{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T13:48:19Z","timestamp":1771508899240,"version":"3.50.1"},"reference-count":78,"publisher":"Baishideng Publishing Group Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJGP"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4291\/wjgp.v7.i3.266","type":"journal-article","created":{"date-parts":[[2016,8,11]],"date-time":"2016-08-11T21:47:39Z","timestamp":1470952059000},"page":"266","source":"Crossref","is-referenced-by-count":22,"title":["Novel biomarkers of fibrosis in Crohn\u2019s disease"],"prefix":"10.4291","volume":"7","author":[{"given":"Gianluca","family":"Pellino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierlorenzo","family":"Pallante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Selvaggi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw055"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i29.3790"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Bernell O, Lapidus A, Hellers G. Risk factors for surgery and postoperative recurrence in Crohn’s disease. Ann Surg 2000;231:38-45.","DOI":"10.1097\/00000658-200001000-00006"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-006-0150-5"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2014.03.008"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/ng.717"},{"key":"ref7","unstructured":"Dalal SR, Kwon JH. The Role of MicroRNA in Inflammatory Bowel Disease. Gastroenterol Hepatol (NY) 2010;6:714-722."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/ng.175"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1086\/339432"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s100380200067"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.065557"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.35393"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-010-0231-7"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Alvarez-Lobos M, Arostegui JI, Sans M, Tassies D, Plaza S, Delgado S, Lacy AM, Pique JM, Yagüe J, Panés J. Crohn’s disease patients carrying Nod2\/CARD15 gene variants have an increased and early need for first surgery due to stricturing disease and higher rate of surgical recurrence. Ann Surg 2005;242:693-700.","DOI":"10.1097\/01.sla.0000186173.14696.ea"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/path.2277"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2014.09.00"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1136\/gut.47.4.487"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2003.030734"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.03.046"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2003.11.015"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.108043"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21046"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.79"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20368"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.40417.x"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01652.x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2008.04.032"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1136\/gut.30.5.627"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.146357"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.56.11.817"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2009.31"},{"key":"ref32","unstructured":"Loeschke K, Kaltenthaler P. [Procollagen-III-peptide in the serum of patients with Crohn disease]. Z Gastroenterol 1989;27:137-139."},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-002-0446-z"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Di Sabatino A, Ciccocioppo R, Armellini E, Morera R, Ricevuti L, Cazzola P, Fulle I, Corazza GR. Serum bFGF and VEGF correlate respectively with bowel wall thickness and intramural blood flow in Crohn’s disease. Inflamm Bowel Dis 2004;10:573-577.","DOI":"10.1097\/00054725-200409000-00011"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1126\/science.11 9107"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.22934"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2010.01546.x"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-012-2288-z"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1177\/1753425909339231"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21352"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2012.894"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1042\/CS20140048"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12523"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2013.02.020"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-011-1781-0"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.424"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2014.03.009"},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"Yaffe BH, Korelitz BI. Prognosis for nonoperative management of small-bowel obstruction in Crohn’s disease. J Clin Gastroenterol 1983;5:211-215.","DOI":"10.1097\/00004836-198306000-00003"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv207"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.22930"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-012-9890-6"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.13131306"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2015150566"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.113.123919"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.40267.x"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0b013e31829053ce"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000080"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv142"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.3233\/CLO-2009-0503"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1038\/gene.2012.55"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21353"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.00 04496"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00347.2013"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002523"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1734"},{"key":"ref66","doi-asserted-by":"crossref","unstructured":"Wu B, Crampton SP, Hughes CC. Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity 2007;26:227-239.","DOI":"10.1016\/j.immuni.2006.12.007"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1001520107"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1038\/35094067"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2012.150"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.12.001"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv141"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.01.010"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00079.2004"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.10 16\/j.crohns.2013.04.009"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.1097\/01.mog.0000231812.95525.a7"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM19 88090 13190901"},{"key":"ref77","unstructured":"Braakhuis BJ, Tabor MP, Kummer JA, Leemans CR, Brakenhoff RH. A genetic explanation of Slaughter’s concept of field cancerization: evidence and clinical implications. Cancer Res 2003;63:1727-1730."},{"key":"ref78","doi-asserted-by":"crossref","unstructured":"Brentnall TA, Crispin DA, Rabinovitch PS, Haggitt RC, Rubin CE, Stevens AC, Burmer GC. Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis. Gastroenterology 1994;107:369-378.","DOI":"10.1016\/0016-5085(94)90161-9"}],"container-title":["World Journal of Gastrointestinal Pathophysiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/2150-5330\/full\/v7\/i3\/266.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T08:56:45Z","timestamp":1568278605000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/2150-5330\/full\/v7\/i3\/266.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":78,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.4291\/wjgp.v7.i3.266","relation":{},"ISSN":["2150-5330"],"issn-type":[{"value":"2150-5330","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}