{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T04:19:31Z","timestamp":1648873171471},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Afr H. Sci."],"abstract":"<jats:p>Introduction: Pneumocystis jirovecii is the causative organism of Pneumocystis pneumonia (PCP) in humans, which is more common among immunocompromised patients. Classically patients present with fever, non-productive cough, and dyspnoea. In the HIV-infected individuals the symptoms may be subtle at first, but gradually progress over several weeks. In the HIV-uninfected patient, however, the duration of symptoms is shorter and more severe, mainly due to the increased inflammatory response of the HIV-uninfected patient.Methods: This article focuses on the diagnostic methods and then the management and prophylaxis principles of PCP by reviewing the best current practices and guidelines in Africa.Conclusion: This overview is presented by clinicians who have experience with PCP and is directed mainly at first-line healthcare providers.Keywords: Pneumocystis jirovecii pneumonia, african generalist practitioner.<\/jats:p>","DOI":"10.4314\/ahs.v19i4.43","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T10:29:54Z","timestamp":1602584994000},"page":"3200-3207","source":"Crossref","is-referenced-by-count":0,"title":["An overview of Pneumocystis jirovecii pneumonia for the African generalist practitioner"],"prefix":"10.4314","volume":"19","author":[{"given":"I","family":"Govender","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O M","family":"Maphasha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Rangiah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Steyn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2895","published-online":{"date-parts":[[1970,1,1]]},"container-title":["African Health Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/192305\/181429","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/192305\/181429","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T10:30:05Z","timestamp":1602585005000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/view\/192305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,1,1]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,1,17]]}},"URL":"https:\/\/doi.org\/10.4314\/ahs.v19i4.43","relation":{},"ISSN":["1680-6905"],"issn-type":[{"value":"1680-6905","type":"electronic"}],"subject":[],"published":{"date-parts":[[1970,1,1]]}}}