{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T21:08:19Z","timestamp":1781816899083,"version":"3.54.5"},"reference-count":46,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    Rare cases of aphthous ulceration and eosinophilic enteritis in humans caused by\n                    <jats:italic>Ancylostoma caninum<\/jats:italic>\n                    (\n                    <jats:italic>A. caninum<\/jats:italic>\n                    ), a common intestinal nematode of dogs worldwide, have been reported over the past century in several regions of the world. The present report involves a case of aphthous ulceration of the colon caused by\n                    <jats:italic>A. caninum<\/jats:italic>\n                    in Western Australia. The identity of the worm recovered during routine colonoscopy of a 35-year-old immunocompetent male was confirmed via morphological analysis and sequencing of the mitochondrial cytochrome c oxidase subunit I gene and nuclear ribosomal internal transcriber spacer II region. A summary of this case and previous reports of human\n                    <jats:italic>A. caninum<\/jats:italic>\n                    intestinal infection is provided. Intestinal infection with\n                    <jats:italic>A. caninum<\/jats:italic>\n                    is likely an underdiagnosed zoonosis in tropical and temperate regions worldwide. Further epidemiological studies and increased clinical awareness of zoonotic hookworms in humans are warranted to clarify the prevalence and significance of\n                    <jats:italic>A. caninum<\/jats:italic>\n                    infection in human hosts.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.25-0592","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T15:35:44Z","timestamp":1770737744000},"page":"672-676","source":"Crossref","is-referenced-by-count":1,"title":["Human Intestinal Infection with the Dog Hookworm, Ancylostoma caninum, in Western Australia"],"prefix":"10.4269","volume":"114","author":[{"given":"Richard S.","family":"Bradbury","sequence":"first","affiliation":[{"name":"James Cook University, Townsville, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patsy A.","family":"Zendejas-Heredia","sequence":"additional","affiliation":[{"name":"Faculty of Science, University of Melbourne, Parkville, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Truarn","sequence":"additional","affiliation":[{"name":"Enteric Disease Reference Laboratory, PathWest Laboratory Medicine WA, Perth, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Bradford","sequence":"additional","affiliation":[{"name":"Enteric Disease Reference Laboratory, PathWest Laboratory Medicine WA, Perth, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Briony","family":"Hazelton","sequence":"additional","affiliation":[{"name":"Enteric Disease Reference Laboratory, PathWest Laboratory Medicine WA, Perth, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duy","family":"Pham","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Sir Charles Gardner Hospital, Perth, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harsha","family":"Sheorey","sequence":"additional","affiliation":[{"name":"Department of Microbiology, St. Vincent\u2019s Hospital, Melbourne and Royal Melbourne Hospital, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vito","family":"Colella","sequence":"additional","affiliation":[{"name":"Faculty of Science, University of Melbourne, Parkville, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Int J Parasitol","first-page":"1233","article-title":"Zoonotic hookworms of dogs and cats\u2013Lessons from the past to inform current knowledge and future directions of research","volume":"51","author":"Traub","year":"2021"},{"key":"b2","series-title":"Gastroenterology","first-page":"3","article-title":"Occult enteric infection by Ancylostoma caninum: A previously unrecognized zoonosis","volume":"106","author":"Croese","year":"1994"},{"key":"b3","series-title":"Ann Intern Med","first-page":"369","article-title":"Human