{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T18:48:33Z","timestamp":1770230913887,"version":"3.49.0"},"reference-count":34,"publisher":"Galenos Yayinevi","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mirt"],"DOI":"10.4274\/mirt.galenos.2025.19052","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T10:36:24Z","timestamp":1764326184000},"source":"Crossref","is-referenced-by-count":0,"title":["The Prognostic Significance of Preoperative Staging 18F-FDG PET\/MRI Findings in Gastric Cancer Patients Undergoing Gastrectomy"],"prefix":"10.4274","author":[{"given":"Seda G\u00fclbahar","family":"Ate\u015f","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U\u011furay","family":"Aydos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramazan","family":"Kalkan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00dcmit \u00d6zg\u00fcr","family":"Akdemir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00fctfiye \u00d6zlem","family":"Atay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2811","published-online":{"date-parts":[[2025,11,28]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Sta-tistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209-249.","DOI":"10.3322\/caac.21660"},{"key":"ref1","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1016\/S0140-6736(25)00052-2","article-title":"Gastric cancer","volume":"405","author":"Sundar","year":"2025","unstructured":"2. Sundar R, Nakayama I, Markar SR, Shitara K, van Laarhoven HWM, Janjigian YY, Smyth EC. Gastric cancer. Lancet. 2025;405:2087-2102.","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Ajani JA, D'Amico TA, Bentrem DJ, Corvera CU, Das P, Enzinger PC, Enzler T, Gerdes H, Gibson MK, Grierson P, Gupta G, Hofstetter WL, Ilson DH, Jalal S, Kim S, Kleinberg LR, Klempner S, Lacy J, Lee B, Licciardi F, Lloyd S, Ly QP, Matsukuma K, McNamara M, Merkow RP, Miller AM, Mukherjee S, Mulcahy MF, Perry KA, Pimiento JM, Reddi DM, Reznik S, Roses RE, Strong VE, Su S, Uboha N, Wainberg ZA, Willett CG, Woo Y, Yoon HH, McMillian NR, Stein M. Gastric Cancer, Version 2.2025, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2025;23:","DOI":"10.6004\/jnccn.2025.0022"},{"key":"ref3","unstructured":"169-191."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/j.annonc.2022.07.004","article-title":"Gastric can-cer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","volume":"33","author":"Lordick","year":"2022","unstructured":"4. Lordick F, Carneiro F, Cascinu S, Fleitas T, Haustermans K, Piessen G, Vogel A, Smyth EC; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. Gastric can-cer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol. 2022;33:1005-1020.","journal-title":"Ann Oncol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"20220437","DOI":"10.1259\/bjr.20220437","article-title":"The impact of baseline 18F-FDG PET-CT on the man-agement and outcome of patients with gastric cancer: a systematic review","volume":"95","author":"Foley","year":"2022","unstructured":"5. Foley KG, Coomer W, Coles B, Bradley KM. The impact of baseline 18F-FDG PET-CT on the man-agement and outcome of patients with gastric cancer: a systematic review. Br J Radiol. 2022;95:20220437.","journal-title":"Br J Radiol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1054\/bjoc.2001.1720","article-title":"Pathological serosa and node-based classification accurately predicts gastric cancer recurrence risk and outcome, and determines potential and limitation of a Japanese-style extensive surgery for western pa-tients: a prospective with quality control 10-year follow-up study","volume":"84","author":"Roukos","year":"2001","unstructured":"6. Roukos DH, Lorenz M, Karakostas K, Paraschou P, Batsis C, Kappas AM. Pathological serosa and node-based classification accurately predicts gastric cancer recurrence risk and outcome, and determines potential and limitation of a Japanese-style extensive surgery for western pa-tients: a prospective with quality control 10-year follow-up study. Br J Cancer. 