{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:40:53Z","timestamp":1793396453836,"version":"4.5.0"},"reference-count":112,"publisher":"Baishideng Publishing Group Inc.","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJC"],"published-print":{"date-parts":[[2021,12,26]]},"DOI":"10.4330\/wjc.v13.i12.654","type":"journal-article","created":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T23:55:33Z","timestamp":1640217333000},"page":"654-675","source":"Crossref","is-referenced-by-count":73,"title":["Chagas heart disease: An overview of diagnosis, manifestations, treatment, and care"],"prefix":"10.4330","volume":"13","author":[{"given":"Roberto M","family":"Saraiva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro Felippe F","family":"Mediano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda SNS","family":"Mendes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilberto Marcelo","family":"Sperandio da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique H","family":"Veloso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Henrique C","family":"Sangenis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Simpl\u00edcio da","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Mazzoli-Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9a S","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo T","family":"Holanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro M","family":"Hasslocher-Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000599"},{"key":"B2","unstructured":"World Health Organization.   Chagas Disease (American trypanosomiasis). 2021. Available from: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/chagas-disease-(american-trypanosomiasis)"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/789758"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002300"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz087"},{"key":"B6","doi-asserted-by":"crossref","unstructured":"Basile L, Jansa JM, Carlier Y, Salamanca DD, Angheben A, Bartoloni A, Seixas J, Van Gool T, Canavate C, Flores-Chavez M, Jackson Y, Chiodini PL, Albajar-Vinas P; Working Group on Chagas Disease. Chagas disease in European countries: the challenge of a surveillance system. Euro Surveill 2011; 16","DOI":"10.2807\/ese.16.37.19968-en"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2020.25.8.1900393"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1590\/0074-02760170298"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0505-2016"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1111\/pim.12107"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2019.165642"},{"key":"B12","doi-asserted-by":"crossref","unstructured":"Andrade JP, Marin-Neto JA, Paola AA, Vilas-Boas F, Oliveira GM, Bacal F, Bocchi EA, Almeida DR, Fragata Filho AA, Moreira Mda C, Xavier SS, Oliveira Junior WA, Dias JC; Sociedade Brasileira de Cardiologia. I Diretriz Latino Americana para o Diagn\u00f3stico e Tratamento da Cardiopatia Chag\u00e1sica. [I Latin American guidelines for the diagnosis and treatment of Chagas cardiomyopathy]. Arq Bras Cardiol 2011; 97: 1-48","DOI":"10.1590\/S0066-782X2011000600002"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jex154"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa053241"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.117.004361"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006207"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2020.100694"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-10-200605160-00006"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1507574"},{"key":"B20","doi-asserted-by":"crossref","unstructured":"Chagas C, Villela E. Cardiac form of American Trypanosomiasis. Mem Inst Oswaldo Cruz 1922; 14: 3-54","DOI":"10.1590\/S0074-02761922000100001"},{"key":"B21","unstructured":"Dias E, Laranja FS, Nobrega G. Clinical and therapeutic Chagas disease. Medicina (Mex) 1948; 28: 224-236"},{"key":"B22","unstructured":"Laranja FS, Dias E, Nobrega G. [The electrocardiogram in chronic cardiopathy of Chagas' disease]. Bras Med 1948; 62: 51-53"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.14.6.1035"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.018960"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.123612"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2009.11.008"},{"key":"B27","unstructured":"Kuschnir E, Sgammini H, Castro R, Evequoz C, Ledesma R, Brunetto J. [Evaluation of cardiac function by radioisotopic angiography, in patients with chronic Chagas cardiopathy]. Arq Bras Cardiol 1985; 45: 249-256"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(82)90232-0"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.03.372"},{"key":"B30","unstructured":"Minist\u00e9rio da Sa\u00fade (BR).   [Protocolo Cl\u00ednico e Diretrizes Terap\u00eauticas da doen\u00e7a de Chagas, no \u00e2mbito do Sistema \u00danico de Sa\u00fade - SUS. 2018]. Available from: http:\/\/conitec.gov.br\/images\/Protocolos\/Relatorio_PCDT_Doenca_de_Chagas.pdf"},{"key":"B31","unstructured":"Panamerican Health Organization.   Guidelines for the diagnosis and treatment of Chagas disease. 2018. Available from:  https:\/\/iris.paho.org\/bitstream\/handle\/10665.2\/49653\/9789275120439_eng.pdf?sequence=6&isAllowed=y"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008399"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.gheart.2015.07.003"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.21470\/1678-9741-2017-0134"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.01.035"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.05.011"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1111\/tid.13549"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.014176"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1590\/s0066-782x2008001700004"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.06.012"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.08.018"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1590\/s0074-02762009000900022"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/trt050"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.026856"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq106"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-2167(03)00078-7"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1590\/s0100-879x2006000400008"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60061-X"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1590\/s0037-86822007000500006"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000163104.92943.50"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1159\/000320248"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.gheart.2015.07.006"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.1998.tb00607.x"},{"key":"B54","doi-asserted-by":"crossref","unstructured":"Benchimol Barbosa PR. Noninvasive prognostic markers for cardiac death and ventricular arrhythmia in long-term follow-up of subjects with chronic Chagas' disease. Braz J Med Biol Res 2007; 40: 167-178","DOI":"10.1590\/S0100-879X2006005000061"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2003.05.003"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2002.123575"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2011.08.007"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12426"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2016.03.007"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0221028"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2020.06.003"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.210047"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.09.035"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.08.2195"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2001.111406"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12368"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2012.109"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006742"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp100"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.592"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut422"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut011"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa071098"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(90)90302-h"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1999.tb00311.x"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.1996.tb00559.x"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.04.030"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2014.09.003"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12845"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euv185"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90085-1"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2021.02.025"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1177\/1076029610375814"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1590\/s0004-282x1994000200008"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1159\/000182819"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000177866.13451.e4"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2016.02.015"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000024"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2020.105169"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000435566.30728.be"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000148720.81701.B6"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1007\/s40256-020-00458-2"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.5334\/gh.484"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1016\/j.rec.2016.04.054"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002176"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009077.pub3"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.12240"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.12355"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13279"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcnurse.2009.05.005"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2018.12.008"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.114.100750"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.14152"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0443-2019"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0000000000000045"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1177\/2047487320913379"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2020.1800837"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1177\/2047487313498832"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.70"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00943.2011"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1177\/2047487318798917"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfr017"}],"container-title":["World Journal of Cardiology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1949-8462\/full\/v13\/i12\/654.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T23:55:44Z","timestamp":1640217344000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1949-8462\/full\/v13\/i12\/654.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,26]]},"references-count":112,"journal-issue":{"issue":"12"},"URL":"https:\/\/doi.org\/10.4330\/wjc.v13.i12.654","relation":{},"ISSN":["1949-8462"],"issn-type":[{"value":"1949-8462","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12,26]]}}}