{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,8]],"date-time":"2025-03-08T05:26:48Z","timestamp":1741411608720,"version":"3.38.0"},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Afr H. Sci."],"abstract":"<jats:p>Background: With most COVID-19 vaccines requiring at least 2 doses, heterologous vaccination will facilitate vaccination programs where vaccine supplies fluctuate. However, with insufficient data on effects of heterologous vaccination in our setting, people remain reluctant to mix.\r\nObjectives: We seek to assess the effects of heterologous vaccination on morbidity and mortality.\r\nMethods: This was a 7 months retrospective study for COVID-19 patients managed by the Bamenda Regional Hospital, Cameroon, running from the 18th August 2021 to 28th February 2022. Logistic regression used to asses relationship between predictors and outcome.\r\nResults: Our 1254 participants had a mean age of 50.1(\u00b119.6) years, we had 24 (1.9%) being fully vaccinated, where 7 (29.2%) took heterologous vaccines. Also, 721 (57.5%) had the moderate\/severe form of the disease. Those fully vaccinated had lower odds of having severe disease (p=0.037). However, heterologous vaccination compared to homologous vaccination had no significant difference on morbidity (p=0.729). Among patients who died, none was fully vaccinated.\r\nConclusion: The protective effect of vaccination on morbidity was similar in those with heterologous vaccination as well as those who took\r\nKeywords: COVID-19 vaccine; heterologous vaccination; homologous vaccination.<\/jats:p>","DOI":"10.4314\/ahs.v24i4.11","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T14:30:58Z","timestamp":1741357858000},"page":"85-90","source":"Crossref","is-referenced-by-count":0,"title":["The effectiveness of COVID-19 Heterologous Vaccination: the experience from a Regional Hospital in Cameroon"],"prefix":"10.4314","volume":"24","author":[{"given":"Princewill","family":"Kum Unji","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Mambap Tatang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Angwafor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loveline","family":"Lum Niba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adji","family":"Minette Jaqueline Porro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis","family":"Nsame Nforniwe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Chiabi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2895","published-online":{"date-parts":[[2025,1,11]]},"container-title":["African Health Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/286055\/269506","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/286055\/269506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T14:32:11Z","timestamp":1741357931000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/view\/286055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,11]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,1,11]]}},"URL":"https:\/\/doi.org\/10.4314\/ahs.v24i4.11","relation":{},"ISSN":["1729-0503","1680-6905"],"issn-type":[{"value":"1729-0503","type":"electronic"},{"value":"1680-6905","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1,11]]}}}