{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T14:09:06Z","timestamp":1764770946130,"version":"3.46.0"},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Afr H. Sci."],"abstract":"<jats:p>Background: Increase in antimicrobial resistance poses a global threat for treatment of Salmonellosis.\r\nObjectives: In this study, serovar distribution, antimicrobial susceptibility, resistance genes, and clonal diversity were characterized in clinical Salmonella isolates.\r\nMethods: In this study, serovar distribution of clinical Salmonella isolates was characterized by the Kauffman-White scheme. The antimicrobial susceptibility was determined by the broth microdilution method. Resistance genes and clonal diversity were investigated by PCR and PFGE.\r\nResults: The serovars were Salmonella enterica serovar Enteritidis (n=92), Salmonella enterica serovar Typhimurium (n=14), and others (n=25). Resistance to ciprofloxacin, ceftriaxone, trimethoprim-sulfamethoxazole, azithromycin, meropenem, and colistin were 13.3%, 2.2%, 5.2%, 3.0%, 0%, 29.6%, respectively. Two ESBL-positive isolates carried TEM-type \u03b2-lactamases. Carbapenemases, mcr-1 and mcr-2 could not be detected. Colistin-resistant S. Enteritidis isolates were grouped in 4 pulsotypes [A1 (n=12), A2 (n=2), A3 (n=13) and B (n=1)]. All except one (B) were found closely related.\r\nConclusions: A relative decrease in resistance to trimethoprim-sulfamethoxazole was detected with time. Trimethoprim-sulfamethoxazole and azithromycin can be good alternatives to the widely-used ciprofloxacin and third-generation cephalosporins. High resistance of colistin and ciprofloxacin may be due to the extensive use of antibiotics in poultry, which highlights the significance of one health concept.\r\nKeywords: Salmonella; colistin; trimethoprim-sulfamethoxazole; ESBL; ciprofloxacin; PFGE.<\/jats:p>","DOI":"10.4314\/ahs.v25i2.10","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T09:13:21Z","timestamp":1756804401000},"page":"70-78","source":"Crossref","is-referenced-by-count":0,"title":["Salmonella serovars in a tertiary hospital in Turkey, 2015-2017: molecular epidemiology, antimicrobial resistance and molecular characteristics of resistance mechanisms"],"prefix":"10.4314","volume":"25","author":[{"given":"Tugce","family":"Unalan-Altintop","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selay","family":"Demirci-Duarte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozgen","family":"Koseoglu-Eser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aycan","family":"Gundogdu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asl\u0131","family":"Cakar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Revasiye","family":"Gulesen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belk\u0131s","family":"Levent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belgin","family":"Altun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Banu","family":"Sancak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"G\u00fcr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2895","published-online":{"date-parts":[[2025,7,15]]},"container-title":["African Health Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/300589\/282617","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/download\/300589\/282617","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T13:45:07Z","timestamp":1764769507000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/ahs\/article\/view\/300589"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,15]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,7,15]]}},"URL":"https:\/\/doi.org\/10.4314\/ahs.v25i2.10","relation":{},"ISSN":["1729-0503","1680-6905"],"issn-type":[{"type":"electronic","value":"1729-0503"},{"type":"print","value":"1680-6905"}],"subject":[],"published":{"date-parts":[[2025,7,15]]}}}