{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T15:27:23Z","timestamp":1778772443798,"version":"3.51.4"},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Afr H. Sci."],"abstract":"<jats:p>Background: Antimicrobial susceptibility testing for post-surgical site infections is crucial amid rising cases and antibiotic resistance.Objective: This study aimed to evaluate demographic factors, the occurrence of surgical wound site infections, pathogens associated with these infections, and antimicrobial susceptibility of the isolated pathogens.Subjects and Methods: A cross-sectional study including 384 patients suffering from post-surgical site infections was conducted in tertiary care hospitals in Pakistan over six months.Results: The study participants\u2019 ages ranged from 7 to 74 years old, with a mean age (\u00b1SD) of 30.4 (\u00b19.5) years, and 44.8% of them were female. Among 384 study subjects, bacterial pathogens were isolated from 295 (76.80%). The frequency of gram-negative was 58.75%, whereas the frequency of gram-negative was 41.25%. Methicillin-resistant Staphylococcus aureus (MRSA), (19%), Staphylococcus aureus (Staph aureus) (18.0%), and Escherichia coli (E. coli) (18.0%) were the most common organisms isolated from wound infections. A significant association was present between occupation and culture sensitivity with a p-value of 0.01. Most of the culture-positive population had appendectomy site infection (92.90%). MRSA had the highest sensitivity to vancomycin (89.8%) and the highest resistance to gentamicin (85.7%). Staph. aureus was most sensitive to imipenem (80%) and most resistant to gentamicin (68.4%). E. coli was most sensitive to imipenem (100%) and most resistant to ceftazidime (90%).Conclusion: This study has provided a thorough description of the prevalence of gram-positive and gram-negative bacteria, as well as their relationships to wound type and demographic parameters.\r\nKeywords: Antibiotics; gram-positive; gram-negative; sensitive; resistant.<\/jats:p>","DOI":"10.4314\/ahs.v25i1.2","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:43:38Z","timestamp":1753875818000},"source":"Crossref","is-referenced-by-count":1,"title":["Antimicrobial susceptibility pattern of pathogens isolated from surgical wound infections in tertiary care hospitals of Pakistan"],"prefix":"10.4314","volume":"25","author":[{"given":"Rashid","family":"Iqbal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Palwasha","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zumaira","family":"Tahir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2895","published-online":{"date-parts":[[2025,5,9]]},"container-title":["African Health Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/294891\/277493","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/294891\/277493","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T14:06:33Z","timestamp":1762524393000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/view\/294891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,9]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,5,9]]}},"URL":"https:\/\/doi.org\/10.4314\/ahs.v25i1.2","relation":{},"ISSN":["1729-0503","1680-6905"],"issn-type":[{"value":"1729-0503","type":"electronic"},{"value":"1680-6905","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,9]]}}}