{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:16:36Z","timestamp":1787062596966,"version":"build-2736575974"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"3940","license":[{"start":{"date-parts":[[2011,9,26]],"date-time":"2011-09-26T00:00:00Z","timestamp":1316995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>Oral devices, in particular Mandibular Advancement Splints (MAS), which hold the mandible in a  protruded position during sleep, are increasingly used for the treatment of  Obstructive Sleep Apnoea (OSA). These devices can be effective in treating OSA  across a range of severity. Complete resolution of OSA (Apnoea-Hypopnoea Index  [AHI] reduced &lt;5\/hr) with use of an MAS occurs in around 40% of patients.  Overall two thirds of patients experience some clinical benefit (\u226550% AHI  reduction AHI) however others will not objectively respond to this form of  treatment, despite improvement in symptoms. Although MAS are less  efficacious in reducing polysomnographic indices of OSA than the standard  treatment, Continuous Positive Airway Pressure (CPAP), improvements in health  outcomes appear to be comparable. Therefore, the superiority of CPAP in  improving oxygen desaturations and reducing AHI may be extenuated by its low  compliance, resulting in both treatments having similar effectiveness in  clinical practice. MAS are now recommended as a first line treatment  for mild to moderate OSA, as well as in more severe patients who are unable to  tolerate or refuse CPAP. Success with MAS treatment has been associated  with factors such as female gender, younger age, supine-dependent OSA, lower  BMI, smaller neck circumference and craniofacial factors, however a reliable,  validated method for prediction in the clinical setting has yet to be  established. MAS are well tolerated, however short-term side effects  are common although generally minor and transient. Long-term dental changes are  for the most part subclinical, but can be problematic for a minority of  patients. MAS are a dental-based treatment for a medical sleep  disorder and, as such, an interdisciplinary care model is considered important  for the attainment of optimal patient outcomes.<\/jats:p>","DOI":"10.4414\/smw.2011.13276","type":"journal-article","created":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T03:48:08Z","timestamp":1319687288000},"page":"w13276","source":"Crossref","is-referenced-by-count":21,"title":["Mandibular  advancement splints for the treatment of\u00a0sleep\u00a0apnoea syndrome"],"prefix":"10.57187","volume":"141","author":[{"given":"K","family":"Sutherland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Cistulli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36756","published-online":{"date-parts":[[2011,9,26]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1344\/1572","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1344\/1573","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1344\/1572","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T03:07:58Z","timestamp":1755227278000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,26]]},"references-count":0,"journal-issue":{"issue":"3940","published-online":{"date-parts":[[2011,9,26]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2011.13276","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,26]]}}}