{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:50:15Z","timestamp":1775148615691,"version":"3.50.1"},"reference-count":70,"publisher":"American Spinal Injury Association","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020]]},"abstract":"\n Background:<\/jats:title>\n Acute flaccid myelitis (AFM) is an illness defined by rapid onset of flaccid paralysis in one or more limbs or bulbar muscles, with MRI findings of predominantly spinal cord gray matter abnormalities spanning one or more spinal segments following a viral illness. Individuals with AFM may require rehabilitation to promote recovery. Activity-based restorative therapy (ABRT) has previously been shown to result in positive outcomes in children with neurologic deficits related to AFM.<\/jats:p>\n <\/jats:sec>\n \n Objectives:<\/jats:title>\n This study examined functional changes in a group of children with AFM who participated in ABRT in an inpatient setting.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Retrospective chart review of children with AFM admitted to a single inpatient rehabilitation unit from 2014 to 2018. Children were assessed using the Functional Independence Measure for Children (WeeFIM), Manual Muscle Testing (MMT), Spinal Cord Independence Measure (SCIM), and the Physical Abilities and Mobility Scale (PAMS) as part of routine clinical care; the Modified Rankin Scale for Neurologic Disability was completed retrospectively.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Children showed significant improvements across all outcome measures, with effect sizes ranging from moderate to large. Significant change was also seen across all muscle groups on MMT, with effect sizes ranging from small to large. Consistent with previous reports, children demonstrated better function in distal than proximal muscle groups at both admission and discharge.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Children with AFM who participated in ABRT increased muscle strength and made functional gains across all outcome measures. These results support the utility of rehabilitation in the long-term care of children with AFM and residual neurologic deficit.<\/jats:p>\n <\/jats:sec>","DOI":"10.46292\/sci20-00010","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T14:25:17Z","timestamp":1611930317000},"page":"275-282","source":"Crossref","is-referenced-by-count":7,"title":["Improvements in Function Following Inpatient Activity-Based Therapy for Children With Acute Flaccid Myelitis"],"prefix":"10.46292","volume":"26","author":[{"given":"Kaitlin","family":"Hagen","sequence":"first","affiliation":[{"name":"International Center for Spinal Cord Injury, Kennedy Krieger Institute, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney","family":"Porter","sequence":"additional","affiliation":[{"name":"International Center for Spinal Cord Injury, Kennedy Krieger Institute, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Martin","sequence":"additional","affiliation":[{"name":"International Center for Spinal Cord Injury, Kennedy Krieger Institute, Baltimore, Maryland"},{"name":"Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Dean","sequence":"additional","affiliation":[{"name":"International Center for Spinal Cord Injury, Kennedy Krieger Institute, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Salorio","sequence":"additional","affiliation":[{"name":"International Center for Spinal Cord Injury, Kennedy Krieger Institute, Baltimore, Maryland"},{"name":"Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Sadowsky","sequence":"additional","affiliation":[{"name":"International Center for Spinal Cord Injury, Kennedy Krieger Institute, Baltimore, Maryland"},{"name":"Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"25425","reference":[{"issue":"12","key":"i1082-0744-26-4-275-b1","series-title":"Curr Treat Options Neurol","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1007\/s11940-017-0480-3","article-title":"Acute flaccid myelitis: Etiologic challenges, diagnostic and management considerations","volume":"19","year":"2017","unstructured":"Hopkins\n SE.\n \n \n Acute flaccid myelitis: Etiologic challenges, diagnostic and management considerations.\n\t\t\t\t\tCurr Treat Options 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Neurol.\n\t\t\t\t\t1996;\n\t\t\t\t\t38(\n\t\t\t\t\t10):\n\t\t\t\t\t907\u2013\n\t\t\t\t\t916.\n\t\t\t\t\tdoi:10.1111\/j.1469-8749.1996.tb15047.x"},{"issue":"7","key":"i1082-0744-26-4-275-b22","series-title":"Clin Pediatr (Phila)","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1177\/000992289403300708","article-title":"The Functional Independence Measure for Children (WeeFIM): Conceptual basis and pilot use in children with developmental disabilities","volume":"33","year":"1994","unstructured":"Msall\n ME,\n \n \n DiGaudio\n K,\n \n \n Rogers\n BT,\n \n \n .\n\t\t\t\t\tThe Functional Independence Measure for Children (WeeFIM): Conceptual basis and pilot use in children with developmental disabilities.\n\t\t\t\t\tClin Pediatr (Phila).\n\t\t\t\t\t1994;\n\t\t\t\t\t33(\n\t\t\t\t\t7):\n\t\t\t\t\t421\u2013\n\t\t\t\t\t430.\n\t\t\t\t\tdoi:10.1177\/000992289403300708"},{"issue":"5","key":"i1082-0744-26-4-275-b23","series-title":"J Head Trauma 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