2001;84:1602-1609.","journal-title":"Br J Cancer"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1245\/s10434-006-9218-2","article-title":"Clinical impact of lymphadenectomy extent in resectable gastric can-cer of advanced stage","volume":"14","author":"RE","year":"2007","unstructured":"7. Schwarz RE, Smith DD. Clinical impact of lymphadenectomy extent in resectable gastric can-cer of advanced stage. Ann Surg Oncol. 2007;14:317-328.","journal-title":"Ann Surg Oncol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1007\/BF02573875","article-title":"Recurrence patterns after radical gastrectomy for gastric can-cer: prognostic factors and implications for postoperative adjuvant therapy","volume":"9","author":"Schwarz","year":"2002","unstructured":"8. Schwarz RE, Zagala-Nevarez K. Recurrence patterns after radical gastrectomy for gastric can-cer: prognostic factors and implications for postoperative adjuvant therapy. Ann Surg Oncol. 2002;9:394-400.","journal-title":"Ann Surg Oncol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/S1470-2045(10)70070-X","article-title":"Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial","volume":"11","author":"Songun","year":"2010","unstructured":"9. Songun I, Putter H, Kranenbarg EM, Sasako M, van de Velde CJ. Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial. Lancet On-col. 2010;11:439-449.","journal-title":"Lancet On-col"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1186\/s12885-017-3271-z","article-title":"Prognostic value of pretreatment standardized uptake value of F-18-fluorodeoxyglucose PET in patients with gastric cancer: a meta-analysis","volume":"17","author":"Wu","year":"2017","unstructured":"10. Wu Z, Zhao J, Gao P, Song Y, Sun J, Chen X, Ma B, Wang Z. Prognostic value of pretreatment standardized uptake value of F-18-fluorodeoxyglucose PET in patients with gastric cancer: a meta-analysis. BMC Cancer. 2017;17:275.","journal-title":"BMC Cancer"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1007\/s00330-019-06370-x","article-title":"Gastric cancer and image-derived quantitative parameters: part 2-a critical review of DCE-MRI and 18F-FDG PET\/CT findings","volume":"30","author":"Tang","year":"2020","unstructured":"11. Tang L, Wang XJ, Baba H, Giganti F. Gastric cancer and image-derived quantitative parameters: part 2-a critical review of DCE-MRI and 18F-FDG PET\/CT findings. Eur Radiol. 2020;30:247-260.","journal-title":"Eur Radiol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s40644-025-00871-3","article-title":"PET\/MRI is superior to PET\/CT in detecting oesophago and gastric carcinomas: a meta-analysis","volume":"25","author":"Peng","year":"2025","unstructured":"12. Peng B, Sun H, Hou J, Luo JX. PET\/MRI is superior to PET\/CT in detecting oesophago and gastric carcinomas: a meta-analysis. Cancer Imaging. 2025;25:50.","journal-title":"Cancer Imaging"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"9564627","DOI":"10.1155\/2019\/9564627","article-title":"Comparing PET\/MRI with PET\/CT for pretreatment staging of gastric cancer","volume":"2019","author":"Liu","year":"2019","unstructured":"13. Liu Y, Zheng D, Liu JJ, Cui JX, Xi HQ, Zhang KC, Huang XH, Wei B, Wang XX, Xu BX, Li K, Gao YH, Liang WQ, Tian JH, Chen L. Comparing PET\/MRI with PET\/CT for pretreatment staging of gastric cancer. Gastroenterol Res Pract. 2019;2019:9564627.","journal-title":"Gastroenterol Res Pract"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s40644-020-00317-y","article-title":"Improving MR sequence of 18F-FDG PET\/MR for diagnosing and staging gastric cancer: a comparison study to 18F-FDG PET\/CT","volume":"20","author":"Zheng","year":"2020","unstructured":"14. Zheng D, Liu Y, Liu J, Li K, Lin M, Schmidt H, Xu B, Tian J. Improving MR sequence of 18F-FDG PET\/MR for diagnosing and staging gastric cancer: a comparison study to 18F-FDG PET\/CT. Cancer Imaging. 