{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T12:21:04Z","timestamp":1764937264526},"reference-count":0,"publisher":"ScopeMed","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Vet J."],"abstract":"<jats:p>Background: Canine lymphoma is one of the most frequently occurring malignant neoplasms in dogs. Anthracycline-based chemotherapy for the treatment of canine lymphoma is very effective; however, there is not enough evidence for the development of cardiac toxicity using several anthracyclines as chemotherapeutic agents.&#x0D;\nCase Description: An 8-year-old, castrated, mixed-breed dog was diagnosed with multicentric lymphoma and received multi-agent chemotherapy. Complete remission was achieved, but the patient had a relapse of lymphoma. After third-line chemotherapy with epirubicin, the patient was diagnosed with dilated cardiomyopathy. The total cumulative doses of doxorubicin, mitoxantrone, and epirubicin were 125, 8, and 125 mg\/m2, respectively. Although the patient was treated with cardiac drugs and clinically stabilized, the patient had a relapse of lymphoma and died shortly after the diagnosis of cardiomyopathy.&#x0D;\nConclusion: The patient was suspected to have anthracycline-induced cardiomyopathy. Further studies are required to establish prevention and management strategies for dogs receiving potentially cardiotoxic therapies, such as anthracyclines.<\/jats:p>","DOI":"10.4314\/ovj.v11i1.2","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T08:00:13Z","timestamp":1616572813000},"page":"6-10","source":"Crossref","is-referenced-by-count":1,"title":["Cardiomyopathy in a dog with multicentric lymphoma following treatment with several anthracyclines"],"prefix":"10.5455","volume":"11","author":[{"given":"Michihito","family":"Tagawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genya","family":"Shimbo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Uemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kotaro","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3407","published-online":{"date-parts":[[2021,3,19]]},"container-title":["Open Veterinary Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/ovj\/article\/download\/204847\/193165","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/ovj\/article\/download\/204847\/193165","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T22:21:16Z","timestamp":1616710876000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/ovj\/article\/view\/204847"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,19]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,3,21]]}},"URL":"https:\/\/doi.org\/10.4314\/ovj.v11i1.2","relation":{},"ISSN":["2218-6050","2226-4485"],"issn-type":[{"value":"2218-6050","type":"electronic"},{"value":"2226-4485","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3,19]]}}}