enteric infection with canine hookworms","volume":"120","author":"Croese","year":"1994"},{"key":"b4","series-title":"Transactions of the 6th Congress of the Far Eastern Association of Tropical Medicine","first-page":"351","author":"Manalang","year":"1925"},{"key":"b5","series-title":"Rev. Clin. Sao Paulo","first-page":"235","article-title":"Do Sabre dois casos de parasitismo do homen pelo Ancylostoma caninum (Ercolani, 1859) Hall, 1913","volume":"16","author":"Barretto","year":"1944"},{"key":"b6","series-title":"Chinese Med J","first-page":"130","article-title":"Occurrence of Dog Hookworm (Ancylostoma caninum) In Man","volume":"63A","author":"Mao","year":"1945"},{"key":"b7","series-title":"Revista Do Servi\u00e7o Especial de Sa\u00fade P\u00fablica","first-page":"443","article-title":"Helmintos eliminados por um grupo de residentes do Amazonas ap\u00f3s tratamento com Hexilresorcinol","volume":"3","author":"Deane","year":"1950"},{"key":"b8","series-title":"Medisch Maandblad","first-page":"165","article-title":"Enkele bijzondere worm infecties uit Indonesi\u00eb","volume":"3","author":"Joe","year":"1950"},{"key":"b9","series-title":"Harefuah","first-page":"178","article-title":"Some unusual observations on helminthiasis in Israel","volume":"41","author":"Witenberg","year":"1951"},{"key":"b10","series-title":"Rev Goiana Med","first-page":"169","article-title":"Collection of ancylostomes from, and their prevalence in, 14 natives of Goiania: A case infected by Ancylostoma caninum.","volume":"15","author":"Komma","year":"1969"},{"key":"b11","series-title":"Am J Surg Pathol","first-page":"328","article-title":"Eosinophilic enteritis in northeastern Australia: Pathology, association with Ancylostoma caninum, and implications","volume":"19","author":"Walker","year":"1995"},{"key":"b12","series-title":"Rev Soc Bras Med Trop","first-page":"57","article-title":"Infesta\u00e7\u00e3o do intestino humano pelo Ancylostoma caninum Ercolani, 1859","volume":"18","author":"Carias","year":"1985"},{"key":"b13","series-title":"Emerg Infect Dis","first-page":"181","article-title":"Rare case of enteric Ancylostoma caninum hookworm infection, South Korea","volume":"26","author":"Jung","year":"2020"},{"key":"b14","series-title":"Nucleic Acids Res","first-page":"2525","article-title":"Rapid sequencing of rDNA from single worms and eggs of parasitic helminths","volume":"21","author":"Gasser","year":"1993"},{"key":"b15","series-title":"Int J Parasitol","first-page":"1965","article-title":"NADH dehydrogenase subunit 1 and cytochrome c oxidase subunit I sequences compared for members of the genus Taenia (Cestoda)","volume":"29","author":"Gasser","year":"1999"},{"key":"b16","series-title":"Acta Trop","first-page":"23","article-title":"Human enteric infection with Ancylostoma caninum: Hookworms reappraised in the light of a \u201cnew\u201d zoonosis","volume":"62","author":"Prociv","year":"1996"},{"key":"b17","series-title":"Trends Parasitol","first-page":"547","article-title":"Intestinal allergy expels hookworms: Seeing is believing","volume":"22","author":"Croese","year":"2006"},{"key":"b18","series-title":"J Gastroenterol Hepatol","first-page":"524","article-title":"A distinctive aphthous ileitis linked to Ancylostoma caninum.","volume":"11","author":"Croese","year":"1996"},{"key":"b19","series-title":"Med J Aust","first-page":"69","article-title":"Experimental human infection with the dog hookworm, Ancylostoma caninum.","volume":"178","author":"Landmann","year":"2003"},{"key":"b20","series-title":"J Pediatr Gastroenterol Nutr","first-page":"448","article-title":"Dog hookworm: A cause of eosinophilic enterocolitis in humans","volume":"19","author":"Khoshoo","year":"1994"},{"key":"b21","series-title":"J Egypt Soc Parasitol","first-page":"873","article-title":"Evaluation of the role of Ancylostoma caninum in humans as a cause of acute and recurrent abdominal pain","volume":"29","author":"Bahgat","year":"1999"},{"key":"b22","series-title":"Int J Parasitol","first-page":"637","article-title":"Faecal prevalence, distribution