{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T05:18:05Z","timestamp":1772255885348,"version":"3.50.1"},"reference-count":28,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,2,6]]},"abstract":"<jats:p>We performed a descriptive analysis of acute and potentially life-threatening tropical diseases among 82,825 ill western travelers reported to GeoSentinel from June of 1996 to August of 2011. We identified 3,655 patients (4.4%) with a total of 3,666 diagnoses representing 13 diseases, including falciparum malaria (76.9%), enteric fever (18.1%), and leptospirosis (2.4%). Ninety-one percent of the patients had fever; the median time from travel to presentation was 16 days. Thirteen (0.4%) patients died: 10 with falciparum malaria, 2 with melioidosis, and 1 with severe dengue. Falciparum malaria was mainly acquired in West Africa, and enteric fever was largely contracted on the Indian subcontinent; leptospirosis, scrub typhus, and murine typhus were principally acquired in Southeast Asia. Western physicians seeing febrile and recently returned travelers from the tropics need to consider a wide profile of potentially life-threatening tropical illnesses, with a specific focus on the most likely diseases described in our large case series.<\/jats:p>","DOI":"10.4269\/ajtmh.12-0551","type":"journal-article","created":{"date-parts":[[2013,1,17]],"date-time":"2013-01-17T00:43:24Z","timestamp":1358383404000},"page":"397-404","source":"Crossref","is-referenced-by-count":139,"title":["Acute and Potentially Life-Threatening Tropical Diseases in Western Travelers\u2014A GeoSentinel Multicenter Study, 1996\u20132011"],"prefix":"10.4269","volume":"88","author":[{"given":"Mogens","family":"Jensenius","sequence":"first","affiliation":[]},{"given":"Pauline V.","family":"Han","sequence":"additional","affiliation":[]},{"given":"Patricia","family":"Schlagenhauf","sequence":"additional","affiliation":[]},{"given":"Eli","family":"Schwartz","sequence":"additional","affiliation":[]},{"given":"Philippe","family":"Parola","sequence":"additional","affiliation":[]},{"given":"Francesco","family":"Castelli","sequence":"additional","affiliation":[]},{"given":"Frank","family":"von Sonnenburg","sequence":"additional","affiliation":[]},{"given":"Louis","family":"Loutan","sequence":"additional","affiliation":[]},{"given":"Karin","family":"Leder","sequence":"additional","affiliation":[]},{"given":"David O.","family":"Freedman","sequence":"additional","affiliation":[]}],"member":"2795","reference":[{"key":"R1","series-title":"UNWTO Tourism Highlights, 2010 ed","author":"World Tourism Organization","year":"2010"},{"key":"R2","series-title":"The Greatest Benefit to Mankind. 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