{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T21:39:46Z","timestamp":1774042786219,"version":"3.50.1"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"1516","license":[{"start":{"date-parts":[[2011,4,11]],"date-time":"2011-04-11T00:00:00Z","timestamp":1302480000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>BACKGROUND: The burden of ischemic heart  disease (IHD) in developing countries is on the rise, due to urbanisation,  industrialisation and the low availability of evidence based therapies and  interventions.\n        AIMS AND OBJECTIVES:Data was collected on consecutive  patients admitted with acute coronary syndrome (ACS), from 1st\u00a0January to 31st  December 2008, to a tertiary care centre in eastern Nepal. Final diagnosis, risk  factors, educational status,\u00a0time delays, treatment and in-hospital  outcomes were evaluated.\n        RESULTS:A total of153 patients  with ACS were admitted in 2008: 58 with ST elevation myocardial infarction  (STEMI) (38%), 28 with non-ST elevation myocardial infarction (NSTEMI) (18%)  and 67 with unstable angina (UA) (44%). 40% of patients with STEMI presented  within 12 hours of symptom onset. Most patients presented late and 33% of them  presented after 2 days or more. Over half the patients were not literate. Due  to the unavailability of percutaneous coronary intervention (PCI) at the  centre, thrombolysis with Streptokinase was considered for patients presenting  with STEMI up to 24 hours after symptom onset. However, due to financial  constraints, only 53% of patients in this broadened time window actually  received thrombolytic treatment. The in-hospital mortality was 14% for all  patients with ACS, and 17% for the patients with STEMI.\n        CONCLUSIONS:Only a small proportion of patients with ACS in Eastern   Nepal are admitted to hospital, and those who are often arrive  late, or cannot afford optimal medical management.  Awareness, better referral and transport  facilities, financial support for the needy, and the availability of on-site  coronary angiography and angioplasty for selected patients should contribute to  treat more ACS patients and improve their prognosis.<\/jats:p>","DOI":"10.4414\/smw.2011.13174","type":"journal-article","created":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T03:48:08Z","timestamp":1319687288000},"page":"w13174","source":"Crossref","is-referenced-by-count":4,"title":["Presentation  and outcomes of patients with acute coronary syndromes in eastern Nepal"],"prefix":"10.57187","volume":"141","author":[{"given":"NR","family":"Shreshta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Basnet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Bhandari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Acharia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Karki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"36756","published-online":{"date-parts":[[2011,4,11]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1275\/1434","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1275\/1435","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1275\/1434","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:50:12Z","timestamp":1755226212000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,11]]},"references-count":0,"journal-issue":{"issue":"1516","published-online":{"date-parts":[[2011,4,11]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2011.13174","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,11]]}}}