and risk factors associated with canine soil-transmitted helminths contaminating urban parks across Australia.","volume":"52","author":"Massetti","year":"2022"},{"key":"b23","series-title":"Neglected Tropical Diseases \u2013 Oceania","first-page":"33","author":"Bradbury","year":"2016"},{"key":"b1","series-title":"Int J Parasitol","first-page":"1233","article-title":"Zoonotic hookworms of dogs and cats\u2013Lessons from the past to inform current knowledge and future directions of research","volume":"51","author":"Traub","year":"2021"},{"key":"b2","series-title":"Gastroenterology","first-page":"3","article-title":"Occult enteric infection by Ancylostoma caninum: A previously unrecognized zoonosis","volume":"106","author":"Croese","year":"1994"},{"key":"b3","series-title":"Ann Intern Med","first-page":"369","article-title":"Human enteric infection with canine hookworms","volume":"120","author":"Croese","year":"1994"},{"key":"b4","series-title":"Transactions of the 6th Congress of the Far Eastern Association of Tropical Medicine","first-page":"351","author":"Manalang","year":"1925"},{"key":"b5","series-title":"Rev. Clin. Sao Paulo","first-page":"235","article-title":"Do Sabre dois casos de parasitismo do homen pelo Ancylostoma caninum (Ercolani, 1859) Hall, 1913","volume":"16","author":"Barretto","year":"1944"},{"key":"b6","series-title":"Chinese Med J","first-page":"130","article-title":"Occurrence of Dog Hookworm (Ancylostoma caninum) In Man","volume":"63A","author":"Mao","year":"1945"},{"key":"b7","series-title":"Revista Do Servi\u00e7o Especial de Sa\u00fade P\u00fablica","first-page":"443","article-title":"Helmintos eliminados por um grupo de residentes do Amazonas ap\u00f3s tratamento com Hexilresorcinol","volume":"3","author":"Deane","year":"1950"},{"key":"b8","series-title":"Medisch Maandblad","first-page":"165","article-title":"Enkele bijzondere worm infecties uit Indonesi\u00eb","volume":"3","author":"Joe","year":"1950"},{"key":"b9","series-title":"Harefuah","first-page":"178","article-title":"Some unusual observations on helminthiasis in Israel","volume":"41","author":"Witenberg","year":"1951"},{"key":"b10","series-title":"Rev Goiana Med","first-page":"169","article-title":"Collection of ancylostomes from, and their prevalence in, 14 natives of Goiania: A case infected by Ancylostoma caninum.","volume":"15","author":"Komma","year":"1969"},{"key":"b11","series-title":"Am J Surg Pathol","first-page":"328","article-title":"Eosinophilic enteritis in northeastern Australia: Pathology, association with Ancylostoma caninum, and implications","volume":"19","author":"Walker","year":"1995"},{"key":"b12","series-title":"Rev Soc Bras Med Trop","first-page":"57","article-title":"Infesta\u00e7\u00e3o do intestino humano pelo Ancylostoma caninum Ercolani, 1859","volume":"18","author":"Carias","year":"1985"},{"key":"b13","series-title":"Emerg Infect Dis","first-page":"181","article-title":"Rare case of enteric Ancylostoma caninum hookworm infection, South Korea","volume":"26","author":"Jung","year":"2020"},{"key":"b14","series-title":"Nucleic Acids Res","first-page":"2525","article-title":"Rapid sequencing of rDNA from single worms and eggs of parasitic helminths","volume":"21","author":"Gasser","year":"1993"},{"key":"b15","series-title":"Int J Parasitol","first-page":"1965","article-title":"NADH dehydrogenase subunit 1 and cytochrome c oxidase subunit I sequences compared for members of the genus Taenia (Cestoda)","volume":"29","author":"Gasser","year":"1999"},{"key":"b16","series-title":"Acta Trop","first-page":"23","article-title":"Human enteric infection with Ancylostoma caninum: Hookworms reappraised in the light of a \u201cnew\u201d zoonosis","volume":"62","author":"Prociv","year":"1996"},{"key":"b17","series-title":"Trends Parasitol","first-page":"547","article-title":"Intestinal allergy expels hookworms: Seeing is believing","volume":"22","author":"Croese","year":"2006"},{"key":"b18","series-title":"J Gastroenterol 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