{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:19:28Z","timestamp":1792271968052,"version":"4.4.0"},"reference-count":26,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>A cohort of 107 subjects (2019\u20132024) between the ages of 20 and 93 years old with an acute febrile illness after a recent tick bite in Suffolk County, New York, was assessed for infection with Powassan, Heartland, and Bourbon viruses. The available blood samples collected from these subjects were sent to the New York State Department of Health for screening using a plaque-reduction neutralization test. Of the 107 subjects analyzed, two had neutralizing antibodies to Bourbon virus, and one had neutralizing antibodies to Heartland virus. A fourfold rise in neutralizing antibody titer in two of these patients (one Bourbon virus and one Heartland virus) indicated an acute or recent infection with these viruses. No subjects were positive for neutralizing antibodies to Powassan virus. This serologic evidence indicates that these patients were infected with emerging viral tick-borne pathogens and further highlights the need for expanded viral surveillance, clinical testing, and assay development to improve clinical decision-making and inform tick-borne disease epidemiology and vector management.<\/jats:p>","DOI":"10.4269\/ajtmh.26-0012","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T14:24:43Z","timestamp":1778595883000},"page":"140-144","source":"Crossref","is-referenced-by-count":2,"title":["Evidence of Heartland and Bourbon Viruses Transmitted by Ticks in Suffolk County, New York"],"prefix":"10.4269","volume":"115","author":[{"given":"Victoria A.","family":"Bateman","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stony Brook University, Stony Brook, New York, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudline G.","family":"Zamor","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stony Brook University, Stony Brook, New York, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Maczaj","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stony Brook University, Stony Brook, New York, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelina","family":"Blyufer","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stony Brook University, Stony Brook, New York, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles Kyriakos","family":"Vorkas","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stony Brook University, Stony Brook, New York, USA;"},{"name":"Department of Microbiology and Immunology, Stony Brook University, Stony Brook, New York, USA;"},{"name":"Center for Infectious Diseases, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander T.","family":"Ciota","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, State University of New York University at Albany School of Public Health, Albany, New York, USA;"},{"name":"Arbovirus Laboratory, Wadsworth Center, New York State Department of Health, Slingerlands, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan P.","family":"Dupuis","sequence":"additional","affiliation":[{"name":"Arbovirus Laboratory, Wadsworth Center, New York State Department of Health, Slingerlands, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A.","family":"Marcos","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stony Brook University, Stony Brook, New York, USA;"},{"name":"Department of Microbiology and Immunology, Stony Brook University, Stony Brook, New York, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","article-title":"Tickborne Diseases of the United States: A Reference Manual for Health Care Providers, 6th Edition.","year":"2022"},{"issue":"9","key":"b2","series-title":"Viruses","first-page":"498","article-title":"Heartland virus epidemiology, vector association, and disease potential","volume":"10","author":"Brault","year":"2018"},{"issue":"2","key":"b3","series-title":"Clin Microbiol Rev","first-page":"e00083-18","article-title":"Emerging tick-borne diseases","volume":"33","author":"Madison-Antenucci","year":"2020"},{"issue":"7","key":"b4","series-title":"Emerg Infect Dis","first-page":"1548","article-title":"Heartland virus in humans and ticks, Illinois, USA, 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