{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T00:30:33Z","timestamp":1721867433161},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ethiop J Health Sci"],"abstract":"<jats:p>BACKGROUND: Colorectal cancer (CRC) is one of the most prevalent and incident cancers worldwide with an Increasing prevalence in a younger age in developing countries. The aim of the study was to determine the staging and imaging pattern of CRC at diagnosis.\r\nMETHODS: This is a descriptive cross-sectional study including all consecutive cases of CRC found in the departments of radiology and oncology during the study period from March 2016 - February 2017.\r\nRESULTS: A total of 132 CRC cases were studied with\u00a0M: F\u00a0= 2.4:1, mean age of\u00a0\u00a046yrs and\u00a0\u00a067.4%\u00a0\u00a0&lt;\/= 50yrs. Left-sided tumors were associated with rectal bleeding (p = 0.001) and bowel habit change\u00a0(p\u00a0=0.045) whereas right-side tumors were associated with weight loss ( p = 0.02) and abdominal pain ( p = 0.004).\u00a0\u00a084.5% of CRC presented at an advanced stage, and 32% had distant metastasis. Young age was associated with the advanced stage (P=0.006) whereas family history was associated with the lower stage (P=0.008). Distance metastasis was associated with Colonic lesions (P=0.003) and emergent presentation (P=0.008). Asymmetric wall thickening with luminal narrowing was significantly associated with left side tumor (95% vs 21.4%) whereas large mass with necrosis was significantly associated with right side tumor (50% vs 5%) (P= 0.004),\r\nCONCLUSION: CRC is presented at a younger age and at an advanced stage. The majority of CRCs were left-sided and rectal. Increasing the index of suspicion for CRC in patients with rectal bleeding and, bowel habit change is recommended.\u00a0<\/jats:p>","DOI":"10.4314\/ejhs.v33i1.11","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T09:30:16Z","timestamp":1721813416000},"source":"Crossref","is-referenced-by-count":0,"title":["High Magnitude Advanced Colorectal Cancer at Diagnosis in Ethiopian Patients: Imaging Pattern and Associated Factors"],"prefix":"10.4314","volume":"33","author":[{"family":"Assefa Getachew Kebede","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Tesfaye Kebede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Asfaw Atnafu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2895","published-online":{"date-parts":[[2023,1,1]]},"container-title":["Ethiopian Journal of Health Sciences"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/ejhs\/article\/download\/244593\/231345","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/ejhs\/article\/download\/244593\/231345","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T09:30:35Z","timestamp":1721813435000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/ejhs\/article\/view\/244593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,3,26]]}},"URL":"https:\/\/doi.org\/10.4314\/ejhs.v33i1.11","relation":{},"ISSN":["2413-7170","1029-1857"],"issn-type":[{"value":"2413-7170","type":"electronic"},{"value":"1029-1857","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1,1]]}}}