{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:32:55Z","timestamp":1787031175688,"version":"build-2736575974"},"reference-count":25,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    Yemen is facing an alarming measles outbreak, which represents a significant public health challenge exacerbated by factors such as low vaccination rates. In the present study, the aim was to determine the proportion of patients with measles infection and describe the characteristics of patients who attended Motherhood and Childhood Teaching Hospital in Amran Governorate between January and December 2024. A retrospective cross-sectional study design was used to analyze existing medical records. Among the 6,241 hospital admissions in 2024, 3.78% (\n                    <jats:italic>N<\/jats:italic>\n                    = 236) were clinically diagnosed measles cases. Among these measles patients, 221 of 236 (93.6%) were unvaccinated. Among the 15 vaccinated children, ages ranged from 0.91 to 6 years (the majority were aged 1\u20134 years), with six having received one dose and nine having received two doses. Analysis of the age distribution revealed that a significant proportion of cases occurred in infants under 9 months of age (54\/236, 22.8%) who were ineligible for the first routine vaccine dose. The highest burden was among children aged 2\u20134 years (66\/236, 27.9%). Two deaths (0.8% case fatality rate) occurred in children under 5 years of age because of measles complications. The high proportion of unvaccinated individuals among measles cases highlights significant gaps in vaccination coverage, particularly when compared with national estimates, suggesting overall measles immunization coverage of \u223c41%. This situation is likely compounded by parental misconceptions regarding the importance of vaccination and insufficient awareness of their children\u2019s health needs. To prevent recurring measles infections, raising awareness among parents about the importance of vaccination and encouraging adherence to routine immunization schedules at health facilities are crucial.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.25-0387","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T16:52:53Z","timestamp":1761151973000},"page":"1406-1410","source":"Crossref","is-referenced-by-count":1,"title":["Measles Outbreak in Amran Governorate, Yemen (2024): A Retrospective Study Highlighting Vaccination Gaps"],"prefix":"10.4269","volume":"113","author":[{"given":"Khalid Mohammed","family":"Al-Dhayani","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Amran University, Amran City, Yemen"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Measles","year":"2024"},{"key":"b2","series-title":"Vaccines (Basel)","first-page":"1349","article-title":"Progress of measles and rubella surveillance in the context of measles elimination in the WHO Eastern Mediterranean Region, 2019\u20132022","volume":"12","author":"Farid","year":"2024"},{"key":"b3","series-title":"Measles Cases Surge Worldwide, Infecting 10.3 Million People in 2023","year":"2024"},{"key":"b4","series-title":"Yemen: Immunization Coverage and Reported Measles Cases: WHO Immunization Data Portal","year":"2025"},{"key":"b5","series-title":"Immunize for Life: Yemen Marks World Immunization Week 2025","year":"2025"},{"key":"b6","series-title":"Int J Gen Med","first-page":"1203","article-title":"Trend of measles outbreak in Yemen from January 2020 to August 2024","volume":"18","author":"Edrees","year":"2025"},{"key":"b7","series-title":"Rubella country slides: epidemiological analysis and incidence (PowerPoint): WHO Immunization Data Portal","year":"2025"},{"key":"b8","series-title":"Vaccination in Yemen: Saving Lives, Protecting the Economy","year":"2024"},{"key":"b9","series-title":"Yemen\u2019s Rising Tide of Malnutrition: Seasonal Trends 2022\u20132024: Thematic Report","year":"2025"},{"key":"b10","series-title":"Local Governance in Amran, Yemen \u2013 Maps, Data and Resources","year":"2023"},{"key":"b11","series-title":"Amran Governorate [Archives:2004\/755\/Last Page].","year":"2004"},{"key":"b12","series-title":"Measles Outbreak Guide","year":"2022"},{"key":"b13","series-title":"BMJ Qual Saf","first-page":"986","article-title":"SQUIRE 2.0 (Standards for QUality Improvement Reporting Excellence): revised publication guidelines from a detailed consensus process","volume":"25","author":"Ogrinc","year":"2016"},{"key":"b14","series-title":"Alarming Rise of Measles in Yemen Requires Urgent and Comprehensive Response [EN\/AR].","year":"2023"},{"key":"b15","series-title":"Causes and Impact of Low Vaccination Rates in Yemen.","year":"2023"},{"key":"b16","series-title":"Measles Outbreak Investigation in Qufl Shamr, Hajja Governorate, Yemen, 2012: First National Y-FETP Conference 26-27 Feb 2014, p. 71","author":"Alnajjar","year":"2014"},{"key":"b17","series-title":"BMC Infect Dis","first-page":"358","article-title":"Gender differences in measles incidence rates in a multiyear, pooled analysis, based on national data from seven high income countries","volume":"22","author":"Green","year":"2022"},{"key":"b18","series-title":"Yemen J Med","first-page":"44","article-title":"Risk factors for measles outbreak in Al-Dali governorate, Yemen","volume":"2","author":"Hamood","year":"2023"},{"key":"b19","series-title":"JMIR Public Health Surveill","first-page":"e14461","article-title":"The impact of war in Yemen on immunization coverage of children under one year of age: Descriptive study","volume":"5","author":"Torbosh","year":"2019"},{"key":"b20","series-title":"Measles Outbreak in Sa\u2019adah Governorate, Yemen, 6th \u2013 10th of March 2015: 2nd Y-FETP National Conference 29 Feb 2016, p. 51.","author":"Dehnan"},{"key":"b21","series-title":"Measles Outbreak at Al Zeliah Village, Al Hudaydah Governorate, Yemen, November 2014, 2nd Y-FETP National Conference 29 Feb 2016, p. 50.","author":"Al Amad"},{"key":"b22","series-title":"BMJ Glob Health","first-page":"e011861","article-title":"Lessons learned from applying the Centers for Disease Control and Prevention (CDC) evaluation framework to the measles incidence management system response, USA, 2020\u20132021","volume":"8","author":"Jacenko","year":"2023"},{"key":"b23","series-title":"Lancet Glob Health","first-page":"e451","article-title":"Ongoing threat of a large-scale measles outbreak in Yemen","volume":"4","author":"Qirbi","year":"2016"},{"key":"b24","series-title":"Global Progress against Measles Threatens amidst the COVID-19 Pandemic","year":"2021"},{"key":"b25","series-title":"BMC Public Health","first-page":"239","article-title":"A retrospective analysis of the malaria trend in Yemen over the sixteen-years, from 2006\u20132021","volume":"25","author":"Edrees","year":"2025"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/6\/article-p1406.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/6\/article-p1406.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/6\/article-p1406.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T13:33:05Z","timestamp":1764768785000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/6\/article-p1406.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,3]]},"references-count":25,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.25-0387","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,3]]}}}