{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:48:27Z","timestamp":1777074507925,"version":"3.51.4"},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["gmj"],"abstract":"<jats:p>Objectives: This study aimed to examine possible associations between previously undiagnosed subclinical hypothyroidism and short-term outcomes and mortality in a sample of Iraqi patients undergoing primary percutaneous coro-nary intervention for ST-segment elevation myocardial infarction.Design: This is a prospective observational cohort study.Setting: The study was conducted in a single tertiary referral centre in Baghdad, Iraq.Participants: Thyroid-stimulating hormone and free T4 levels were measured in 257 patients hospitalised with ST-elevation myocardial infarction who underwent primary percutaneous coronary intervention between January 2020 and March 2022.Main outcome measures: Adverse cardiovascular and renal events during hospitalisation and 30-day mortality were observed.Results: Previously undiagnosed subclinical hypothyroidism was detected in 36\/257 (14%) ST-elevation myocardial infarction patients and observed more commonly in females than males. Patients with subclinical hypothyroidism had significantly worse short-term outcomes, including higher rates of suboptimal TIMI Flow (&lt; III) (p =0.014), left ventricular ejection fraction \u2264 40% (p=0.035), Killip class &gt;I (p=0.042), cardiogenic shock (p =0.016), cardiac arrest in the hospital (p= 0.01), and acute kidney injury (p= 0.044). Additionally, 30-day mortality was significantly higher in patients with subclinical hypothyroidism (p= 0.029).Conclusion: Subclinical hypothyroidism previously undiagnosed and untreated had a significant association with adverse short-term outcomes and higher short-term mortality within 30 days compared to euthyroid patients undergoing primary percutaneous coronary intervention. Routine thyroid function testing during these patients' hospitalisation may be warranted.<\/jats:p>","DOI":"10.4314\/gmj.v57i1.6","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T14:40:47Z","timestamp":1678977647000},"page":"37-42","source":"Crossref","is-referenced-by-count":6,"title":["Short-term outcomes among patients with subclinical hypothyroidism undergoing primary percutaneous coronary intervention"],"prefix":"10.4314","volume":"57","author":[{"given":"Abdulameer","family":"J. al-Gburi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saba","family":"R. al-Obaidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wasnaa","family":"H. Abdullah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2895","published-online":{"date-parts":[[2023,2,28]]},"container-title":["Ghana Medical Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/download\/243175\/230005","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/download\/243175\/230005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T14:41:06Z","timestamp":1678977666000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/view\/243175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,28]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,3,10]]}},"URL":"https:\/\/doi.org\/10.4314\/gmj.v57i1.6","relation":{},"ISSN":["0016-9560"],"issn-type":[{"value":"0016-9560","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2,28]]}}}