{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T06:55:19Z","timestamp":1766732119794,"version":"3.48.0"},"reference-count":26,"publisher":"Galenos Yayinevi","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["tjo"],"DOI":"10.4274\/tjo.galenos.2025.82178","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T11:00:00Z","timestamp":1766660400000},"page":"321-328","source":"Crossref","is-referenced-by-count":0,"title":["Anterior Segment OCT Imaging of Bleb Morphological Changes as Predictors of Success After Bleb Needling"],"prefix":"10.4274","volume":"55","author":[{"given":"Abd\u00fclcemal","family":"G\u00fcrp\u0131nar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nur\u015fen","family":"Ar\u0131t\u00fcrk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2811","published-online":{"date-parts":[[2025,12,25]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1111\/ceo.12097","article-title":"Mitomycin C versus 5-fluorouracil as an adjunctive treatment for trabeculectomy: a meta-analysis of randomized clinical trials","volume":"41","author":"De Fendi","year":"2013","unstructured":"1. De Fendi LI, Arruda GV, Scott IU, Paula JS. Mitomycin C versus 5-fluorouracil as an adjunctive treatment for trabeculectomy: a meta-analysis of randomized clinical trials. Clin Exp Ophthalmol. 2013;41:798-806.","journal-title":"Clin Exp Ophthalmol"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2. Liu W, Liu B. Efficacy of anti-vascular endothelial growth factor and mitomycin C on wound healing after trabeculectomy in glaucoma patients: a meta-analysis. Int Wound J. 2024;21:e14517.","DOI":"10.1111\/iwj.14517"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2532","DOI":"10.1016\/j.ophtha.2013.07.049","article-title":"Trabeculectomy in the 21st century: a multicenter analysis","volume":"120","author":"Kirwan","year":"2013","unstructured":"3. Kirwan JF, Lockwood AJ, Shah P, et al. Trabeculectomy in the 21st century: a multicenter analysis. Ophthalmology. 2013;120:2532-2539.","journal-title":"Ophthalmology"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1097\/00061198-200306000-00015","article-title":"Morphologic classification of filtering blebs after glaucoma filtration surgery: the Indiana Bleb Appearance Grading Scale","volume":"12","author":"Cantor","year":"2003","unstructured":"4. Cantor LB, Mantravadi A, WuDunn D, Swamynathan K, Cortes A. Morphologic classification of filtering blebs after glaucoma filtration surgery: the Indiana Bleb Appearance Grading Scale. J Glaucoma. 2003;12:266-271.","journal-title":"J Glaucoma"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Hoffmann EM, Herzog D, Wasielica-Poslednik J, Butsch C, Schuster AK. Bleb grading by photographs versus bleb grading by slit-lamp examination. Acta Ophthalmol. 2020;98:e607-e610.","DOI":"10.1111\/aos.14335"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6. Kudsieh B, Fern\u00e1ndez-Vigo JI, Canut Jordana MI, Vila-Arteaga J, Urcola JA, Ruiz Moreno JM, Garc\u00eda-Feij\u00f3o J, Fern\u00e1ndez-Vigo J\u00c1. Updates on the utility of anterior segment optical coherence tomography in the assessment of filtration blebs after glaucoma surgery. Acta Ophthalmol. 2022;100:e29-e37.","DOI":"10.1111\/aos.14881"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"495","DOI":"10.4103\/ijo.IJO_1130_17","article-title":"Simplifying \"target\" intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma","volume":"66","author":"Sihota","year":"2018","unstructured":"7. Sihota R, Angmo D, Ramaswamy D, Dada T. Simplifying \"target\" intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma. Indian J Ophthalmol. 2018;66:495-505.","journal-title":"Indian J Ophthalmol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"367","DOI":"10.18240\/ijo.2023.03.06","article-title":"Outcomes and risk factors for failure of trabeculectomy in glaucomatous patients in Southwest China: a 325 eyes analysis","volume":"16","author":"Qin","year":"2023","unstructured":"8. Qin ZX, Ying X, Han Q, Wang L, Tan L, Xu YF, You QX, Wu N, Liu Y. Outcomes and risk factors for failure of trabeculectomy in glaucomatous patients in Southwest China: a 325 eyes analysis. Int J Ophthalmol. 2023;16:367-374.","journal-title":"Int J Ophthalmol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1111\/aos.14452","article-title":"Needling after trabeculectomy - does augmentation by anti-metabolites provide better outcomes and is mitomycin C better than 5-fluoruracil? A systematic review with network meta-analyses","volume":"98","author":"Halili","year":"2020","unstructured":"9. Halili A, Kessel L, Subhi Y, Bach-Holm D. Needling after trabeculectomy - does augmentation by anti-metabolites provide better outcomes and is mitomycin C better than 5-fluoruracil? A systematic review with network meta-analyses. Acta Ophthalmol. 