{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:09:17Z","timestamp":1788880157796,"version":"build-2803163510"},"reference-count":34,"publisher":"American Society of Tropical Medicine and Hygiene","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,8]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>To characterize the burden of and identify risk factors for post-coronavirus disease (COVID) condition among high-risk, nonhospitalized patients in Honduras, patients with acute coronavirus disease 2019 (COVID-19) who were discharged from five urban triage facilities were prospectively recruited. These patients were recruited between May and September 2022. Inclusion criteria included a positive COVID-19 antigen test result and either age greater than 60 years or age greater than 45 years with elevated risk for severe COVID-19. Follow-up was conducted at 3 and 4.5 months by telephone. Multivariable logistic regression was used to identify predictors of post-COVID condition. At enrollment, 98% of participants had received two or more doses of the COVID vaccine. Three months after enrollment, 464\/1,133 participants (41%) reported ongoing symptoms. Female sex (adjusted odd ratio [aOR]: 1.68, 95% CI: 1.29\u20132.19), three or more comorbidities (aOR: 1.62, 95% CI: 1.03\u20132.55), and the number of symptoms at enrollment (aOR: 2.41, 95% CI: 1.59\u20133.71 for 7\u20139 symptoms; aOR 3.61, 95% CI: 2.25\u20135.86 for 10 or more symptoms) were predictive of ongoing symptoms. A total of 4.5 months after enrollment, 258\/852 patients (30%) reported ongoing symptoms. Female sex (aOR: 1.82, 95% CI: 1.31\u20132.54), the number of comorbidities (aOR: 1.87, 95% CI: 1.07\u20133.36 for two comorbidities; aOR: 2.38, 95% CI: 1.33\u20134.39 for three or more comorbidities), the number of enrollment symptoms (aOR: 1.73, 95% CI: 1.05\u20132.95 for 7\u20139 symptoms; aOR: 2.59, 95% CI: 1.45\u20134.71 for 10 or more symptoms), and three versus four vaccine doses (aOR: 1.54, 95% CI: 1.06\u20132.22) were predictive of ongoing symptoms. These findings raise concern for an under-recognized burden of post-COVID condition in Honduras. Further research is needed to determine if findings from this high-risk cohort are indicative of post-COVID condition burden among other populations in the region.<\/jats:p>","DOI":"10.4269\/ajtmh.26-0302","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:37:35Z","timestamp":1788878255000},"source":"Crossref","is-referenced-by-count":0,"title":["Post-Coronavirus Disease Condition among Nonhospitalized Patients in Honduras: A Prospective Cohort Study: 2022\u20132023"],"prefix":"10.4269","author":[{"given":"Charles Daniel","family":"Schnorr","sequence":"first","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"},{"name":"Harvard Medical School, Boston, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar Antonio","family":"Diaz Poujol","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salom\u00e9","family":"Garnier","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berta","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn W.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"de St. Aubin","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saul","family":"Cruz","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n General de Redes Integradas de Servicios de Salud, Secretaria de Salud de Honduras, Tegucigalpa, Honduras;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Pavon","sequence":"additional","affiliation":[{"name":"Unidad de Vigilancia de la Salud, Secretaria de Salud de Honduras, Tegucigalpa, Honduras;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Ochoa","sequence":"additional","affiliation":[{"name":"Unidad de Vigilancia de la Salud, Secretaria de Salud de Honduras, Tegucigalpa, Honduras;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Homer Mauricio","family":"Mej\u00eda Santos","sequence":"additional","affiliation":[{"name":"Unidad de Vigilancia de la Salud, Secretaria de Salud de Honduras, Tegucigalpa, Honduras;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yisela","family":"Martinez","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n General de Redes Integradas de Servicios de Salud, Secretaria de Salud de Honduras, Tegucigalpa, Honduras;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonat\u00e1n","family":"Ochoa","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n General de Redes Integradas de Servicios de Salud, Secretaria de Salud de Honduras, Tegucigalpa, Honduras;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Budhwani","sequence":"additional","affiliation":[{"name":"COVID-19 International Task Force, Centers for Disease Control and Prevention, Atlanta, Georgia, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devan","family":"Dumas","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sogeiry","family":"Solis","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Baldwin","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Zielinski Gutierrez","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Central America, Guatemala City, Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiony","family":"Midence","sequence":"additional","affiliation":[{"name":"Unidad de Vigilancia de la Salud, Secretaria de Salud de Honduras, Tegucigalpa, Honduras;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alcides","family":"Martinez","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n General de Redes Integradas de Servicios de Salud, Secretaria de Salud de Honduras, Tegucigalpa, Honduras;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avi","family":"Hakim","sequence":"additional","affiliation":[{"name":"COVID-19 International Task Force, Centers for Disease Control and Prevention, Atlanta, Georgia, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Nilles","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital, Harvard University, Boston, Massachusetts, USA;"},{"name":"Harvard Humanitarian Initiative, Cambridge, Massachusetts, USA;"},{"name":"Harvard Medical School, Boston, Massachusetts, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","article-title":"COVID-19 Cases | WHO COVID-19 Dashboard.","year":"2026"},{"issue":"4","key":"b2","series-title":"Lancet Infect Dis","first-page":"e102","article-title":"A clinical case definition of post-COVID-19 condition by a Delphi 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