","article-title":"Oz Virus Infection in Human","year":"2023"},{"key":"b6","series-title":"Am J Trop Med Hyg","first-page":"1547","article-title":"Distribution of severe fever with thrombocytopenia syndrome virus and antiviral antibodies in wild and 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virus","volume":"84","author":"Tatemoto","year":"2022"},{"key":"b11","series-title":"Ticks Tick Borne Dis","first-page":"102115","article-title":"Seroprevalence of severe fever with thrombocytopenia syndrome virus in medium-sized wild mammals in Miyazaki, Japan","volume":"14","author":"Kaneko","year":"2023"},{"key":"b12","series-title":"JMA J","first-page":"295","article-title":"Severe fever with thrombocytopenia syndrome: Japan under threat from life-threatening emerging tick-borne disease","volume":"3","author":"Crump","year":"2020"},{"key":"b13","series-title":"Pathogens","first-page":"116","article-title":"Tick diversity and distribution of pathogen in ticks collected from wild animals and vegetation in Africa","volume":"14","author":"Yessinou","year":"2025"},{"key":"b14","series-title":"Vet Med Sci","first-page":"877","article-title":"Serological and molecular survey of tick-borne zoonotic pathogens including severe fever with thrombocytopenia syndrome virus in wild boars in Miyazaki Prefecture, Japan","volume":"8","author":"Kirino","year":"2022"},{"key":"b15","series-title":"Intern Med","first-page":"2861","article-title":"Tick-borne disease with Yezo virus and Borrelia miyamotoi coinfection","volume":"63","author":"Suzuki","year":"2024"},{"key":"b16","series-title":"J Infect Chemother","first-page":"333","article-title":"The first case of imported Borrelia miyamotoi disease concurrent with Lyme disease","volume":"23","author":"Oda","year":"2017"},{"key":"b17","series-title":"Open Forum Infect Dis","first-page":"ofad377","article-title":"Coinfection with severe fever with thrombocytopenia syndrome and scrub typhus in Korea","volume":"10","author":"Chatterjee","year":"2023"},{"key":"b18","series-title":"J Infect Chemother","first-page":"802","article-title":"Seroprevalence of severe fever with thrombocytopenia syndrome (SFTS) virus antibodies in humans and animals in Ehime prefecture, Japan, an endemic region of SFTS","volume":"24","author":"Kimura","year":"2018"},{"key":"b19","series-title":"Vet Med Sci","first-page":"600","article-title":"A retrospective survey of the seroprevalence of severe fever with thrombocytopenia syndrome virus in wild animals in Japan","volume":"7","author":"Okada","year":"2021"}],"container-title":["The American Journal of Tropical Medicine and 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