2020;98:643-653.","journal-title":"Acta Ophthalmol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"11","DOI":"10.12974\/2309-6136.2023.10.02","article-title":"Internal revision with bleb needling: an effective, safe option for failing blebs","volume":"10","author":"Singh","year":"2023","unstructured":"10. Singh K, Sachdev N, Singh A. Internal revision with bleb needling: an effective, safe option for failing blebs. Journal of Ocular Diseases and Therapeutics. 2023;10:11-15.","journal-title":"Journal of Ocular Diseases and Therapeutics"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"4310258","DOI":"10.1155\/2020\/4310258","article-title":"Safety and efficacy of bleb needling with antimetabolite after trabeculectomy failure in glaucoma patients: a systemic review and meta-analysis","volume":"2020","author":"Chen","year":"2020","unstructured":"11. Chen X, Suo L, Hong Y, Zhang C. Safety and efficacy of bleb needling with antimetabolite after trabeculectomy failure in glaucoma patients: a systemic review and meta-analysis. J Ophthalmol. 2020;2020:4310258.","journal-title":"J Ophthalmol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/S0002-9394(14)76340-8","article-title":"Needle revision with and without 5-fluorouracil for the treatment of failed filtering blebs","volume":"110","author":"RH","year":"1990","unstructured":"12. Ewing RH, Stamper RL. Needle revision with and without 5-fluorouracil for the treatment of failed filtering blebs. Am J Ophthalmol. 1990;110:254-259.","journal-title":"Am J Ophthalmol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"118","DOI":"10.3928\/01913913-20210105-02","article-title":"Outcome of bleb needling with 5-fluorouracil in failed filtering procedures in pediatric glaucoma","volume":"58","author":"Shah","year":"2021","unstructured":"13. Shah C, Sen P, Mohan A, Sen A, Sood D, Jain E. Outcome of bleb needling with 5-fluorouracil in failed filtering procedures in pediatric glaucoma. J Pediatr Ophthalmol Strabismus. 2021;58:118-125.","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1016\/S0002-9394(01)01232-6","article-title":"Risk factors for failure of 5-fluorouracil needling revision for failed conjunctival filtration blebs","volume":"132","author":"Shin","year":"2001","unstructured":"14. Shin DH, Kim YY, Ginde SY, Kim PH, Eliassi-Rad B, Khatana AK, Keole NS. Risk factors for failure of 5-fluorouracil needling revision for failed conjunctival filtration blebs. Am J Ophthalmol. 2001;132:875-880.","journal-title":"Am J Ophthalmol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1016\/j.ophtha.2007.10.023","article-title":"Needling revision of trabeculectomies bleb morphology and long-term survival","volume":"115","author":"AP","year":"2008","unstructured":"15. Rotchford AP, King AJ. Needling revision of trabeculectomies bleb morphology and long-term survival. Ophthalmology. 2008;115:1148-1153.","journal-title":"Ophthalmology"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16. Tsai AS, Boey PY, Htoon HM, Wong TT. Bleb needling outcomes for failed trabeculectomy blebs in Asian eyes: a 2-year follow up. Int J Ophthalmol. 2015;8:748-753.","DOI":"10.1111\/j.1755-3768.2014.T047.x"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"2734","DOI":"10.4103\/ijo.IJO_3506_20","article-title":"Comparison of bleb morphology by anterior segment optical coherence tomography and clinical outcome after phacotrabeculectomy with mitomycin C or Ologen implant","volume":"69","author":"Chelerkar","year":"2021","unstructured":"17. Chelerkar VJ, Agrawal D, S Kalyani VK, Deshpande M. Comparison of bleb morphology by anterior segment optical coherence tomography and clinical outcome after phacotrabeculectomy with mitomycin C or Ologen implant. Indian J Ophthalmol. 2021;69:2734-2739.","journal-title":"Indian J Ophthalmol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1770","DOI":"10.1016\/S0161-6420(95)30795-6","article-title":"An ultrasound biomicroscopic study of filtering blebs after mitomycin C trabeculectomy","volume":"102","author":"Yamamoto","year":"1995","unstructured":"18. Yamamoto T, Sakuma T, Kitazawa Y. An ultrasound biomicroscopic study of filtering blebs after mitomycin C trabeculectomy. Ophthalmology. 1995;102:1770-1776.","journal-title":"Ophthalmology"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"905","DOI":"10.3897\/folmed.63.e58949","article-title":"Confocal microscopy of filtering blebs after trabeculectomy","volume":"63","author":"Kermedchieva","year":"2021","unstructured":"19. Kermedchieva RD, Konareva-Kostianeva M, Mitkova-Hristova V, Atanasov M, Stoyanova NS. Confocal microscopy of filtering blebs after trabeculectomy. Folia Med (Plovdiv). 