{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:50:09Z","timestamp":1791085809268,"version":"4.1.0"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"3132","license":[{"start":{"date-parts":[[2013,7,28]],"date-time":"2013-07-28T00:00:00Z","timestamp":1374969600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>QUESTION UNDER  STUDY: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative  disease with a poor prognosis. Survival and quality of life of ALS patients  have improved through the implementation of multidisciplinary approaches, the  use of percutaneous gastrostomy and of noninvasive (NIV) or invasive  ventilation. The\u00a0question of whether or not to propose invasive ventilation (by  tracheostomy: TPPV) to ALS patients remains a matter of debate.\n        METHODS: The  study reviews the medical literature, the practice in three Swiss and two large  French ALS expert centres and reports the results of a workgroup on invasive  ventilation in ALS.\n        RESULTS: Improved  management of secretions and use of  different interfaces allows NIV to be used 24-hours-a-day  for prolonged periods, thus avoiding TPPV in many cases. TPPV is frequently  initiated in emergency situations with lack of prior informed consent. TPPV  appears associated with a lesser quality of life and a higher risk of  institutionalisation than NIV. The high burden placed on caregivers who manage  ALS patients is a major problem with a clear impact on their quality of life.\n        CONCLUSIONS:  Current practice in Switzerland and France tends to discourage the use of TPPV  in ALS. Fear of a \u201clocked-in syndrome\u201d, the high burden placed on caregivers, and  unmasking cognitive disorders occurring in the evolution of ALS are some of the  caveats when considering TPPV. Most decisions about TPPV are taken in emergency  situations in the absence of advance directives. One exception is that of young  motivated patients with predominantly bulbar disease who \u201cfail\u201d NIV.<\/jats:p>","DOI":"10.4414\/smw.2013.13830","type":"journal-article","created":{"date-parts":[[2014,7,3]],"date-time":"2014-07-03T10:27:23Z","timestamp":1404383243000},"page":"w13830","source":"Crossref","is-referenced-by-count":31,"title":["Is tracheostomy still an option in amyotrophic lateral\u00a0sclerosis?"],"prefix":"10.57187","volume":"143","author":[{"given":"Anne-Chantal","family":"Heritier-Barras","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Adler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruxandra","family":"Iancu Ferfoglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bara","family":"Ricou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvan","family":"Gasche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Leuchter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samia","family":"Hurst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Escher-Imhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Pollak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Paul","family":"Janssens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36756","published-online":{"date-parts":[[2013,7,28]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1719\/2320","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1719\/2321","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1719\/2320","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T04:38:48Z","timestamp":1755232728000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,28]]},"references-count":0,"journal-issue":{"issue":"3132","published-online":{"date-parts":[[2013,7,29]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2013.13830","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,28]]}}}