{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:57:17Z","timestamp":1791385037532,"version":"4.3.3"},"reference-count":23,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,7]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    The first confirmation of chikungunya virus infection in Guinea is reported in the present study. The patient, a 68-year-old woman presumptively diagnosed with malaria and with no history of travel, was identified through a research project focused on the etiologies of febrile illnesses in Guinea. A whole-blood sample from the patient was analyzed using multiplex reverse-transcription polymerase chain reaction, yielding a positive result for chikungunya virus, and was subsequently sequenced. The near-complete genome sequence was most closely related to strains circulating that year in Senegal. The study data are noteworthy because, despite past serological evidence of transmission, active human infection with the chikungunya virus has not previously been observed in Guinea; its emergence is linked to the identification of\n                    <jats:italic>Aedes<\/jats:italic>\n                    vectors in Dalaba. Further clinical and entomological investigations are warranted, along with country-wide genomic surveillance of arboviruses to better understand risk factors that have driven the emergence of chikungunya in Guinea and prevent possible future epidemics.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.25-0736","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:08:38Z","timestamp":1785427718000},"page":"837-840","source":"Crossref","is-referenced-by-count":0,"title":["First Identification of an Autochthonous Case of Chikungunya in Guinea"],"prefix":"10.4269","volume":"115","author":[{"given":"Mamadou Bhoye","family":"Keita","sequence":"first","affiliation":[{"name":"Institut National de Sant\u00e9 Publique, Conakry, Guinea;"},{"name":"D\u00e9partement de Biologie, Facult\u00e9 des Sciences, Universit\u00e9 Gamal Abdel Nasser de Conakry, Conakry, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Faye","sequence":"additional","affiliation":[{"name":"Institut Pasteur de Dakar, Dakar, Senegal;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basala","family":"Traor\u00e9","sequence":"additional","affiliation":[{"name":"Institut National de Sant\u00e9 Publique, Conakry, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahamoud Sama","family":"Cherif","sequence":"additional","affiliation":[{"name":"Institut National de Sant\u00e9 Publique, Conakry, Guinea;"},{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Conakry, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamadou Aliou","family":"Sampou","sequence":"additional","affiliation":[{"name":"Institut National de Sant\u00e9 Publique, Conakry, Guinea;"},{"name":"D\u00e9partement de Biologie, Facult\u00e9 des Sciences et Techniques, Universit\u00e9 de Nz\u00e9r\u00e9kor\u00e9, Nz\u00e9r\u00e9kor\u00e9, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alpha Mahmoud","family":"Barry","sequence":"additional","affiliation":[{"name":"Sant\u00e9 Plus Organisation, Conakry, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoumana Isaac","family":"Traore","sequence":"additional","affiliation":[{"name":"Georgetown University, Washington, District of Columbia, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Ryan-Castillo","sequence":"additional","affiliation":[{"name":"Georgetown University, Washington, District of Columbia, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariama Dalanda","family":"Diallo","sequence":"additional","affiliation":[{"name":"Sant\u00e9 Plus Organisation, Conakry, 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Aminata","family":"Keita","sequence":"additional","affiliation":[{"name":"Institut National de Sant\u00e9 Publique, Conakry, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouctar","family":"Keita","sequence":"additional","affiliation":[{"name":"H\u00f4pital Pr\u00e9fectoral de Dalaba, Dalaba, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdourahmane","family":"Diallo","sequence":"additional","affiliation":[{"name":"H\u00f4pital Pr\u00e9fectoral de Dalaba, Dalaba, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houssainatou","family":"Bah","sequence":"additional","affiliation":[{"name":"Institut National de Sant\u00e9 Publique, Conakry, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoulaye Oury","family":"Barry","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Recherche et Formation BioHafia, D\u00e9partement de Biologie Appliqu\u00e9e, Facult\u00e9 des Sciences et Techniques, Universit\u00e9 de Lab\u00e9, Lab\u00e9, Guinea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahima","family":"Gouressy","sequence":"additional","affiliation":[{"name":"Institut National de Sant\u00e9 Publique, Conakry, Guinea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"DeMarco","sequence":"additional","affiliation":[{"name":"Georgetown University, Washington, District of Columbia, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire J.","family":"Standley","sequence":"additional","affiliation":[{"name":"Georgetown University, Washington, District of Columbia, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"issue":"3","key":"b1","series-title":"J Clin Invest","first-page":"737","article-title":"Chikungunya virus: Epidemiology, replication, disease mechanisms, and prospective intervention strategies","volume":"127","author":"Silva","year":"2017"},{"key":"b2","series-title":"Antiviral Res","first-page":"32","article-title":"Chikungunya: Evolutionary history and recent epidemic spread","volume":"120","author":"Weaver","year":"2015"},{"issue":"12","key":"b3","series-title":"PLoS One","first-page":"e115938","article-title":"First reported chikungunya fever outbreak in the republic of Congo, 2011","volume":"9","author":"Moyen","year":"2014"},{"key":"b4","series-title":"Pediatr Infect Dis J","first-page":"789","article-title":"Chikungunya in children","volume":"34","author":"Syrogiannopoulos","year":"2015"},{"issue":"39","key":"b5","series-title":"Euro Surveill","first-page":"17-00646","article-title":"Detection of a chikungunya outbreak in Central Italy, August to September 2017","volume":"22","author":"Venturi","year":"2017"},{"issue":"5","key":"b6","series-title":"Emerg Infect Dis","first-page":"768","article-title":"Chikungunya virus, Cameroon, 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diagnosis","volume":"26","author":"Ochu","year":"2026"},{"issue":"6","key":"b16","series-title":"Lancet Infect Dis","first-page":"571","article-title":"Ebola virus and malaria parasite positivity: A febrile illness quagmire","volume":"17","author":"Massaquoi","year":"2017"},{"issue":"6","key":"b17","series-title":"PLoS Negl Trop Dis","first-page":"e1649","article-title":"Landscape ecology of sylvatic chikungunya virus and mosquito vectors in southeastern Senegal","volume":"6","author":"Diallo","year":"2012"},{"key":"b18","series-title":"Front Public Health","first-page":"1051754","article-title":"Method comparison for Japanese encephalitis virus detection in samples collected from the Indo-Pacific region","volume":"10","author":"Crispell","year":"2022"},{"issue":"5","key":"b19","series-title":"PLOS Glob Public Health","first-page":"e0001675","article-title":"Metagenomic next-generation sequencing to characterize potential etiologies of nonmalarial fever in a cohort living in a high 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