{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:19:38Z","timestamp":1773285578544,"version":"3.50.1"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"0708","license":[{"start":{"date-parts":[[2011,2,14]],"date-time":"2011-02-14T00:00:00Z","timestamp":1297641600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>BACKGROUND: Perinatal asphyxial  encephalopathy occurs in 1\u2013 per 1000 live births and is associated with high  mortality and morbidity. Therapeutic hypothermia increases intact survival and  improves neurodevelopmental outcome in survivors.\n        AIMS: To evaluate (i) the  opinion and practice of therapeutic hypothermia as a therapy for moderate to  severe perinatal asphyxial  encephalopathy amongst Swiss neonatologists and paediatric intensive care  specialists, (ii) the current clinical management of infants with perinatal asphyxial  encephalopathy and (iii) the need for a national perinatal  asphyxia and therapeutic hypothermia registry.\n        METHODS: Two web-based questionnaires were sent to 18  senior staff physicians within the Swiss Neonatal Network.\n        RESULTS: Therapeutic hypothermia was considered  effective by all responders, however only 11 of 18 units provided therapeutic  hypothermia. Cooling was initiated during transfer and performed passively in  82% of centres with a target rectal temperature of 33\u201334 \u00b0C. Most units  ventilated infants with perinatal asphyxial  encephalopathy if clinically indicated and 73% of responders gave analgesia  routinely to cooled infants. Neuromonitoring included  continuous amplitude integrated EEG (aEEG) and EEG. Neuroimaging included cranial ultrasound (cUS), magnetic resonance imaging (MRI) and computed  tomography (CT). Sixty-seven percent of units treating infants with perinatal asphyxial  encephalopathy performed MRI routinely. All heads of departments questioned  indicated that a \u201cSwiss National Asphyxia and Cooling Registry\u201d is needed.\n        CONCLUSIONS: In Switzerland, access to therapeutic  hypothermia is widespread and Swiss neonatologists believe that therapeutic  hypothermia for perinatal asphyxia is effective. National  cooling protocols are needed for the management of infants with perinatal asphyxial  encephalopathy in order to ensure safe cooling, appropriate monitoring, imaging  and follow-up assessment. A national registry is needed to collect data on  diagnosis, treatment, adverse events and outcome.<\/jats:p>","DOI":"10.4414\/smw.2011.13145","type":"journal-article","created":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T03:48:08Z","timestamp":1319687288000},"page":"w13145","source":"Crossref","is-referenced-by-count":9,"title":["Hypothermia  for perinatal asphyxial  encephalopathy"],"prefix":"10.57187","volume":"141","author":[{"given":"CF","family":"Hagmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Brotschi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Bernet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Latal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TM","family":"Berger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NJ","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"36756","published-online":{"date-parts":[[2011,2,14]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1255\/1394","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1255\/1395","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1255\/1394","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:44:53Z","timestamp":1755225893000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,14]]},"references-count":0,"journal-issue":{"issue":"0708","published-online":{"date-parts":[[2011,2,14]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2011.13145","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,14]]}}}