{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:56:13Z","timestamp":1790708173590,"version":"4.1.0"},"reference-count":16,"publisher":"American Society of Tropical Medicine and Hygiene","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,29]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>Surgery is the preferable treatment of thoracic cystic echinococcosis (TCE). However, there is no consensus about the best surgical method. Options include lobectomy, segmentectomy, or cystostomy with closure of bronchial openings and capitonnage. The choice depends on cyst integrity, cyst size, number of cysts, location of cysts within the lung, associated lung tissue damage, and treatment costs. Currently, limited data are available on the costs associated with surgical treatment of TCE. We report data from a referral center for TCE in Italy. We collected treatment information and costs for treatment of nine patients with TCE admitted to the Thoracic Surgery Ward at Santi Antonio e Biagio e Cesare Arrigo Hospital in Alessandria, Italy from May 2023 to March 2024. The main surgical approach was cystostomy with closure of bronchial openings and capitonnage. The total expenditures for a single hospitalization, including hospital stay and surgery, ranged from \u20ac9,563.9 to \u20ac29,849 (median: \u20ac13,311.3; interquartile range: \u20ac8,584.75, Q1\u2013Q3: \u20ac11,227.05\u2013\u20ac19,811.80). This study shows the significant variability in treatment cost depending on the surgical technique and clinical complexity.<\/jats:p>","DOI":"10.4269\/ajtmh.26-0308","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:56:59Z","timestamp":1790704619000},"source":"Crossref","is-referenced-by-count":0,"title":["Costs of Surgery for Thoracic Cystic Echinococcosis: Data from a Single Center in Italy"],"prefix":"10.4269","author":[{"given":"Matilde","family":"Pelizzola","sequence":"first","affiliation":[{"name":"Department of Clinical, Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Manciulli","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy;"},{"name":"Department of Integrated Research and Innovation Activity, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Lissandrin","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases I, IRCCS San Matteo Hospital Foundation, Pavia, Italy;"},{"name":"WHO Collaborating Centre for Clinical Management of Cystic Echinococcosis, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Roveta","sequence":"additional","affiliation":[{"name":"Department of Integrated Research and Innovation Activity, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Maconi","sequence":"additional","affiliation":[{"name":"Department of Integrated Research and Innovation Activity, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambra","family":"Vola","sequence":"additional","affiliation":[{"name":"Virology and Microbiology Unit, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy;"},{"name":"Regional Centre for Infectious Diseases (CEREMI), Lombardy Region, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Luca","family":"D\u2019Alessandro","sequence":"additional","affiliation":[{"name":"Emergency Department, Vizzolo Predabissi Hospital, ASST Melegnano-Martesana, Milan, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armanda","family":"Leka","sequence":"additional","affiliation":[{"name":"Department of Clinical, Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Budke","sequence":"additional","affiliation":[{"name":"Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Stocchero","sequence":"additional","affiliation":[{"name":"Department of Clinical, Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Barone","sequence":"additional","affiliation":[{"name":"Department of Clinical, Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Meda","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Brunetti","sequence":"additional","affiliation":[{"name":"Department of Clinical, Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy;"},{"name":"Division of Infectious Diseases I, IRCCS San Matteo Hospital Foundation, Pavia, Italy;"},{"name":"WHO Collaborating Centre for Clinical Management of Cystic Echinococcosis, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy;"},{"name":"Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","article-title":"Ending the Neglect to Attain the Sustainable Development Goals: A Road Map for Neglected Tropical Diseases 2021\u20132030.","year":"2020"},{"key":"b2","series-title":"Adv 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2012","volume":"144","author":"Tamarozzi","year":"2015"},{"issue":"2","key":"b7","series-title":"Am J Trop Med Hyg","first-page":"405","article-title":"Costs associated with surgically treated cases of abdominal cystic echinococcosis: A single center\u2019s experience from 2008 to 2014, Pavia, Italy","volume":"95","author":"Narra","year":"2016"},{"issue":"9","key":"b8","series-title":"J Laparoendosc Adv Surg Tech A","first-page":"882","article-title":"Video-assisted thoracoscopic surgery to treat hydatid disease of the thorax in adults: Is it feasible?","volume":"22","author":"Findikcioglu","year":"2012"},{"issue":"1","key":"b9","series-title":"Ann Thorac Surg","first-page":"258","article-title":"Is video-assisted thoracoscopic surgery adequate in treatment of pulmonary hydatidosis?","volume":"100","author":"Alpay","year":"2015"},{"issue":"8","key":"b10","series-title":"Int J Surg","first-page":"612","article-title":"Pulmonary hydatid disease: What is the optimal surgical strategy?","volume":"8","author":"Nabi","year":"2010"},{"issue":"3","key":"b11","series-title":"Ann Thorac Surg","first-page":"962","article-title":"Capitonnage results in low postoperative morbidity in the surgical treatment of pulmonary echinococcosis","volume":"93","author":"Yaldiz","year":"2012"},{"issue":"3","key":"b12","series-title":"Thorax","first-page":"192","article-title":"Surgical treatment of hydatid cysts of the lung: Report on 1055 patients","volume":"44","author":"Do\u011fan","year":"1989"},{"issue":"7","key":"b13","series-title":"J Pediatr Surg","first-page":"1230","article-title":"Surgical treatment of pulmonary hydatid disease: A comparison of children and adults","volume":"41","author":"Dincer","year":"2006"},{"issue":"11","key":"b14","series-title":"World J Surg","first-page":"1181","article-title":"Surgical treatment for lung hydatid disease","volume":"23","author":"Safioleas","year":"1999"},{"issue":"4","key":"b15","series-title":"Ann Med 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