2020;20:39.","journal-title":"Cancer Imaging"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1016\/j.clon.2022.09.044","article-title":"Respiratory-gated 18F fluorodeoxyglucose positron emission tomography\/magnetic resonance imaging in evaluation of primary gastric lesions and gastric lymph nodes in patients with gastric cancer","volume":"34","author":"G\u00fclbahar Ate\u015f","year":"2022","unstructured":"15. G\u00fclbahar Ate\u015f S, Aydos U, Akdemir \u00dc\u00d6, Y\u00fcksel O, \u00dcner A, Dursun A, Atay L\u00d6. Respiratory-gated 18F fluorodeoxyglucose positron emission tomography\/magnetic resonance imaging in evaluation of primary gastric lesions and gastric lymph nodes in patients with gastric cancer. Clin Oncol (R Coll Radiol). 2022;34:810-818.","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s13139-013-0243-3","article-title":"Pretreatment F-18 FDG PET\/CT pa-rameters to evaluate progression-free survival in gastric cancer","volume":"48","author":"Kim","year":"2014","unstructured":"16. Kim J, Lim ST, Na CJ, Han YH, Kim CY, Jeong HJ, Sohn MH. Pretreatment F-18 FDG PET\/CT pa-rameters to evaluate progression-free survival in gastric cancer. Nucl Med Mol Imaging. 2014;48:33-40.","journal-title":"Nucl Med Mol Imaging"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1007\/s13139-019-00622-w","article-title":"Prognostic value of metabolic information in ad-vanced gastric cancer using preoperative 18F-FDG PET\/CT","volume":"53","author":"Kwon","year":"2019","unstructured":"17. Kwon HR, Pahk K, Park S, Kwon HW, Kim S. Prognostic value of metabolic information in ad-vanced gastric cancer using preoperative 18F-FDG PET\/CT. Nucl Med Mol Imaging. 2019;53:386-395.","journal-title":"Nucl Med Mol Imaging"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"81","DOI":"10.3349\/ymj.2011.52.1.81","article-title":"The role of 18F-FDG PET\/CT in the evaluation of gastric cancer recurrence after curative gastrecto-my","volume":"52","author":"Lee","year":"2011","unstructured":"18. Lee JE, Hong SP, Ahn DH, Jeon TJ, Kang MK, Kwon CI, Ko KH, Hwang SG, Park PW, Rim KS. The role of 18F-FDG PET\/CT in the evaluation of gastric cancer recurrence after curative gastrecto-my. Yonsei Med J. 2011;52:81-88.","journal-title":"Yonsei Med J"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"63968","DOI":"10.18632\/oncotarget.11574","article-title":"Prognostic value of metabol-ic parameters on preoperative 18F-fluorodeoxyglucose positron emission tomogra-phy\/computed tomography in patients with stage III gastric cancer","volume":"7","author":"SJ","year":"2016","unstructured":"19. Na SJ, o JH, Park JM, Lee HH, Lee SH, Song KY, Choi MG, Park CH. Prognostic value of metabol-ic parameters on preoperative 18F-fluorodeoxyglucose positron emission tomogra-phy\/computed tomography in patients with stage III gastric cancer. Oncotarget. 2016;7:63968-63980.","journal-title":"Oncotarget"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"632","DOI":"10.21147\/j.issn.1000-9604.2019.04.07","article-title":"A 18FDG PET\/CT-based volume parameter is a predictor of overall survival in patients with local advanced gastric cancer","volume":"31","author":"Song","year":"2019","unstructured":"20. Song J, Li Z, Chen P, Yu J, Wang F, Yang Z, Wang X. A 18FDG PET\/CT-based volume parameter is a predictor of overall survival in patients with local advanced gastric cancer. Chin J Cancer Res. 2019;31:632-640.","journal-title":"Chin J Cancer Res"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s10238-020-00659-8","article-title":"Intra-tumor metabolic heterogeneity