{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:31:55Z","timestamp":1790260315062,"version":"4.1.0"},"reference-count":0,"publisher":"African Journals Online (AJOL)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["gmj"],"abstract":"<jats:p>Objective: To determine the prevalence of anaemia, clinical features, hospitalisation outcomes, and associated factors among paediatric patients with severe malaria-related anaemia admitted to a tertiary hospital in northwestern Nigeria.Design: This was a retrospective study of children with confirmed severe malaria-related anaemia admitted between 2019 and 2022.Participants: Paediatric patients aged three months to 14 years with confirmed severe malaria-related anaemiaMain outcomes measures: Hospitalization outcomes and associated factors among paediatric study patients.Results: There were 278 malaria-related anaemia cases with a prevalence of 29.3% (278\/948) among malaria cases and 3.4% (278\/8,295) among all paediatric admissions. Of 278 patients with malaria-related anaemia, 110 (39.6%) had severe anaemia. The prevalence of severe anaemia was 11.6% (110\/948) and 1.3% (110\/8,295) from malaria cases and paediatric admissions, respectively. Clinical features were comparable across the levels of anaemia except for the loss of consciousness (p = 0.038). Severe anaemia was more common among under-fives (76\/159, 47.8%), p=003, and males (p = 0.013). The crude mortality rate was 6.5% (18\/278) and comparable [6.4%, (7\/110)] with severe anaemia (p = 0.924). Factors that were associated with hospitalisation deaths included unconsciousness [adjusted odds ratio (AOR) 5.8, 95% confidence interval (CI) 1.800-18.441], hypoxemia AOR [7.3, 95% CI, 1.749- 30.473] and first 24 hours of admission, AOR [18.4, 95% CI 3.430-98.705].Conclusion: In childhood, severe malaria anaemia remains a greater burden among under five and is associated with high mortality. Unconsciousness and hypoxemia at presentation and the first 24 hours of admission were associated with increased odds of death.<\/jats:p>","DOI":"10.4314\/gmj.v58i4.3","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T14:50:11Z","timestamp":1737643811000},"page":"262-268","source":"Crossref","is-referenced-by-count":3,"title":["Outcomes and factors associated with severe malaria-related anaemia in paediatric patients in northern Nigeria"],"prefix":"10.4314","volume":"58","author":[{"given":"Olayinka","family":"R. Ibrahim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amudalat","family":"Issa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"A. Alao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bello","family":"M. Suleiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2895","published-online":{"date-parts":[[2025,1,10]]},"container-title":["Ghana Medical Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/download\/285755\/269224","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/download\/285755\/269224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T14:50:20Z","timestamp":1737643820000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/gmj\/article\/view\/285755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,10]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,1,10]]}},"URL":"https:\/\/doi.org\/10.4314\/gmj.v58i4.3","relation":{},"ISSN":["0016-9560"],"issn-type":[{"value":"0016-9560","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1,10]]}}}