{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T15:04:15Z","timestamp":1784300655908,"version":"3.55.0"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"1920","license":[{"start":{"date-parts":[[2012,5,6]],"date-time":"2012-05-06T00:00:00Z","timestamp":1336262400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>The recommendations  of international scientific societies for the treatment of hypertension in the  geriatric population are different. Lack of outcome trials, non-standardised  terminology as well as differing levels of evidence contribute to the inconsistencies  in the guidelines. This review article compares six international guidelines  (ESH-ESC 2007\/2009, SHG 2009, DHL\u00a02008, CHEP 2010, NICE 2011 and JNC7 2003) as  well as the consensus document of the ACCF\/AHA 2011 in terms of their  recommendations of drug classes, target blood pressure values and the use of combination  therapy. Generally, antihypertensive therapy appears to be clinically  beneficial in geriatric patients. Target blood pressure values of &lt;140\u2013150\/90\u00a0mm\u00a0Hg and &lt;140\/90\u00a0mm\u00a0Hg can be used as a general guideline for octogenarians  (80\u201389 yrs) and septuagenarians  (70\u201379 yrs) respectively. While angiotensin-II converting enzyme inhibitors and  diuretics appear to be advantageous in treating combined systolic-diastolic  hypertension, calcium-channel blockers and diuretics are to be recommended in  the management of isolated systolic hypertension. Combination therapy often  increases the efficacy of the treatment as well as patient medication adherence.  Furthermore, by making the most of drug combination synergy, lower doses may be  used resulting in fewer side-effects.<\/jats:p>","DOI":"10.4414\/smw.2012.13574","type":"journal-article","created":{"date-parts":[[2012,5,14]],"date-time":"2012-05-14T16:02:49Z","timestamp":1337011369000},"page":"w13574","source":"Crossref","is-referenced-by-count":6,"title":["Recommendations  for the treatment of hypertension in the elderly and very elderly \u2013 a\u00a0scotoma within  international guidelines"],"prefix":"10.57187","volume":"142","author":[{"given":"Hans Hendrik","family":"Sch\u00e4fer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob Daniel","family":"De Villiers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Sudano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Dischinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian-Reto","family":"Theus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Zilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dieterle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36756","published-online":{"date-parts":[[2012,5,6]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1482\/1848","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1482\/1849","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1482\/1848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T03:46:03Z","timestamp":1755229563000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,6]]},"references-count":0,"journal-issue":{"issue":"1920","published-online":{"date-parts":[[2012,5,7]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2012.13574","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,6]]}}}