{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:05:21Z","timestamp":1774119921935,"version":"3.50.1"},"reference-count":0,"publisher":"SMW Supporting Association","issue":"3536","license":[{"start":{"date-parts":[[2013,8,25]],"date-time":"2013-08-25T00:00:00Z","timestamp":1377388800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>BACKGROUND:  Preventive treatment may avoid future cases of tuberculosis among asylum  seekers. The effectiveness of preventive treatment depends in large part on  treatment completion.\n        METHODS:  In a prospective cohort study, asylum seekers of two of the Swiss Canton Vaud migration  centres were screened with the Interferon Gamma  Release Assay (IGRA). Those with a positive IGRA were referred for medical  examination. Individuals with active or past tuberculosis were excluded.  Preventive treatment was offered to all  participants with positive IGRA but without active tuberculosis. The adherence  was assessed during monthly follow-up.\n        RESULTS:  From a population of 393 adult migrants, 98 (24.9%) had a positive IGRA. Eleven  did not attend the initial medical assessment. Of the 87 examined, eight presented with pulmonary disease (five of them received a full course of  antituberculous therapy), two had a history of prior tuberculosis treatment and  two had contraindications to treatment. Preventive treatment was offered to 75  individuals (4 months rifampicin in 74 and 9 months isoniazid in one), of whom  60 (80%) completed the treatment.\n        CONCLUSIONS:  The vulnerability and the volatility of this population make screening and  observance of treatment difficult. It seems possible to obtain a high rate of  completion using a short course of treatment in a closely monitored population  living in stable housing conditions.<\/jats:p>","DOI":"10.4414\/smw.2013.13860","type":"journal-article","created":{"date-parts":[[2014,7,3]],"date-time":"2014-07-03T10:27:23Z","timestamp":1404383243000},"page":"w13860","source":"Crossref","is-referenced-by-count":4,"title":["High  rate of completion of preventive therapy for\u00a0latent tuberculosis infection  among asylum seekers in a Swiss Canton"],"prefix":"10.57187","volume":"143","author":[{"given":"Apostolos","family":"Sarivalasis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Bodenmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Langenskiold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Lutchmaya- Flick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Daher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Pierre","family":"Zellweger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"36756","published-online":{"date-parts":[[2013,8,25]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1739\/2360","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1739\/2361","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/1739\/2360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T04:53:03Z","timestamp":1755233583000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/1739"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,25]]},"references-count":0,"journal-issue":{"issue":"3536","published-online":{"date-parts":[[2013,8,26]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2013.13860","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,25]]}}}