{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:22:03Z","timestamp":1789730523625,"version":"4.0.1"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"3334","license":[{"start":{"date-parts":[[2012,8,12]],"date-time":"2012-08-12T00:00:00Z","timestamp":1344729600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>BACKGROUND:  Goitre recurrence is a common problem following subtotal thyroid gland  resection for multinodular goitre disease. The aim of the present study was to  evaluate morbidity rate in relation to the side of initial and redo-surgery for  recurrent disease.\n        METHODS: A  total of 1699 patients underwent consecutive thyroid gland surgery between 1997  and 2010 at our institution. One hundred and eighteen patients (6.9%) underwent  redo-surgery for recurrent disease after subtotal resection. One hundred and  nine patients with complete follow-up were included in the present study.\n        RESULTS:  Recurrent disease was found in 79 patients (72.5%) in the ipsilateral lobe and  in 30 patients (27.5%) in the contralateral lobe. The incidence of permanent  recurrent laryngeal nerve palsy was significantly higher in patients undergoing  redo-surgery on the ipsilateral lobe compared to patients undergoing initial  operation (3.8% vs. 1.1%; p = 0.03), whereas no difference was found in  patients with contralateral redo-surgery compared to patients undergoing  initial operation (p = 1.0). Independent risk factors for contralateral  recurrent disease were age at primary operation &lt;37 years (OR 4.86; 95% CI  1.58\u201315.01) and time to recurrence &lt;20 years (OR 6.53; 95% CI 2.23\u201319.01).\n        CONCLUSION:  Morbidity rate for recurrent disease after subtotal resection was significantly  higher for ipsilateral redo-surgery compared to initial surgery, whereas  redo-surgery can be performed safely on the contralateral lobe. Young age at  primary operation and short time to recurrence are independent risk factors for  contralateral recurrent disease.<\/jats:p>","DOI":"10.4414\/smw.2012.13643","type":"journal-article","created":{"date-parts":[[2012,9,3]],"date-time":"2012-09-03T14:22:36Z","timestamp":1346682156000},"page":"w13643","source":"Crossref","is-referenced-by-count":9,"title":["Morbidity  rate of reoperation in thyroid surgery: a\u00a0different\u00a0point of view"],"prefix":"10.57187","volume":"142","author":[{"given":"Anita","family":"Kurmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uta","family":"Herden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan\u00a0W.","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Candinas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian\u00a0A.","family":"Seiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36756","published-online":{"date-parts":[[2012,8,12]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1556\/1996","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1556\/1997","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1556\/1996","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T04:01:43Z","timestamp":1755230503000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1556"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,12]]},"references-count":0,"journal-issue":{"issue":"3334","published-online":{"date-parts":[[2012,8,13]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2012.13643","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,12]]}}}