{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:32:55Z","timestamp":1787031175776,"version":"build-2736575974"},"reference-count":26,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    Oral myiasis is a rare medical condition in which soft tissues of the oral cavity are invaded by the larvae (maggots) of several flies. We report a fatal case in a 75-year-old man from a subtropical rural region of Ecuador who presented to a public health center with respiratory distress, peripheral cyanosis, dyspnea, and a Glasgow Coma Scale score of 9 of 15. The oral cavity emitted a fetid odor and contained bloody secretions with extensive larval invasion affecting the gingiva, lower lip, tongue, and soft palate. More than 300 larvae were manually extracted and morphologically identified as third-instar\n                    <jats:italic>Cochliomyia hominivorax<\/jats:italic>\n                    . The patient had a known history of epilepsy managed with carbamazepine (400 mg\/day). Despite supportive management, including oxygen therapy and fluid resuscitation, the patient died approximately 8 hours after admission. The rapid deterioration was probably owing to airway compromise caused by larval migration toward the oropharynx. This case underscores the importance of prompt diagnosis and aggressive management of oral myiasis in vulnerable elderly individuals.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.25-0779","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T13:32:07Z","timestamp":1776173527000},"page":"1180-1183","source":"Crossref","is-referenced-by-count":1,"title":["Severe Oral Myiasis in an Elderly Man with Epilepsy Caused by the New World Screwworm (Cochliomyia hominivorax) in Subtropical Ecuador"],"prefix":"10.4269","volume":"114","author":[{"given":"Manuel","family":"Calvopi\u00f1a","sequence":"first","affiliation":[{"name":"One Health Research Group, Facultad de Medicina, Universidad De Las Am\u00e9ricas (UDLA), Quito, Ecuador;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Jordan-Guarnizo","sequence":"additional","affiliation":[{"name":"One Health Research Group, Facultad de Medicina, Universidad De Las Am\u00e9ricas (UDLA), Quito, Ecuador;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celida","family":"Galeas","sequence":"additional","affiliation":[{"name":"Centro de Salud de Pedro Vicente Maldonado, Ministerio de Salud P\u00fablica, Pedro Vicente Maldonado, Ecuador;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richar","family":"Rodriguez-Hidalgo","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n en Zoonosis, Universidad Central del Ecuador, Quito, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"issue":"1","key":"b1","series-title":"PLoS Negl Trop Dis","first-page":"e0008001","article-title":"What constitutes a neglected tropical disease?","volume":"14","author":"Hotez","year":"2020"},{"key":"b2","article-title":"Myiasis.","year":"2025"},{"issue":"2","key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e0007858","article-title":"Human myiasis in Ecuador","volume":"14","author":"Calvopina","year":"2020"},{"key":"b4","article-title":"New World Screwworm Outbreak.","year":"2025"},{"issue":"2","key":"b5","series-title":"Transbound Emerg Dis","first-page":"968","article-title":"Epidemiological analysis of the New World screwworm (Cochliomyia hominivorax) in Ecuador","volume":"66","author":"Rodr\u00edguez-Hidalgo","year":"2019"},{"key":"b6","article-title":"Screwworm Myiasis.","author":"Spickler","year":"2025"},{"key":"b7","series-title":"Rev Mex Oftalmol","first-page":"43","article-title":"Orbital myiasis caused by Cochliomyia hominivorax severe in the Andean region of Ecuador","volume":"90","author":"Dom\u00ednguez-Enr\u00edquez","year":"2016"},{"key":"b8","article-title":"Miasis por Larvas de Cochliomyia hominivorax.","year":"2025"},{"key":"b9","article-title":"Manual Terrestre de la OIE. El Gusano Barrenador Del Nuevo Mundo (Cochliomyia Hominivorax) (Coquerel) y El Gusano Barrenador Del Viejo Mundo (Chrysomya Bezziana).","year":"2019"},{"issue":"3","key":"b10","series-title":"Spec Care Dentist","first-page":"e70039","article-title":"Severe palatal myiasis in a young patient with neurological and physical disabilities: A case report","volume":"45","author":"Bahia","year":"2025"},{"issue":"6","key":"b11","series-title":"Br J Oral Maxillofac Surg","first-page":"421","article-title":"Re: Treatment of oral myiasis with ivermectin","volume":"41","author":"Shinohara","year":"2003"},{"issue":"1","key":"b12","series-title":"Clin Microbiol Rev","first-page":"79","article-title":"Myiasis","volume":"25","author":"Francesconi","year":"2012"},{"issue":"4","key":"b13","series-title":"Trop Doct","first-page":"235","article-title":"A unique case of facial burn superinfected with Dermatobia hominis larvae resulting in a bilateral enucleation of the eyes","volume":"44","author":"Pinos","year":"2014"},{"issue":"1","key":"b1","series-title":"PLoS Negl Trop Dis","first-page":"e0008001","article-title":"What constitutes a neglected tropical disease?","volume":"14","author":"Hotez","year":"2020"},{"key":"b2","article-title":"Myiasis.","year":"2025"},{"issue":"2","key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e0007858","article-title":"Human myiasis in Ecuador","volume":"14","author":"Calvopina","year":"2020"},{"key":"b4","article-title":"New World Screwworm Outbreak.","year":"2025"},{"issue":"2","key":"b5","series-title":"Transbound Emerg Dis","first-page":"968","article-title":"Epidemiological analysis of the New World screwworm (Cochliomyia hominivorax) in Ecuador","volume":"66","author":"Rodr\u00edguez-Hidalgo","year":"2019"},{"key":"b6","article-title":"Screwworm Myiasis.","author":"Spickler","year":"2025"},{"key":"b7","series-title":"Rev Mex Oftalmol","first-page":"43","article-title":"Orbital myiasis caused by Cochliomyia hominivorax severe in the Andean region of Ecuador","volume":"90","author":"Dom\u00ednguez-Enr\u00edquez","year":"2016"},{"key":"b8","article-title":"Miasis por Larvas de Cochliomyia hominivorax.","year":"2025"},{"key":"b9","article-title":"Manual Terrestre de la OIE. El Gusano Barrenador Del Nuevo Mundo (Cochliomyia Hominivorax) (Coquerel) y El Gusano Barrenador Del Viejo Mundo (Chrysomya Bezziana).","year":"2019"},{"issue":"3","key":"b10","series-title":"Spec Care Dentist","first-page":"e70039","article-title":"Severe palatal myiasis in a young patient with neurological and physical disabilities: A case report","volume":"45","author":"Bahia","year":"2025"},{"issue":"6","key":"b11","series-title":"Br J Oral Maxillofac Surg","first-page":"421","article-title":"Re: Treatment of oral myiasis with ivermectin","volume":"41","author":"Shinohara","year":"2003"},{"issue":"1","key":"b12","series-title":"Clin Microbiol Rev","first-page":"79","article-title":"Myiasis","volume":"25","author":"Francesconi","year":"2012"},{"issue":"4","key":"b13","series-title":"Trop Doct","first-page":"235","article-title":"A unique case of facial burn superinfected with Dermatobia hominis larvae resulting in a bilateral enucleation of the eyes","volume":"44","author":"Pinos","year":"2014"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/114\/6\/article-p1180.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/114\/6\/article-p1180.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/114\/6\/article-p1180.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:16:10Z","timestamp":1780496170000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/114\/6\/article-p1180.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,3]]},"references-count":26,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.25-0779","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,3]]}}}