{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:26:34Z","timestamp":1790342794845,"version":"4.1.0"},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Afr H. Sci."],"abstract":"<jats:p>Objective: To analyse the factors influencing clinical pregnancy outcome of in vitro fertilization\/intracytoplasmic sperm injection (IVF\/ICSI) in older women, and to establish a risk prediction model.\r\nMethods: A total of 425 patients receiving IVF\/ICSI from March 2018 to March 2020 were divided into pregnancy group (n=194) and non-pregnancy group (n=231). The factors affecting the outcomes of IVF\/ICSI were explored by univariate and multivariate logistic regression analyses. A nomogram prediction model was constructed.\r\nResults: The two groups had significantly different age, body mass index, dysmenorrhea, parity, times of full-term births, history of cesarean section, basal follicle stimulating hormone, basal antral follicle count (AFC), number of high-quality embryos, and basal estradiol, luteinizing hormone and endometrial thickness on the day of human chorionic gonadotropin (HCG) administration (P&lt;0.05). Age \u226540 years old, dysmenorrhea, history of cesarean section, basal AFC&lt;9, number of high-quality embryos &lt;4, and endometrial thickness on the day of HCG administration &lt;11 mm led to IVF\/ICSI failure. The established model exhibited high calibration and discrimination degrees in predicting the outcome of IVF\/ICSI.\r\nConclusion: The risk prediction model for the pregnancy outcome of IVF\/ICSI in older women helps evaluate the fertility probability and risk, providing references for formulating reasonable assisted reproduction plans.\r\nKeywords: Older pregnant woman; in vitro fertilization\/intracytoplasmic sperm injection; pregnancy outcome; risk factor; nomogram prediction model.<\/jats:p>","DOI":"10.4314\/ahs.v23i2.73","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T14:38:34Z","timestamp":1697121514000},"page":"632-9","source":"Crossref","is-referenced-by-count":2,"title":["Factors influencing clinical pregnancy outcome of in vitro fertilization\/ intracytoplasmic sperm injection in older women"],"prefix":"10.4314","volume":"23","author":[{"given":"Jinyu","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nannan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2895","published-online":{"date-parts":[[2023,7,13]]},"container-title":["African Health Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/250777\/237085","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/250777\/237085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T14:39:07Z","timestamp":1697121547000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/view\/250777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,13]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,7,13]]}},"URL":"https:\/\/doi.org\/10.4314\/ahs.v23i2.73","relation":{},"ISSN":["1729-0503","1680-6905"],"issn-type":[{"value":"1729-0503","type":"electronic"},{"value":"1680-6905","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7,13]]}}}