2021;63:905-912.","journal-title":"Folia Med (Plovdiv)"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"581","DOI":"10.3390\/ph14060581","article-title":"Confocal Microscopy and anterior segment optical coherence tomography \u0131maging of the ocular surface and bleb morphology in medically and surgically treated glaucoma patients: a review","volume":"14","author":"Carnevale","year":"2021","unstructured":"20. Carnevale C, Riva I, Roberti G, Michelessi M, Tanga L, Verticchio Vercellin AC, Agnifili L, Manni G, Harris A, Quaranta L, Oddone F. Confocal Microscopy and anterior segment optical coherence tomography \u0131maging of the ocular surface and bleb morphology in medically and surgically treated glaucoma patients: a review. Pharmaceuticals (Basel). 2021;14:581.","journal-title":"Pharmaceuticals (Basel)"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1136\/bjo.2006.100321","article-title":"Analysis of bleb morphology after trabeculectomy with Visante anterior segment optical coherence tomography","volume":"91","author":"Leung","year":"2007","unstructured":"21. Leung CK, Yick DW, Kwong YY, Li FC, Leung DY, Mohamed S, Tham CC, Chung-chai C, Lam DS. Analysis of bleb morphology after trabeculectomy with Visante anterior segment optical coherence tomography. Br J Ophthalmol. 2007;91:340-344.","journal-title":"Br J Ophthalmol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1016\/j.ophtha.2008.11.019","article-title":"Evaluation of trabeculectomy blebs using 3-dimensional cornea and anterior segment optical coherence tomography","volume":"116","author":"Kawana","year":"2009","unstructured":"22. Kawana K, Kiuchi T, Yasuno Y, Oshika T. Evaluation of trabeculectomy blebs using 3-dimensional cornea and anterior segment optical coherence tomography. Ophthalmology. 2009;116:848-855.","journal-title":"Ophthalmology"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1159\/000260225","article-title":"Bleb needling in encapsulated filtering blebs: evaluation by optical coherence tomography","volume":"224","author":"Guthoff","year":"2009","unstructured":"23. Guthoff R, Guthoff T, Hensler D, Grehn F, Klink T. Bleb needling in encapsulated filtering blebs: evaluation by optical coherence tomography. Ophthalmologica. 2009;224:204-208.","journal-title":"Ophthalmologica"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"24. Lenzhofer M, Strohmaier C, Hohensinn M, Hitzl W, Sperl P, Gerner M, Steiner V, Moussa S, Krall E, Reitsamer HA. Longitudinal bleb morphology in anterior segment OCT after minimally invasive transscleral ab interno Glaucoma Gel Microstent implantation. Acta Ophthalmol. 2019;97:e231-e237.","DOI":"10.1111\/aos.13902"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"280","DOI":"10.3892\/etm.2023.11980","article-title":"Clinical value of anterior segment optical coherence tomographyassisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy","volume":"25","author":"Sun","year":"2023","unstructured":"25. Sun Y, Zhu J, Guo J, He Y, Wang Z. Clinical value of anterior segment optical coherence tomographyassisted Wuerzburg bleb classification system for bleb assessment following trabeculectomy. Exp Ther Med. 2023;25:280.","journal-title":"Exp Ther Med"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1186\/s12886-024-03770-6","article-title":"Discriminatory power of trabeculectomy bleb internal reflectivity and morphology in surgical success using anterior segment optical coherence tomography","volume":"25","author":"Tan","year":"2025","unstructured":"26. Tan JCK, Roney M, Posarelli M, Ansari AS, Batterbury M, Vallabh NA. Discriminatory power of trabeculectomy bleb internal reflectivity and morphology in surgical success using anterior segment optical coherence tomography. BMC Ophthalmol. 2025;25:52.","journal-title":"BMC Ophthalmol"}],"container-title":["Turkish Journal of Ophthalmology"],"original-title":[],"deposited":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T06:50:38Z","timestamp":1766731838000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oftalmoloji.org\/articles\/anterior-segment-oct-imaging-of-bleb-morphological-changes-as-predictors-of-success-after-bleb-needling\/doi\/tjo.galenos.2025.82178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,25]]},"references-count":26,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,12,25]]}},"URL":"https:\/\/doi.org\/10.4274\/tjo.galenos.2025.82178","relation":{},"ISSN":["1300-0659","2147-2661"],"issn-type":[{"type":"print","value":"1300-0659"},{"type":"electronic","value":"2147-2661"}],"subject":[],"published":{"date-parts":[[2025,12,25]]}}}