{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T21:56:37Z","timestamp":1778018197601,"version":"3.51.4"},"reference-count":24,"publisher":"Baishideng Publishing Group Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Cardiol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Significant gaps in guideline-directed medical therapy (GDMT) for heart failure (HF) stem from shortages of cardiologists and advanced HF providers, as well as a lack of optimal HF management knowledge among hospitalists. This study compared the impact of optimal medical therapy in HF (OMT-HF) certification on GDMT implementation and patient outcomes between an intervention group (IG) of hospitalists and a standard-of-care comparison group (SOC-CG).<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To evaluate if OMT-HF has a difference in GDMT and patients in outcomes between IG and SOC-CG.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>This study was implemented from November 2022 to May 2023. Hospitalized cardiology patients with HF and left ventricular ejection fraction \u2264 40% were randomized to IG or SOC-CG. Exclusion criteria included patients in cardiogenic shock, unable to consent, or at high risk. Follow-up was at 30 days post-discharge. Differences between groups were analyzed using Fisher\u2019s exact test for categorical variables and Wilcoxon rank-sum or unpaired t -test for continuous variables. Changes in Minnesota Living with Heart Failure Questionnaire (MLWHFQ) scores were evaluated using a paired t -test.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>IG patients had lower readmission rates [(9 (42.85%) vs  11 (17.46%), P  = 0.03] and a decreased trend in mortality 30-day post discharge. IG patients also showed greater mean improvements in total (-27.03 \u00b1 24.59 vs  -5.85 \u00b1 23.52, P  &lt; 0.001), physical (-13.8 \u00b1 12.3 vs  -2.71 \u00b1 11.16, P  &lt; 0.001) and emotional (-4.76 \u00b1 8.10 vs  -1.42 \u00b1 5.98) dimensions on the MLWHFQ compared to SOC-CG, however, change in emotional dimension did not reach statistical significance.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Hospitalist OMT-HF certification may lead to better 30-day outcomes in hospitalized HF patients including quality of life, mortality and readmission rates. Larger prospective studies are warranted to validate these findings.<\/jats:p>","DOI":"10.4330\/wjc.v17.i6.107102","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T02:11:46Z","timestamp":1750385506000},"source":"Crossref","is-referenced-by-count":2,"title":["Impact of optimal medical therapy in heart failure certification for hospitalists on guideline-directed medical therapy utilization"],"prefix":"10.4330","volume":"17","author":[{"given":"Farhan","family":"Ishaq","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duc T","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward A","family":"Graviss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebun","family":"Ebunlomo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arvind","family":"Bhimaraj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Fida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,6,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.7472"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2023.05.040"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.121.008335"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1177\/23779608231209220"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.04.070"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2018.01.006"},{"key":"B7","unstructured":"Fonarow GC; ADHERE Scientific Advisory Committee. The Acute Decompensated Heart Failure National Registry (ADHERE): opportunities to improve care of patients hospitalized with acute decompensated heart failure. Rev Cardiovasc Med 2003; S21-S30"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2019.00158"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.11.033"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2018"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-016-0425-7"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd10080315"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/s0735-1097(97)00176-9"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1002\/clc.23845"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2017.03.012"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2019.89702"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)02076-1"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines12050951"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2024.09.013"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.37765\/ajmc.2024.89533"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2888"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1097\/NCM.0000000000000600"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2022.01.028"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1097\/HRP.0000000000000162"}],"container-title":["World Journal of Cardiology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1949-8462\/full\/v17\/i6\/107102.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1949-8462\/full\/v17\/i6\/107102.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T02:12:03Z","timestamp":1750385523000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1949-8462\/full\/v17\/i6\/107102.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,26]]},"references-count":24,"journal-issue":{"issue":"6"},"alternative-id":["107102"],"URL":"https:\/\/doi.org\/10.4330\/wjc.v17.i6.107102","relation":{},"ISSN":["1949-8462"],"issn-type":[{"value":"1949-8462","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,26]]}}}