{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T03:13:03Z","timestamp":1758078783069,"version":"3.44.0"},"reference-count":25,"publisher":"Baishideng Publishing Group Inc.","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Cardiol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Peripheral endovascular intervention (PEVI) is performed using radiation. Radiation has deleterious health consequences for patients and operators.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To investigate the gender radiation disparities and procedural outcomes in PEVI.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>A prospective observational study was performed in 186 consecutive patients (65 \u00b1 12 years) at an academic medical center from January 2019 to April 2020 (mean follow-up of 3.9 \u00b1 3.6 months) comparing the gender radiation disparity and outcomes of PEVI (n  = 147 underwent intervention, 79.0%). Groups were divided into women (n  = 99, 53.2%) and men (n  = 87, 48.4%). Primary endpoints included air kerma, dose area product (DAP), fluoroscopy time, and contrast use. Secondary endpoints included all-cause mortality, acute myocardial infarction, acute kidney injury, stroke, repeat revascularization, major adverse limb event, and the composite of complications.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>Men showed increased DAP compared with women (15221.2 \u00b1 25858.5 \u00b5Gy \u00d7 m2 vs  9251.7 \u00b1 9555.3 \u00b5Gy \u00d7 m2, P  = 0.047), but no significant difference in air kerma or any other primary endpoints. In the secondary endpoints, no significant difference was found between gender.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Men had increased DAP indicating more radiation absorption in the exposed area. Gender outcomes showed no difference in complications. Thus, PEVI can be safely performed in men or women.<\/jats:p>","DOI":"10.4330\/wjc.v17.i9.110220","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:46:56Z","timestamp":1758012416000},"source":"Crossref","is-referenced-by-count":0,"title":["Gender-based radiation exposure and clinical outcomes in peripheral endovascular intervention for limb ischemia: A prospective study"],"prefix":"10.4330","volume":"17","author":[{"given":"Subrata","family":"Kar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clifton","family":"Espinoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,9,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61249-0"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001153"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.115.003273"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27173"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmp.2017.10.007"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27114"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.12.060"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25927"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.08.009"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.08.051"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2015.11.019"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2542082312"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2014.03.236"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.03.036"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.07.114"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.11.001"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1148\/rg.285075748"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.06.016"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.5830\/CVJA-2022-046"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.11.005"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7120-9-35"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.010849"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.022043"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.11.057"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.25270\/jic\/18.00332"}],"container-title":["World Journal of Cardiology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1949-8462\/full\/v17\/i9\/110220.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1949-8462\/full\/v17\/i9\/110220.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:47:07Z","timestamp":1758012427000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1949-8462\/full\/v17\/i9\/110220.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,26]]},"references-count":25,"journal-issue":{"issue":"9"},"alternative-id":["110220"],"URL":"https:\/\/doi.org\/10.4330\/wjc.v17.i9.110220","relation":{},"ISSN":["1949-8462"],"issn-type":[{"value":"1949-8462","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9,26]]}}}