{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T03:02:09Z","timestamp":1784862129169,"version":"3.55.0"},"reference-count":28,"publisher":"Baishideng Publishing Group Inc.","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Radiol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n                  <jats:p>Selective internal radiation therapy (SIRT) has been widely used in the treatment of hepatocellular carcinoma (HCC). However, marked intrahepatic shunt (IHS) secondary to arterio-portal shunt (APS) often precludes safe SIRT administration.<\/jats:p>\n                  <jats:p>AIM<\/jats:p>\n                  <jats:p>To evaluate the efficacy and safety of portal vein embolization (PVE) in reducing IHS and enabling SIRT therapy in HCC patients with APS.<\/jats:p>\n                  <jats:p>METHODS<\/jats:p>\n                  <jats:p>This retrospective study enrolled seven HCC patients with APS confirmed by hepatic angiography during mapping. PVE was performed to close the APS outlet and single photon emission computed tomography\/computed tomography was performed to determine the distribution of (99m) technetium-labeled macroaggregated albumin. These patients meeting the criteria for SIRT subsequently underwent Yttrium-90 (Y-90) resin microspheres administration. Changes in liver function and complications were monitored during the 6-month follow-up period.<\/jats:p>\n                  <jats:p>RESULTS<\/jats:p>\n                  <jats:p>Complete APS occlusion was achieved in six patients (n  = 6, 6\/7). The hepatopulmonary shunt rate was below 20% (4.65%-16.95%) in five of six patients with APS occluded, and Y-90-SIRT was subsequently administered in these patients. No severe procedural complications occurred.<\/jats:p>\n                  <jats:p>CONCLUSION<\/jats:p>\n                  <jats:p>PVE is a safe and effective strategy to reduce IHS in HCC patients with APS, thereby improving eligibility for SIRT.<\/jats:p>","DOI":"10.4329\/wjr.121348","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T09:04:46Z","timestamp":1782205486000},"source":"Crossref","is-referenced-by-count":0,"title":["Portal vein embolization for arterio-portal shunt closure in hepatocellular carcinoma to facilitate selective internal radiation therapy"],"prefix":"10.4329","volume":"18","author":[{"given":"Xue","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Yan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Yuan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Qun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Jia","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye-Fa","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nai-Jian","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang-Dong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acr.2020.10.001"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12071914"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_200939"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i29.5282"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15245749"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12972"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2023.07.007"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.08.029"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-016-0324-7"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1994.436"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.169.2.3174978"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-018-0899-3"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviscsurg.2020.01.010"},{"key":"B14","unstructured":"Maspes F, Gandini R, Pocek M, Montanaro M, Guazzaroni M, Simonetti G. [Treatment of intrahepatic arteriovenous fistula after biopsy. Results in 5 chemoembolization candidates with hepatocarcinoma]. Radiol Med 1997; 418-424"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1159\/000507262"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.14131969"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-016-1530-z"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.4103\/jcrt.JCRT_286_17"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-009-1349-y"},{"key":"B20","unstructured":"Chan WS, Poon WL, Cho DH, Chiu SS, Luk SH. Transcatheter embolisation of intrahepatic arteriovenous shunts in patients with hepatocellular carcinoma. Hong Kong Med J 2010; 48-55"},{"key":"B21","unstructured":"Sugano S, Miyoshi K, Suzuki T, Kawafune T, Kubota M. Intrahepatic arteriovenous shunting due to hepatocellular carcinoma and cirrhosis, and its change by transcatheter arterial embolization. Am J Gastroenterol 1994; 184-188"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-022-03283-z"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.2147\/JHC.S456460"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v15.i12.2926"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-011-1812-2"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i7.2229"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2012.04.007"},{"key":"B28","unstructured":"Izaki K, Sugimoto K, Sugimura K, Hirota S. Transcatheter arterial embolization for advanced tumor thrombus with marked arterioportal or arteriovenous shunt complicating hepatocellular carcinoma. Radiat Med 2004; 155-162"}],"container-title":["World Journal of Radiology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1949-8470\/full\/v18\/i7\/121348.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1949-8470\/full\/v18\/i7\/121348.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T02:42:14Z","timestamp":1784860934000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1949-8470\/full\/v18\/i7\/121348.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,28]]},"references-count":28,"journal-issue":{"issue":"7"},"alternative-id":["121348"],"URL":"https:\/\/doi.org\/10.4329\/wjr.121348","relation":{},"ISSN":["1949-8470"],"issn-type":[{"value":"1949-8470","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,28]]}}}