{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:25:13Z","timestamp":1792290313923,"version":"4.4.0"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"4748","license":[{"start":{"date-parts":[[2012,11,18]],"date-time":"2012-11-18T00:00:00Z","timestamp":1353196800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>Branded in  2005, \u201cneglected tropical diseases\u201d have gained traction in terms of advocacy,  interest for research, enhanced funding and political will for their control  and eventual elimination. Starting with an initial set of 13 neglected tropical  diseases \u2013 seven helminth, three bacterial and three protozoal infections \u2013 the  list considerably expanded to more than 40 diseases that now also includes viral,  fungal and ectoparasitic infections. In this review, we provide a comprehensive  overview of the neglected tropical diseases, their causative agents and the  current geographical distribution, including their importance for the general practitioners  seeing returning travellers and migrants in Switzerland. We characterise the  most important of the neglected tropical diseases in terms of at-risk  population, estimated number of infections, annual mortality rates and global  burden, including current knowledge gaps. With an emphasis on neglected  tropical diseases due to helminths, protozoa and ectoparasites, we review  common diagnostic methods and current recommendations for treatment at the population  level and the individual patient, thereby juxtaposing the situation in highly  endemic countries on one side, with Switzerland on the other. We highlight the  clinical presentation and management of the neglected tropical diseases in  general and then elaborate on two examples, strongyloidiasis and leptospirosis.  Our review provides a global perspective of neglected tropical diseases and we  hope that it will prove useful for the general practitioner and clinician in  Switzerland and elsewhere to enhance their suspicion index, differential  diagnosis, clinical management and treatment, including referral to specialised  clinics and laboratories when need be.<\/jats:p>","DOI":"10.4414\/smw.2012.13727","type":"journal-article","created":{"date-parts":[[2012,12,20]],"date-time":"2012-12-20T06:43:50Z","timestamp":1355985830000},"page":"w13727","source":"Crossref","is-referenced-by-count":97,"title":["Neglected  tropical diseases: diagnosis, clinical management, treatment and control"],"prefix":"10.57187","volume":"142","author":[{"given":"J\u00fcrg","family":"Utzinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f6ren L.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Knopp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Blum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas L.","family":"Neumayr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Keiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph F.","family":"Hatz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36756","published-online":{"date-parts":[[2012,11,18]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1615\/2112","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1615\/2113","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1615\/2112","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T04:14:24Z","timestamp":1755231264000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,18]]},"references-count":0,"journal-issue":{"issue":"4748","published-online":{"date-parts":[[2012,11,19]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2012.13727","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,18]]}}}