{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:34:15Z","timestamp":1789389255484,"version":"build-2803163510"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"0708","license":[{"start":{"date-parts":[[2013,2,10]],"date-time":"2013-02-10T00:00:00Z","timestamp":1360454400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>QUESTION UNDER  STUDY: Data on pain management in haemodialysis patients with end-stage renal  disease are scanty. Our study aimed to collect information on the frequency and  severity of pain and symptom distress among long-term dialysis patients in southern  Switzerland.\n        METHODS: Patients  with chronic kidney disease stage 5, on dialysis, treated in five nephrology  units in southern Switzerland, who had given informed consent and were able to  complete the survey, were interviewed to assess pain and correlated symptoms  using a Visual Analogue Scale (VAS), the Brief Pain Inventory and the Edmonton Symptom Assessment System. To  evaluate the impact of symptoms, the Instrumental Activities of Daily Living  questionnaire was used.\n        RESULTS: One  hundred and twenty-three patients, aged 36\u201390 years and with a mean time on dialysis of 3.5  years, were interviewed. Pain was experienced by 81 patients during  the 4 weeks before the interview: 68 had chronic pain; 66 reported pain  intensity higher than 5 on the VAS; 35 identified musculoskeletal pain as the  most disturbing pain. Five patients used drugs to cope with pain during the night. Asthenia and fatigue were prevalent  concomitant symptoms. Asthenia, fatigue, sleep disturbances, dyspnoea, loss of  appetite, nausea\/vomiting and anxiety were correlated with pain. The majority  of the patients reported that their pain limited their daily life activities.\n        CONCLUSIONS: Pain severity and symptom distress in dialysis patients are important,  but underestimated and undertreated. They interfere with sleep quality and  daily living. Routine assessment of pain burden, pain management similar to  that used in palliative care, and adequate analgesic use to treat specific  dialysis-associated pain syndromes should be considered in guidelines.<\/jats:p>","DOI":"10.4414\/smw.2013.13750","type":"journal-article","created":{"date-parts":[[2013,4,17]],"date-time":"2013-04-17T06:29:02Z","timestamp":1366180142000},"page":"w13750","source":"Crossref","is-referenced-by-count":30,"title":["Frequency and severity of  pain and symptom distress among patients with chronic kidney disease receiving  dialysis"],"prefix":"10.57187","volume":"143","author":[{"given":"Claudia","family":"Gamondi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Galli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Sch\u00f6nholzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Marone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Zwahlen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Gabutti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Ferrier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Cereghetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Giannini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36756","published-online":{"date-parts":[[2013,2,10]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1648\/2176","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1648\/2177","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1648\/2176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T04:20:07Z","timestamp":1755231607000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,10]]},"references-count":0,"journal-issue":{"issue":"0708","published-online":{"date-parts":[[2013,2,11]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2013.13750","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,10]]}}}