{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T16:52:09Z","timestamp":1775321529280,"version":"3.50.1"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"2526","license":[{"start":{"date-parts":[[2011,6,20]],"date-time":"2011-06-20T00:00:00Z","timestamp":1308528000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>OBJECTIVES: To determine the prevalence of primary  nocturnal enuresis in children, to define the possible role of sleep-disordered  breathing (SDB) related to adenotonsillar hypertrophy in  enuresis, to explore the role of brain natriuretic peptide (BNP) levels in measuring the  severity of SDB in enuretic children, and to evaluate the response to surgical  interventions (adenotonsillectomy) in indicated enuretic patients.\n        METHODS: Parental surveys of 5\u201310 year-old children were  reviewed for SDB and enuresis. Children with SDB were clinically and  radiologically examined. Plasma BNP levels were determined in 33 children with  SDB and enuresis and in 30 otherwise healthy children of whom 15 had enuresis.\n        RESULTS: A total of 15.3% of the studied children had  primary nocturnal enuresis, and 47 children with enuresis (30.7%) had SDB. There was a downward trend of enuresis and SDB as age increased.  There appeared to be an association between the frequency of enuresis, snoring and adenotonsillar  enlargement. Plasma BNP  concentrations were significantly higher among enuretic children. All\u00a0enuretic  children with SDB underwent surgical intervention (33 patients), and an improvement  was observed in 29 children (87.8%). Among them, 15 were cured completely,  and 12 made a significant improvement in the initial 3 months, but two made  just a partial improvement over one year, and four did not show any improvement over one year follow up. All enuretic children with SDB who underwent surgery  exhibited a significant reduction in daytime enuresis.\n        CONCLUSIONS: The data suggests an association between nocturnal enuresis and  adenotonsillar related SDB in children. Enuresis may  add to the indications for surgical intervention in this group. Increased BNP levels may account for  the increased prevalence of enuresis in context of SDB.<\/jats:p>","DOI":"10.4414\/smw.2011.13216","type":"journal-article","created":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T03:48:08Z","timestamp":1319687288000},"page":"w13216","source":"Crossref","is-referenced-by-count":10,"title":["Impact  of sleep-disordered breathing and its treatment on\u00a0children with primary nocturnal  enuresis"],"prefix":"10.57187","volume":"141","author":[{"given":"WF","family":"Ezzat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SA","family":"Fawaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SM","family":"Farid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"36756","published-online":{"date-parts":[[2011,6,20]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1306\/1496","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1306\/1497","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1306\/1496","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:59:19Z","timestamp":1755226759000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,20]]},"references-count":0,"journal-issue":{"issue":"2526","published-online":{"date-parts":[[2011,6,20]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2011.13216","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,20]]}}}