{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T05:36:16Z","timestamp":1792215376663,"version":"4.4.0"},"reference-count":0,"publisher":"ScopeMed","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Vet J."],"abstract":"<jats:p>In human medicine, in the past, open-heart techniques for low-bodyweight children and newborn babies with congenital heart disease were more difficult than high-bodyweight adults. In toy- and small-breed dogs with mitral regurgitation (MR), an acquired heart disease, these techniques are more difficult to perform than for congenital heart diseases in young medium-sized or large dogs because of old age and low body weight. Therefore, improved open-heart techniques and mitral valve surgery for severe MR in older toy- and small-breed dogs are essential. Through our surface-cooling hypothermia (sHT) studies, we designed a new, improved open-heart method, namely, \u201cthe low-flow cardiopulmonary bypass (CPB) combined with deep sHT in toy- and small-breed dogs (Japan method)\u201d; sHT was later replaced by blood-cooling hypothermia (bHT). At the same time, we devised a new, improved mitral valve plasty (MVP) applicable to severe MR, instead of mitral valve replacement, in toy- and small-breed dogs. This MVP technique was combined with artificial chordal reconstruction, semi-circular suture annuloplasty (AP), and direct scallop-suture valvuloplasty. These MVP techniques are simple, durable, and lead to good long-term quality of life in toy- and small-breed dogs. This review highlights the benefits of our improved CPB and MVP techniques (Japan method) for severe MR in toy-and small-breed dogs, which have led to a high success rate for MVP in severe clinical MR cases in Japan. It may further contribute to the development of more robust techniques for MR in toy- and small-breed dogs. This also represents the first comprehensive review of the history of open-heart surgery, CPB techniques, and MVP methods for MR in toy- and small-breed dogs.<\/jats:p>","DOI":"10.4314\/ovj.v11i1.4","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T08:00:13Z","timestamp":1616572813000},"page":"14-26","source":"Crossref","is-referenced-by-count":28,"title":["Open-heart techniques and mitral valve plasty for mitral regurgitation in toy- and small-breed dogs: A review"],"prefix":"10.5455","volume":"11","author":[{"given":"Isamu","family":"Kanemoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kippei","family":"Mihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3407","published-online":{"date-parts":[[2021,3,19]]},"container-title":["Open Veterinary Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.ajol.info\/index.php\/ovj\/article\/download\/204849\/193167","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajol.info\/index.php\/ovj\/article\/download\/204849\/193167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T22:21:14Z","timestamp":1616710874000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajol.info\/index.php\/ovj\/article\/view\/204849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,19]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,3,21]]}},"URL":"https:\/\/doi.org\/10.4314\/ovj.v11i1.4","relation":{},"ISSN":["2218-6050","2226-4485"],"issn-type":[{"value":"2218-6050","type":"electronic"},{"value":"2226-4485","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3,19]]}}}