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Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org; Practice Committee of the American Society for Reproductive Medicine. Prevention and treatment of moderate and severe ovarian hyperstimulation syndrome: a guideline. Fertil Steril 2016;106:1634-47."},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2. Mourad S, Brown J, Farquhar C. Interventions for the prevention of OHSS in ART cycles: an overview of Cochrane reviews. Cochrane Database Syst Rev 2017;1:CD012103.","DOI":"10.1002\/14651858.CD012103.pub2"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Surcel M, Surcel M, Zlatescu-Marton C, Micu R, Nemeti GI, Axente DD, et al. The role of high follicular levels of angiotensin II and vascular endothelial growth factor in antipating the development of severe ovarian hyperstim\u0131lation syndrome in patients with prophylactic cabergoline therapy undergoing an in vitro fertilization procedure. Acta Endocrinol (Buchar) 2020;16:30-6.\u00a0","DOI":"10.4183\/aeb.2020.30"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"4. Duffy DM, Ko C, Jo M, Brannstrom M, Curry TE. Ovulation: Parallels With Inflammatory Processes.\u00a0Endocr Rev\u00a02019;40:369-416.","DOI":"10.1210\/er.2018-00075"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Manau D, Fabregues F, Penarrubia J, Creus M, Carmona F, Casals G, et al. Vascular endothelial growth factor levels in serum and plasma from patients undergoing controlled ovarian hyperstimulation for IVF.\u00a0Hum Reprod\u00a02007;22:669-75.","DOI":"10.1093\/humrep\/del427"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1016\/S0015-0282(98)00484-1","article-title":"The pathogenesis of ovarian hyperstimulation syndrome: in vivo studies investigating the role of interleukin-1beta, interleukin-6, and vascular endothelial growth factor","volume":"71","author":"Pellicer","year":"1999","unstructured":"6. Pellicer A, Albert C, Mercader A, Bonilla-Musoles F, Remoh\u00ed J, Sim\u00f3n C. The pathogenesis of ovarian hyperstimulation syndrome: in vivo studies investigating the role of interleukin-1beta, interleukin-6, and vascular endothelial growth factor. 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