{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:03:51Z","timestamp":1790093031905,"version":"4.0.1"},"reference-count":26,"publisher":"American Society of Tropical Medicine and Hygiene","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,22]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>Bullous pemphigoid is a severe autoimmune blistering disease, and Norwegian scabies is a rare comorbidity. However, conventional treatment methods, such as systemic corticosteroids, carry a high risk in the treatment of elderly patients. Herein, this rare comorbidity is described in an elderly patient. After an initial induction treatment with a low-to-moderate dose of corticosteroid, this patient achieved complete remission with a combination therapy of dupilumab (a monoclonal antibody targeting the interleukin-4\/13 signaling pathway) and ivermectin. Therefore, the successful treatment of this rare case provides a promising strategy for reducing reliance on corticosteroids in high-risk populations.<\/jats:p>","DOI":"10.4269\/ajtmh.26-0186","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:29:14Z","timestamp":1790090954000},"source":"Crossref","is-referenced-by-count":0,"title":["Management of Bullous Pemphigoid and Norwegian Scabies with Dupilumab Plus Ivermectin"],"prefix":"10.4269","author":[{"given":"Yanli","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Dermatology, The Third People\u2019s Hospital of Longgang, Clinical Institute of Shantou University Medical College (The Third People\u2019s Hospital of Longgang District Shenzhen), Shenzhen, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Shenzhen People\u2019s Hospital (The First Affiliated Hospital, Southern University of Science and Technology, The Second Clinical Medical College, Jinan University), Shenzhen, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengan","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Third People\u2019s Hospital of Longgang, Clinical Institute of Shantou University Medical College (The Third People\u2019s Hospital of Longgang District Shenzhen), Shenzhen, China;"},{"name":"Department of Dermatology, Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"issue":"1","key":"b1","series-title":"An Bras Dermatol","first-page":"501266","article-title":"The morbidity of systemic steroids: Analyzing its use in bullous pemphigoid","volume":"101","author":"Nieto-Benito","year":"2026"},{"key":"b2","series-title":"J Dermatol","first-page":"460","article-title":"Comorbid diseases in bullous pemphigoid: A population\u2010based case\u2013control study","volume":"52","author":"Kim","year":"2025"},{"issue":"1","key":"b3","series-title":"Nat Rev Dis Primers","first-page":"12","article-title":"Bullous pemphigoid","volume":"11","author":"Akbarialiabad","year":"2025"},{"key":"b4","series-title":"Front Immunol","first-page":"1196999","article-title":"Comorbidity in bullous pemphigoid: Up-date and clinical implications","volume":"14","author":"Huttelmaier","year":"2023"},{"key":"b5","series-title":"Int Med Case Rep J","first-page":"153","article-title":"Combination of crusted scabies with bullous scabies: A rare case","volume":"16","author":"Asnawi","year":"2023"},{"issue":"1","key":"b6","series-title":"Ital J Pediatr","first-page":"7","article-title":"The hidden scabies: A rare case of atypical Norwegian scabies, case report and literature 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(EADV)","volume":"36","author":"Borradori","year":"2022"},{"issue":"2","key":"b15","series-title":"An Bras Dermatol","first-page":"243","article-title":"Dupilumab, corticosteroids and their combination for the treatment of bullous pemphigoid","volume":"100","author":"Liang","year":"2025"},{"issue":"4","key":"b16","series-title":"Drugs","first-page":"485","article-title":"Autoimmune bullous diseases: Therapeutic update","volume":"86","author":"Kasperkiewicz","year":"2026"},{"issue":"6","key":"b17","series-title":"Clin Dermatol","first-page":"692","article-title":"Advances in the diagnosis of autoimmune bullous dermatoses","volume":"37","author":"Harrell","year":"2019"},{"issue":"2","key":"b18","series-title":"Dermatol Clin","first-page":"321","article-title":"Diagnosis of autoimmune blistering diseases: Dermatopathology and other laboratory updates","volume":"44","author":"Lehman","year":"2026"},{"key":"b19","series-title":"Minerva Pediatr","first-page":"353","article-title":"Successful treatment of Norwegian scabies with ivermectin in a patient with recessive dystrophic epidermolysis bullosa","volume":"56","author":"Angelo","year":"2004"},{"issue":"2","key":"b20","series-title":"Dermatol Rep","first-page":"9751","article-title":"Association of recalcitrant scabies infestation and bullous pemphigoid in an infant","volume":"16","author":"Gambichler","year":"2024"},{"issue":"6","key":"b21","series-title":"Am J Trop Med Hyg","first-page":"1798","article-title":"Bullous scabies: Clinical, dermoscopic, and pathologic characteristics of ten patients","volume":"105","author":"Li","year":"2021"},{"issue":"8","key":"b22","series-title":"JAAD Case Rep","first-page":"722","article-title":"Crusted scabies in a patient with pemphigus vulgaris after treatment with rituximab and corticosteroids","volume":"6","author":"Ashrafzadeh","year":"2020"},{"key":"b23","series-title":"Clin Cosmet Investig Dermatol","first-page":"317","article-title":"Scabies masquerading as bullous pemphigoid: 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