of gastric cancer on 18F-FDG PETCT indicates patient survival outcomes","volume":"21","author":"Liu","year":"2021","unstructured":"21. Liu G, Yin H, Cheng X, Wang Y, Hu Y, Liu T, Shi H. Intra-tumor metabolic heterogeneity of gastric cancer on 18F-FDG PETCT indicates patient survival outcomes. Clin Exp Med. 2021;21:129-138.","journal-title":"Clin Exp Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s10120-018-0847-5","article-title":"The clinical implications of FDG-PET\/CT differ according to histology in advanced gas-tric cancer","volume":"22","author":"Chon","year":"2019","unstructured":"22. Chon HJ, Kim C, Cho A, Kim YM, Jang SJ, Kim BO, Park CH, Hyung WJ, Ahn JB, Noh SH, Yun M, Rha SY. The clinical implications of FDG-PET\/CT differ according to histology in advanced gas-tric cancer. Gastric Cancer. 2019;22:113-122.","journal-title":"Gastric Cancer"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1007\/s00330-018-5732-4","article-title":"Gastric cancer and imaging biomarkers: part 1 - a critical review of DW-MRI and CE-MDCT findings","volume":"29","author":"Giganti","year":"2019","unstructured":"23. Giganti F, Tang L, Baba H. Gastric cancer and imaging biomarkers: part 1 - a critical review of DW-MRI and CE-MDCT findings. Eur Radiol. 2019;29:1743-1753.","journal-title":"Eur Radiol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.radonc.2014.01.004","article-title":"Inte-grating pretreatment diffusion weighted MRI into a multivariable prognostic model for head and neck squamous cell carcinoma","volume":"110","author":"Lambrecht","year":"2014","unstructured":"24. Lambrecht M, Van Calster B, Vandecaveye V, De Keyzer F, Roebben I, Hermans R, Nuyts S. Inte-grating pretreatment diffusion weighted MRI into a multivariable prognostic model for head and neck squamous cell carcinoma. Radiother Oncol. 2014;110:429-434.","journal-title":"Radiother Oncol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1007\/s00595-025-03050-w","article-title":"The minimum apparent diffusion coefficient value on preoperative magnetic resonance imaging in resectable pancreatic cancer: a new prognostic factor for biologically borderline resectable pancreatic cancer","volume":"55","author":"Matsumoto","year":"2025","unstructured":"25. Matsumoto M, Tsunematsu M, Hamura R, Haruki K, Furukawa K, Shirai Y, Uwagawa T, Onda S, Taniai T, Tanji Y, Yanagaki M, Ikegami T. The minimum apparent diffusion coefficient value on preoperative magnetic resonance imaging in resectable pancreatic cancer: a new prognostic factor for biologically borderline resectable pancreatic cancer. Surg Today. 2025;55:1461-1470.","journal-title":"Surg Today"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"118","DOI":"10.21147\/j.issn.1000-9604.2017.02.04","article-title":"Apparent diffusion coefficient by diffusion-weighted magnetic reso-nance imaging as a sole biomarker for staging and prognosis of gastric cancer","volume":"29","author":"Giganti","year":"2017","unstructured":"26. Giganti F, Ambrosi A, Chiari D, Orsenigo E, Esposito A, Mazza E, Albarello L, Staudacher C, Del Maschio A, De Cobelli F. Apparent diffusion coefficient by diffusion-weighted magnetic reso-nance imaging as a sole biomarker for staging and prognosis of gastric cancer. Chin J Cancer Res. 2017;29:118-126.","journal-title":"Chin J Cancer Res"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1148\/radiol.15141900","article-title":"Prognostic role of diffusion-weighted MR imaging for re-sectable gastric cancer","volume":"276","author":"Giganti","year":"2015","unstructured":"27. Giganti F, Orsenigo E, Esposito A, Chiari D, Salerno A, Ambrosi A, Albarello L, Mazza E, Stau-dacher C, Del Maschio A, De Cobelli F. Prognostic role of diffusion-weighted MR imaging for re-sectable gastric cancer. Radiology. 