{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T20:45:44Z","timestamp":1788468344656,"version":"build-2803163510"},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["gmj"],"abstract":"<jats:p>Objective: We determined the incidence of blood culture-related sepsis, causative bacteria, and antibiotics sensitivity among newborn babies with suggestive signs of sepsis admitted at the Upper East Regional Hospital in Bolgatanga, Ghana.Design: Prospective cross-sectional studySetting: Newborn Care Unit of the Upper East Regional Hospital, BolgatangaParticipants: Neonates admitted to the Newborn Care Unit from August 2019 to August 2020 with signs of sepsisMain outcome measures: Organisms isolated from blood cultures and sensitivity of isolated organisms to antibiotics.Results: The study included two hundred and seventy-six (276) patients. Laboratory confirmed sepsis was 13.4% (37\/276). Early onset sepsis was 3.3% (9\/276), while late-onset sepsis was 10.1% (28\/276). The most common clinical signs associated with positive culture cases were temperature instability (35.5%), poor feeding (14.5%), neonatal jaundice (11.3%), vomiting (9.7%), and respiratory distress (8.1%). Staphylococcus aureus and Staphylococcus epidermidis were the most common bacterial isolates (46% and 32%, respectively). There was no relationship between independent variables and blood culture confirmed sepsis. Antibiotics to which isolates were most resistant included flucloxacillin 4\/4, penicillin 14\/15, ampicillin 16\/18, and tetracycline 23\/28. Bacterial isolates were most sensitive to amikacin 16\/16, levofloxacin 5\/5, erythromycin 8\/8, cefazolin 7\/8, and ciprofloxacin 18\/24.Conclusion: Late-onset sepsis is a common sepsis category, and the implicated microorganisms are resistant to commonly prescribed antibiotics.<\/jats:p>","DOI":"10.4314\/gmj.v57i2.8","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T07:39:59Z","timestamp":1686296399000},"page":"134-140","source":"Crossref","is-referenced-by-count":6,"title":["Incidence of blood culture-related sepsis in neonates and antibiotics sensitivity of implicated organisms in a secondary healthcare facility in Ghana"],"prefix":"10.4314","volume":"57","author":[{"given":"Francis","family":"K. Wuni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"W. Kukeba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwashie","family":"S. N. Dzotsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman","family":"Abu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Atobrah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasheed","family":"Ofosu-Poku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2895","published-online":{"date-parts":[[2023,6,1]]},"container-title":["Ghana Medical Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/download\/249087\/235545","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/download\/249087\/235545","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T07:40:05Z","timestamp":1686296405000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/view\/249087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,1]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,6,9]]}},"URL":"https:\/\/doi.org\/10.4314\/gmj.v57i2.8","relation":{},"ISSN":["0016-9560"],"issn-type":[{"value":"0016-9560","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6,1]]}}}