{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T21:53:36Z","timestamp":1722030816062},"reference-count":0,"publisher":"SMW Supporting Association","issue":"0910","license":[{"start":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T00:00:00Z","timestamp":1615420800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Med Wkly"],"abstract":"<jats:p>AIMS\n          Vitamin D deficiency remains very common in the general population. Adding to the importance of this issue is the discovery that vitamin D plays a role in many other tissues apart from the bone, including muscle, brain, prostate, breast and colon. In this study, we investigated the prevalence of vitamin D deficiency in a large group of patients hospitalised in the cantonal hospital Basel-Country, and analysed the dependence of serum vitamin D concentrations on gender, time of the year and age.\n        \n        \n          METHODS\n          We retrospectively analysed anonymised data received from the central laboratory of the cantonal hospital Basel-Country. The pool of data contains values obtained between 2013 and 2017 from 8861 patients aged between 18 and 102 years. If sequential measurements were available from a patient, only the first was used for the analyses. Vitamin D deficiency was defined as a serum concentration of &lt;50 nmol\/l and severe deficiency as &lt;25 nmol\/l. Vitamin D values between 50 and 75 nmol\/l are considered a grey zone. Optimal values are &gt;75 nmol\/l.\n        \n        \n          RESULTS\n          Mean \u00b1 standard deviation serum vitamin D concentration was 52.5 \u00b1 30.5 nmol\/l, with women having a higher mean of 55.5 \u00b1 31.5 nmol\/l as compared with 48.1 \u00b1 28.6 nmol\/l in men (p &lt;10-5). Of the 8861 first measurements taken within the observation period, 4527 (51%) were vitamin D deficient with levels &lt;50 nmol\/l, including 1860 (21.0%) with levels &lt;25 nmol\/l. There was only a weak positive association of average vitamin D levels with age (p = 0.06). Women reached peak concentrations of 56.9 \u00b1 35.4 nmol\/l in the age group 90\u2013102 years, whereas men reached peaks of 50.3 \u00b1 31.9 nmol\/l in 50\u201359-year-olds. Mean autumn and spring concentrations differed less (51.6 \u00b1 29.6 vs 52.7 \u00b1 30.7 nmol\/l, respectively, p = 0.38) than mean summer and winter concentrations (57.1 \u00b1 29.5 vs 48.0 \u00b1 31.2 nmol\/l, respectively, p &lt;10-5).\n        \n        \n          CONCLUSIONS\n          Vitamin D deficiency was a common finding in our cohort, affecting all age groups and occurring in over half (51%) of the values measured. As current guidelines recommend vitamin D concentrations &gt;75 nmol\/l, only 22.1% of measured values indicated adequate vitamin D levels. This issue should be addressed in order to improve quality of life and reduce medical costs.<\/jats:p>","DOI":"10.4414\/smw.2021.20470","type":"journal-article","created":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T22:46:40Z","timestamp":1615675600000},"page":"w20470","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence of vitamin D deficiency in an inpatient population in the Swiss Canton of Basel-Country"],"prefix":"10.57187","volume":"151","author":[{"given":"Jonathan","family":"Benhamou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Schindler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Rutishauser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"36756","published-online":{"date-parts":[[2021,3,11]]},"container-title":["Swiss Medical Weekly"],"original-title":[],"link":[{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/2971\/4904","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/2971\/4905","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/download\/2971\/4905","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T22:38:45Z","timestamp":1674772725000},"score":1,"resource":{"primary":{"URL":"https:\/\/smw.ch\/index.php\/smw\/article\/view\/2971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,11]]},"references-count":0,"journal-issue":{"issue":"0910","published-online":{"date-parts":[[2021,3,1]]}},"URL":"https:\/\/doi.org\/10.4414\/smw.2021.20470","relation":{},"ISSN":["1424-3997"],"issn-type":[{"value":"1424-3997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,11]]}}}