2015;276:444-452.","journal-title":"Radiology"},{"key":"ref28","doi-asserted-by":"publisher","unstructured":"28. Dal Cero M, Bencivenga M, Liu DHW, Sacco M, Alloggio M, Kerckhoffs KGP, Filippini F, Saragoni L, Iglesias M, Tomezzoli A, Carneiro F, Grabsch HI, Verlato G, Torroni L, Piessen G, Pera M, de Manzoni G. Clinical features of gastric signet ring cell cancer: results from a systematic review and meta-analysis. Cancers (Basel). 2023;15.","DOI":"10.3390\/cancers15215191"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1097\/SLA.0b013e3181b21c7b","article-title":"Signet ring cell histology is an in-dependent predictor of poor prognosis in gastric adenocarcinoma regardless of tumoral clini-cal presentation","volume":"250","author":"Piessen","year":"2009","unstructured":"29. Piessen G, Messager M, Leteurtre E, Jean-Pierre T, Mariette C. Signet ring cell histology is an in-dependent predictor of poor prognosis in gastric adenocarcinoma regardless of tumoral clini-cal presentation. Ann Surg. 2009;250:878-887.","journal-title":"Ann Surg"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1097\/SLA.0000000000001793","article-title":"Differential prognostic implications of gastric signet ring cell carcinoma: stage ad-justed analysis from a single high-volume Center in Asia","volume":"265","author":"Chon","year":"2017","unstructured":"30. Chon HJ, Hyung WJ, Kim C, Park S, Kim JH, Park CH, Ahn JB, Kim H, Chung HC, Rha SY, Noh SH, Jeung HC. Differential prognostic implications of gastric signet ring cell carcinoma: stage ad-justed analysis from a single high-volume Center in Asia. Ann Surg. 2017;265:946-953.","journal-title":"Ann Surg"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10120-018-0868-0","article-title":"Consensus on the pathological definition and classification of poorly cohesive gastric carcinoma","volume":"22","author":"Mariette","year":"2019","unstructured":"31. Mariette C, Carneiro F, Grabsch HI, van der Post RS, Allum W, de Manzoni G; European Chapter of International Gastric Cancer Association. Consensus on the pathological definition and classification of poorly cohesive gastric carcinoma. Gastric Cancer. 2019;22:1-9.","journal-title":"Gastric Cancer"},{"key":"ref32","doi-asserted-by":"publisher","unstructured":"32. Song BI, Kim HW, Won KS, Ryu SW, Sohn SS, Kang YN. Preoperative standardized uptake value of metastatic lymph nodes measured by 18F-FDG PET\/CT improves the prediction of prognosis in gastric cancer. Medicine (Baltimore). 2015;94:e1037.","DOI":"10.1097\/MD.0000000000001037"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"218","DOI":"10.5230\/jgc.2018.18.e23","article-title":"Preoperative nodal 18F-FDG avidity rather than primary tumor avidity determines the prognosis of patients with advanced gastric cancer","volume":"18","author":"Kwon","year":"2018","unstructured":"33. Kwon HW, An L, Kwon HR, Park S, Kim S. Preoperative nodal 18F-FDG avidity rather than primary tumor avidity determines the prognosis of patients with advanced gastric cancer. J Gastric Cancer. 2018;18:218-229.","journal-title":"J Gastric Cancer"}],"container-title":["Molecular Imaging and Radionuclide Therapy"],"original-title":[],"deposited":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T06:14:28Z","timestamp":1770185668000},"score":1,"resource":{"primary":{"URL":"https:\/\/mirt.tsnmjournals.org\/articles\/the-prognostic-significance-of-preoperative-staging-lesssupgreater18lesssupgreaterf-fdg-petmri-findings-in-gastric-cancer-patients-undergoing-gastrectomy\/doi\/mirt.galenos.2025.19052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,28]]},"references-count":34,"URL":"https:\/\/doi.org\/10.4274\/mirt.galenos.2025.19052","relation":{},"ISSN":["2146-1414","2147-1959"],"issn-type":[{"value":"2146-1414","type":"print"},{"value":"2147-1959","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,28]]}}}