{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T16:13:26Z","timestamp":1767802406868,"version":"3.49.0"},"reference-count":10,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,7]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>A 55-year-old male from El Salvador presented to an emergency department in the northeastern United States with diarrhea, vomiting, dizziness, and melena. Shortly after arrival, the patient\u2019s heart rate increased to 235 beats\/min with a narrow QRS complex, which subsequently degenerated into a wide complex ventricular tachycardia (VT). Initial workup revealed severe transaminitis, reduced systolic function, and an anomalous right coronary artery. After extensive diagnostic workup, including cardiac magnetic resonance imaging and serologies, a diagnosis of Chagas cardiomyopathy was made. Given the presence of arrhythmogenic substrate and a high Rassi score for sudden cardiac death, the patient underwent placement of an implantable cardioverter-defibrillator (ICD) for secondary prevention of VT. This case underscores the increasing importance of considering Chagas disease in patients in the United States coming from endemic countries and the decision-making process regarding ICD placement in a patient with underlying Chagas-related cardiomyopathy.<\/jats:p>","DOI":"10.4269\/ajtmh.25-0447","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T15:13:23Z","timestamp":1763046803000},"page":"108-110","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Sudden Cardiac Arrest Due to Chagas Disease: Management and Decision for Implantable Cardioverter-Defibrillator Placement"],"prefix":"10.4269","volume":"114","author":[{"given":"Holden","family":"Caplan","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Maryland Medical Center, Baltimore, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trent","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, University of Maryland Medical Center, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manu","family":"Mysore","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, University of Maryland Medical Center, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Emerg Infect Dis","first-page":"1313","article-title":"Updated estimates and mapping for prevalence of Chagas disease among adults, United States","volume":"28","author":"Irish","year":"2022"},{"key":"b2","series-title":"PLoS Negl Trop Dis","first-page":"e0006567","article-title":"Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis","volume":"12","author":"Rojas","year":"2018"},{"key":"b3","series-title":"N Engl J Med","first-page":"1295","article-title":"Randomized trial of benznidazole for Chronic Chagas\u2019 cardiomyopathy","volume":"373","author":"Morillo","year":"2015"},{"key":"b4","series-title":"N Engl J Med","first-page":"799","article-title":"Development and validation of a risk score for predicting death in Chagas\u2019 heart disease","volume":"355","author":"Rassi","year":"2006"},{"key":"b5","series-title":"Circulation","first-page":"e210","article-title":"AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death","volume":"138","author":"Al-Khatib","year":"2018"},{"key":"b1","series-title":"Emerg Infect Dis","first-page":"1313","article-title":"Updated estimates and mapping for prevalence of Chagas disease among adults, United States","volume":"28","author":"Irish","year":"2022"},{"key":"b2","series-title":"PLoS Negl Trop Dis","first-page":"e0006567","article-title":"Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis","volume":"12","author":"Rojas","year":"2018"},{"key":"b3","series-title":"N Engl J Med","first-page":"1295","article-title":"Randomized trial of benznidazole for Chronic Chagas\u2019 cardiomyopathy","volume":"373","author":"Morillo","year":"2015"},{"key":"b4","series-title":"N Engl J Med","first-page":"799","article-title":"Development and validation of a risk score for predicting death in Chagas\u2019 heart disease","volume":"355","author":"Rassi","year":"2006"},{"key":"b5","series-title":"Circulation","first-page":"e210","article-title":"AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death","volume":"138","author":"Al-Khatib","year":"2018"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/114\/1\/article-p108.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/114\/1\/article-p108.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/114\/1\/article-p108.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T13:52:52Z","timestamp":1767793972000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/114\/1\/article-p108.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,7]]},"references-count":10,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.25-0447","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,7]]}}}