{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T09:18:02Z","timestamp":1781774282558,"version":"3.54.5"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"2728","license":[{"start":{"date-parts":[[2011,7,4]],"date-time":"2011-07-04T00:00:00Z","timestamp":1309737600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>PRINCIPLES: Whole body  vibration (WBV) is an increasingly popular modality of muscle training, especially  in sedentary subjects. We hypothesised that the vigorous muscle contractions  elicited by WBV can cause muscle damage expressed as an elevation in muscle enzymes.\n        METHODS: Twenty inactive  subjects, ten male and ten female, aged 22.7 \u00b1 2.6, BMI 22.4 \u00b1 2.1 were included  based on the absence of regular physical activity as defined by international  guidelines, and no history of recent trauma, musculoskeletal pathology,  implanted prosthetics, cardiovascular disease or drug intake. The intervention consisted of one bout of high intensity WBV corresponding to a  typical training session, involving all the major muscle groups. Plasma levels of muscle enzymes prior  to and at 24, 48 and 96 hours post exercise (creatine kinase \u2013 CK, MB  fraction, troponin I, aminotransferases and lactate dehydrogenase) were  measured. In addition, blood lactate was assayed immediately after exercise.  Delayed onset muscle soreness (DOMS) was evaluated using a visual analogical  scale.\n        RESULTS: Five participants (25%) showed a  significant increase in post exercise CK levels (&gt; double of baseline).  Maximal value was 3520 U\/l. No change was observed in CK-MB or troponin I.  Lactate increased to 10.0 \u00b1 2.4 in men and 6.9 \u00b1 2.4 in women. All participants  had some degrees of DOMS, without correlation to enzymatic changes.\n        DISCUSSION: WBV can provoke  high CK elevation in healthy, medication-free inactive subjects. Such an elevation  is transient and harmless, but could be wrongly attributed to drug induced  myopathy, as in patients treated with statins. Practitioners should bear this  in mind before discontinuing a potential life saving drug.<\/jats:p>","DOI":"10.4414\/smw.2011.13222","type":"journal-article","created":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T03:48:08Z","timestamp":1319687288000},"page":"w13222","source":"Crossref","is-referenced-by-count":13,"title":["Whole body  vibration training elevates creatine kinase levels in sedentary subjects"],"prefix":"10.57187","volume":"141","author":[{"given":"B","family":"Gojanovic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Liaudet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Gremion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36756","published-online":{"date-parts":[[2011,7,4]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1315\/1514","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1315\/1515","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1315\/1514","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T03:01:27Z","timestamp":1755226887000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,4]]},"references-count":0,"journal-issue":{"issue":"2728","published-online":{"date-parts":[[2011,7,4]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2011.13222","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,4]]}}}